KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID‐ACTING ANTIDEPRESSANTS

Abdallah, Chadi G., Adams, Thomas G., Kelmendi, Benjamin, Esterlis, Irina, Sanacora, Gerard, Krystal, John H.·2016·Depression and Anxiety

Cited by (207)

Items 101–200 of 207

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  3. Trends in Pediatric Pain
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  4. Prophylactic efficacy of ketamine, but not the low-trapping NMDA receptor antagonist AZD6765, against stress-induced maladaptive behavior and 4E-BP1-related synaptic protein synthesis impairment
    Anderson Camargo, Ana Clara N. C. Torrá, Ana Paula Dalmagro, Ana Paula Valverde, Bruna R. Kouba, Daiane B. Fraga, Eloise C. Alves, Ana Lúcia S. Rodrigues · 2022 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  5. Molecular Signaling Mechanisms for the Antidepressant Effects of NLX-101, a Selective Cortical 5-HT1A Receptor Biased Agonist
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  6. Acute administration of the NMDA receptor antagonists ketamine and MK-801 reveals dysregulation of glutamatergic signalling and sensorimotor gating in the Sapap3 knockout mouse model of compulsive-like behaviour
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  7. Ketamine induces opposite changes in AMPA receptor calcium permeability in the ventral tegmental area and nucleus accumbens
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  8. Acute effects of ketamine on the pregenual anterior cingulate: linking spontaneous activation, functional connectivity, and glutamate metabolism
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  9. Psilocybin-assisted psychotherapy for dying cancer patients – aiding the final trip
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  10. Patient-reported outcomes on sleep quality and circadian rhythm during treatment with intravenous ketamine for treatment-resistant depression
    R. Yan, Tyler Marshall, A. Khullar, T. Nagle, J. Knowles, M. Malkin, Brittany Chubbs, J. Swainson · 2024 · Therapeutic Advances in Psychopharmacology
  11. Efficacy of Esketamine among patients with treatment resistant depression in a ‘real world' health-care setting in Israel
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  12. Ketamine reverses chronic corticosterone-induced behavioral deficits and hippocampal synaptic dysfunction by regulating eIF4E/BDNF signaling
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  13. REL-1017 (Esmethadone), A Novel NMDAR Blocker for the Treatment of MDD is Not Neurotoxic in Sprague-Dawley Rats
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  14. Neuroimaging as a Tool for Individualized Treatment Choice in Depression: the Past, the Present and the Future
    Beata R. Godlewska · 2020 · Current Behavioral Neuroscience Reports
  15. S-ketamine ameliorates post-stroke depression in mice via attenuation of neuroinflammation, synaptic restoration, and BDNF pathway activation
    Tian, Jiaxin, Xie, Yanhong, Ye, Sen, Hu, Yongfeng, Feng, Jiaxin, Li, Yi, Lou, Zhongze, Ruan, Liemin, Wang, Zhengchun · 2025 · Biochemical and Biophysical Research Communications
  16. Repeated cannabidiol treatment affects neuroplasticity and endocannabinoid signaling in the prefrontal cortex of the Flinders Sensitive Line (FSL) rat model of depression.
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  17. Spike firing attenuation of serotonin neurons in learned helplessness rats is reversed by ketamine
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  18. Combined Treatment with Low-Dose Ionizing Radiation and Ketamine Induces Adverse Changes in CA1 Neuronal Structure in Male Murine Hippocampi
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  19. Kétamine, psilocybine, et antidépresseurs d'action rapide : de nouvelles promesses pour la psychiatrie?
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  21. NMDA Antagonists and Their Role in the Management of Bipolar Disorder: a Review
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  22. Guanosine as a promising target for fast-acting antidepressant responses
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  23. The metabotropic glutamate receptor 5 as a biomarker for psychiatric disorders
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  24. Effects of stress on endophenotypes of suicide across species: A role for ketamine in risk mitigation
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  25. A single subanaesthetic dose of the rapid-acting antidepressant S-ketamine raises presynaptic SV2A density in limbic regions of the Wistar Kyoto rat model of depression
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  26. Guanosine boosts the fast, but not sustained, antidepressant-like and pro-synaptogenic effects of ketamine by stimulating mTORC1-driven signaling pathway
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  27. Increase in PAS-induced neuroplasticity after a treatment course of intranasal ketamine for depression. Report of three cases from a placebo-controlled trial
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  28. Functional activity and connectivity signatures of ketamine and lamotrigine during negative emotional processing: a double-blind randomized controlled fMRI study
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  29. Automated Depression Detection from Tweets: a Comparison of NLP Techniques
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  30. Lost in descent: Complications of cryptorchidism
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  31. The pharmacokinetics of ketamine following intramuscular injection to F344 rats
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  32. Preclinical toxicological study of prolonged exposure to ketamine as an antidepressant
    Julia Zaccarelli‐Magalhães, André Rinaldi Fukushima, Natália Chermont dos Santos Moreira, Marianna Manes, Gabriel Abreu, Esther Lopes Ricci, Paula A. Faria Waziry, Helenice de Souza Spinosa · 2019 · Pharmacological Reports
  33. The immunomodulatory effect of ketamine in depression.
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  34. Simultaneous Application of Lidocaine and Ketamine During Ambulatory Infusion Therapy: A Retrospective Analysis
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  35. Effect of Acute Ketamine Treatment on Sympathetic Regulation Indexed by Electrodermal Activity in Adolescent Major Depression
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  36. PACAP/VIP in the prefrontal cortex mediates the rapid antidepressant effects of zhizichi decoction
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  37. Putative effects of cannabidiol in depression and synaptic plasticity
    Sâmia R.L. Joca, Gabriela Pandini Silote, Ariandra Guerini Sartim, Amanda J. Sales, Francisco Silveira Guimarães, Gregers Wegener · 2021 · Elsevier eBooks
  38. Clinical use of ketamine in psychiatric disorders
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  39. Phosphoproteomics implicates glutamatergic and dopaminergic signalling in the antidepressant-like properties of the iron chelator deferiprone
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  40. Gender Differences in Adverse Events of Ketamine Drugs: A Real‐World Study Based on FAERS
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  42. Modulation of functional network co-activation pattern dynamics following ketamine treatment in major depression
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  43. Ketamine enhances neurological function through neuronal and plasticity-related protein changes in rats with permanent middle cerebral artery occlusion
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  44. An effect of 3-oxypyridine and succinic acid derivatives on the time of reduction of anxiety and depression symptoms in alcohol withdrawal treatment
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  45. Ketamine causes poor maternal care in rats with postpartum depression and leads to few behavioral and neurochemical alterations on male offspring
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  47. Structure-Based Virtual Screening to Identify Negative Allosteric Modulators of NMDA
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  48. A qualitative investigation of the Montgomery–Åsberg depression rating scale: discrepancies in rater perceptions and data trends in remote assessments of rapid-acting antidepressants in treatment resistant depression
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  49. Recent advances in the synthesis of antidepressant derivatives: pharmacologic insights for mood disorders
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  54. Ketamine combined with psychotherapy for treatment-resistant depression: Real-world outcomes and the role of subjective experience
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