Blockade of PD‐1 or p38 MAP kinase signaling enhances senescent human CD8+ T‐cell proliferation by distinct pathways
Henson, Sian M., Macaulay, Richard, Riddell, Natalie E., Nunn, Craig J., Akbar, Arne N.·2015·European Journal of Immunology
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- Immunosenescence and Cancer Immunotherapy at Old Age: BasicsTamàs Fülöp, Jacek Maciej Witkowski, K. Hirokawa, Anis Larbi, Graham Pawelec · 2020 · Springer eBooks
- Charlson syndrome index predicted survival in pancreatic cancer patients received immunotherapyNan Zhang, Shiyun Chen, Yue Shi, Zhikuan Wang, Ru Jia, Guanghai Dai · 2025 · Frontiers in Immunology
- Multiplex engineering and multifunction T cells for precise and effective immunotherapiesLeila Jafarzadeh, Ali Smaani, Jean‐Sébastien Delisle · 2025 · Frontiers in Immunology
- From Inflamm-Aging to ImmunosenescenceTamàs Fülöp, Jacek Maciej Witkowski, Alan Arthur Cohen, Gilles Dupuis, Katsuiku Hirokawa, Anis Larbi · 2019 · Cambridge University Press eBooks
- T-Cell Immunosenescence in Systemic Lupus Erythematosus: Molecular Mechanisms and Therapeutic PerspectivesSuqing Zhou, Lian Jian, Hui Chen, Huan Yin, Fanghan Ji, Ming Yang, Haijing Wu · 2026 · Clinical Reviews in Allergy & Immunology
- T cell senescence and exhaustion: molecular mechanisms and immune rejuvenation for cancer immunotherapyLauren van den Broecke, Arne Van der Vreken, Fenja Watté, Fien Meeus, Kim De Veirman, Karine Breckpot, Elke De Bruyne, Eline Menu · 2026 · Signal Transduction and Targeted Therapy
- Senescent T Cells: The Silent Culprit in Acute Myeloid Leukemia Progression?Xiaolan Zhang, Lingbo Liu · 2024 · International Journal of Molecular Sciences
- When wrinkles appear on the immune system can it be reversed?Hiba Sibaii, Salwa Refat El-Zayat, M. Khalil · 2020 · European Cytokine Network
- Physical activity modifies the metabolic profile of CD4+ and CD8+ T cell subtypes at rest and upon activation in older adultsEdward Withnall, Jon Hazeldine, Alba Llibre, Niharika Arora Duggal, Janet M. Lord, Amanda Veiga Sardeli · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Immune checkpoint inhibition in the context of agingConstantin N. Baxevanis, Ourania Tsitsilonis · 2025 · Ageing and Cancer Research & Treatment
- Advanced immunology in aging population: unveiling the complexities of vaccine responsivenessYan Han, Yanhao Huang, Yuanyu Zhou, Wanke He, Gaomei Luo, Liu Yang, Yanbin Chen, Yiqi Zhu, Wei Jiang, Chanchan Xiao et al. · 2025 · Frontiers in Aging
- Bridging aging and colorectal cancer: synergistic roles of inflammaging and immunosenescenceSilvère D. Zaongo, Qiyu Yang, Mei Han, Tianlan Xi, Zilang Luo, Xin Wang, Jiadan Yang, Jing Ouyang · 2026 · Frontiers in Immunology
- Signal Transduction Changes in T Cells with AgingTamàs Fülöp, Aurélie Y. Le Page, Gilles Dupuis, Carl F Fortin, Jacek Maciej Witkowski, Anis Larbi · 2019 · Springer eBooks
- A silver bullet for ageing medicine?: clinical relevance of T-cell checkpoint receptors in normal human ageingLeanne Rimmer, Derek A. Mann, Avan Aihie Sayer, Shoba Amarnath, Antoneta Granic · 2024 · Frontiers in Immunology
- Immunotherapy: should we worry about immunosenescence?A. Özkan, Nienke Aafke de Glas, Johanneke E. A. Portielje · 2024 · Ageing and Cancer Research & Treatment
- T Cell Aging: An Important Target for Perioperative ImmunomodulationHaoning Lan, Shuyun Xu, Huili Li, Ruijuan Guo, Zhong Feng, Yun Wang · 2025 · Clinical Interventions in Aging
- Vitiligo as a potential degenerative disease: from oxidative stress to cellular senescenceYaojun Wang, Jiaoni Chi, Tao Wang, Yue Zhang, Zhimin Li, Jie Chen, Haixia Liu, Qiang Li · 2022 · Aging Pathobiology and Therapeutics
- Human Cytomegalovirus as a driving force towards ImmunosenescenceZdeněk Zadražil · 2018
- Effects of Ageing on Adaptive Immune ResponsesSiân M. Henson · 2016 · Springer eBooks
- Immunological Methods and the Concept of Inflammaging in the Study of Human AgingTamàs Fülöp, Graham Pawelec, Jacek Maciej Witkowski, Alan Arthur Cohen, Carl F Fortin, Aurélie Y. Le Page, Hugo Garneau, Gilles Dupuis, Anis Larbi · 2018 · Elsevier eBooks
- Immune checkpoint pathways in the ageing immune system and their relation to vasculitidesRebeca Hid Cadena · 2020
- AGING WITH T CELLSPieren, Daniël Kees Johan · 2021
- Estudio celular de la inmunosenescencia en adultos mayores vacunados y en pacientes con cáncer de mamaRodríguez Rodríguez, Ivon Johanna · 2021
- Signal Transduction Changes in T-Cells with AgingTamàs Fülöp, Aurélie Y. Le Page, Gilles Dupuis, Carl F Fortin, Jacek Maciej Witkowski, Anis Larbi · 2018 · Springer eBooks
- Clinical outcomes and safety of PD-1 inhibitors therapy in elderly patients with advanced gastric cancerJuanjuan Zhou, Yunlong Cai, Zhen Chen, Xiaomei Zhang, Xiaojun Xiang · 2022 · Research Square
- Clinical efficacy and safety analysis of receiving PD-1 inhibitor-containing regimen in elderly patients with advanced gastric cancerJuanjuan Zhou, Yunlong Cai, Zhen Chen, Xiaomei Zhang, Xiaojun Xiang · 2023 · Research Square
- [Current Status and Prospect of PD-1/PD-L1 Immune Checkpoint Inhibitor Therapy in Elderly Patients with Advanced NSCLC].Yunye Mao, Shu Sheng, An Wang, Jinzhao Zhai, Xiangwei Ge, Di Lu, Jinliang Wang · 2024 · PubMed Central
- Characterizing immune profiles in hepatocellular carcinoma patients benefiting from pembrolizumab and lenvatinib using machine learningPei-Chang Lee, Po-Yu Li, Cheng-Yun Lee, Shian-Ren Lin, Chijung Wu, Y. Hung, Yu-Hua Chen, Jun-Wen Chan, Hsien-Chen Mon, Chieh-Ju Lee et al. · 2025 · BMC Cancer
- Additional file 6 of The effect of metformin on senescence of T lymphocytesYang, Jia, Liu, Hai-Cheng, Zhang, Jian-Qing, Zou, Jian-Yong, Zhang, Xin, Chen, Wo-Ming, Gu, Yong, Hong, Hai · 2024 · Figshare
- Additional file 2 of The effect of metformin on senescence of T lymphocytesYang, Jia, Liu, Hai-Cheng, Zhang, Jian-Qing, Zou, Jian-Yong, Zhang, Xin, Chen, Wo-Ming, Gu, Yong, Hong, Hai · 2024 · Figshare
- Additional file 3 of The effect of metformin on senescence of T lymphocytesYang, Jia, Liu, Hai-Cheng, Zhang, Jian-Qing, Zou, Jian-Yong, Zhang, Xin, Chen, Wo-Ming, Gu, Yong, Hong, Hai · 2024 · Figshare
- Additional file 1 of The effect of metformin on senescence of T lymphocytesYang, Jia, Liu, Hai-Cheng, Zhang, Jian-Qing, Zou, Jian-Yong, Zhang, Xin, Chen, Wo-Ming, Gu, Yong, Hong, Hai · 2023 · Figshare
- Additional file 5 of The effect of metformin on senescence of T lymphocytesYang, Jia, Liu, Hai-Cheng, Zhang, Jian-Qing, Zou, Jian-Yong, Zhang, Xin, Chen, Wo-Ming, Gu, Yong, Hong, Hai · 2024 · Figshare
- Additional file 4 of The effect of metformin on senescence of T lymphocytesYang, Jia, Liu, Hai-Cheng, Zhang, Jian-Qing, Zou, Jian-Yong, Zhang, Xin, Chen, Wo-Ming, Gu, Yong, Hong, Hai · 2024 · Figshare
- CD28 : nouvelles données sur un récepteur majeur de la costimulation lymphocytaire TStéphanie O. Morin · 2017 · theses.fr (ABES)
- Populations lymphocytaires circulantes exprimant PD-1 au cours des cancers bronchiques avancés, valeur prédictive de réponse aux inhibiteurs de PD-1/PD-L1Boris Duchemann · 2021 · theses.fr (ABES)
- CD8+ TEMRAs in AsthmaRichard Ramonell, Anuradha Ray · 2025 · ImmPort