Face-to-face versus remote administration of the Montgomery-Asberg Depression Rating Scale using videoconference and telephone
Abstract
Although the use of telemedicine in psychiatry has a long history in providing clinical care to patients, its use in clinical trials research has not yet been commonly employed. Telemedicine allows for the remote assessment of study patients, which could be done by a centralized, highly calibrated, and impartial cohort of raters independent of the study site. This study examined the comparability of remote administration of the Montgomery-Asberg Depression Rating Scale (MADRS) by videoconference and by telephone to traditional face-to-face administration. Two parallel studies were conducted: one compared face-to-face with videoconference administration (N=35), and the other compared face-to-face with telephone administration (N=35). In each study, depressed patients were interviewed independently twice: once in the traditional face-to-face manner, and the second time by either videoconference or teleconference. A counterbalanced order was used. The mean MADRS score for interviews conducted remotely by videoconference was not significantly different from the mean MADRS scores conducted by face-to-face administration (mean difference=0.51 points), P=.388, intraclass correlation (ICC)=.94, P<0001. Similarly, the mean MADRS score for interviews conducted by telephone was not significantly different from the mean MADRS score conducted by face-to-face administration (mean difference=0.74 points), P=.270, ICC=.93, P<0001. Results of the study support the comparability of remote admi…
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A minimal clinically important difference (MCID) in change in MADRS score was not prespecified, although depression trial literature supports a placebo-adjusted change in score as low as 2 and as high as 9 and an absolute change from pretreatment of 6 as clinically meaningful and a change of 12 as clinically substantial.
“A minimal clinically important difference (MCID) in change in MADRS score was not prespecified, although depression trial literature supports a placebo-adjusted change in score as low as 2 and as high as 9 and an absolute change from pretreatment of 6 as clinically meaningful and a change of 12 as clinically substantial.25,26”
From Single-Dose Psilocybin Treatment for Major Depressive Disorder: A Randomized Clinical Trial (2023) · cites this paper as [26]
The use of telephone measures is a method now being used in clinical trials to reduce bias.
“The use of telephone measures is a method now being used in clinical trials to reduce bias (Kobak et al., 2008).”
The validity of using standardized central rating via telephone correlates well with face-to-face interviews.
“it is important to note that the validity of using standardized central rating via telephone correlates well with face-to-face interviews (Kobak et al., 2008)”
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References 35 · Cited by 50
- Authors
- Kobak, K. A., Williams, J. B. W., Jeglic, E., Salvucci, D., & Sharp, I. R.
- Affiliations
- Columbia University (US)
- John Jay College of Criminal Justice (US)
- Corresponding author
- Kobak, Kenneth A.
- Venue
- Depression and Anxiety
- Publisher
- Hindawi Limited
- Published
- 2008-11
- Volume
- 25
- Issue
- 11
- Pages
- 913-919
- ISSN
- 1091-4269 (ISSN-L)
- 1520-6394
- OpenAlex
- W2060856863
- Cited by
- 50
- References
- 35
- Citations by year
- 2025: 3 · 2024: 3 · 2023: 8 · 2022: 2 · 2021: 4 · 2020: 3 · 2019: 4 · 2018: 2 · 2017: 3 · 2016: 2 · 2015: 4 · 2014: 2 · 2013: 2 · 2012: 2
- FWCI
- 2.06
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Depression and Anxiety (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Keywords
- Montgomery-Asberg Depression Rating Scale, remote administration, videoconferencing, telephone administration, telemedicine, depression assessment, inter-rater reliability, clinical trials, remote patient assessment
- MeSH terms
- Adult, Aged, Major Depressive Disorder, Female, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Telephone, Visual Perception, Patient Satisfaction, Diagnostic and Statistical Manual of Mental Disorders, Videoconferencing, Young Adult
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