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Binding of DNA Nucleobases and Nucleosides with Graphene

Varghese, Neenu, Mogera, Umesha, Govindaraj, Achutharao, Das, Anindya, Maiti, Prabal K., Sood, Ajay K., Rao, C. N. R.·2009·ChemPhysChem

Abstract

Interaction of two different samples of graphene with DNA nucleobases and nucleosides is investigated by isothermal titration calorimetry. The relative interaction energies of the nucleobases decrease in the order guanine (G)>adenine (A)>cytosine (C)>thymine (T) in aqueous solutions, although the positions of C and T seem to be interchangeable. The same trend is found with the nucleosides. Interaction energies of the A–T and G–C pairs are somewhere between those of the constituent bases. Theoretical calculations including van der Waals interaction and solvation energies give the trend G>A∼T>C. The magnitudes of the interaction energies of the nucleobases with graphene are similar to those found with single‐walled carbon nanotubes.

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Metadata

Authors
Varghese, N., Mogera, U., Govindaraj, A., Das, A., Maiti, P. K., Sood, A. K., & Rao, C. N. R.
Venue
ChemPhysChem
Publisher
Wiley
Published
2009-01-07
Volume
10
Issue
1
Pages
206-210
ISSN
  • 1439-4235 (ISSN-L)
  • 1439-7641
OpenAlex
W2052480089
Cited by
531
References
0
FWCI
15.66
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Binding of DNA Nucleobases and Nucleosides with Graphene. https://app.cochat.ai/papers/10.1002/cphc.200800459
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Varghese, N., Mogera, U., Govindaraj, A., Das, A., Maiti, P. K., Sood, A. K., & Rao, C. N. R. (2009). Binding of DNA Nucleobases and Nucleosides with Graphene. ChemPhysChem. https://doi.org/10.1002/cphc.200800459

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