Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food‐borne bacterial pathogens

Kortman, Guus A. M.; Mulder, Michelle L. M.; Richters, Thijs J. W.; Shanmugam, Nanda K. N.; Trebicka, Estela; Boekhorst, Jos; Timmerman, Harro M.; Roelofs, Rian; Wiegerinck, Erwin T.; Laarakkers, Coby M.; Swinkels, Dorine W.; Bolhuis, Albert; Cherayil, Bobby J.; Tjalsma, Harold

doi:10.1002/eji.201545642

Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food‐borne bacterial pathogens

Orally administrated iron is suspected to increase susceptibility to enteric infections among children in infection endemic regions. Here we investigated the effect of dietary iron on the pathology and local immune responses in intestinal infection models. Mice were held on iron‐deficient, normal…