Partial demasculinization of several brain regions in adult male (XY) rats with a dysfunctional androgen receptor gene

The adult rat posterodorsal medial amygdala (MePD) is sexually dimorphic in regional volume and neuronal soma size, both of which are larger in males than in females. This sexual dimorphism is entirely dependent on adult circulating levels of testicular androgens, and both androgen and estrogen t…