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Cited by 80

The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.

Highlights in Biocatalysis – Historical Landmarks and Current Trends

Bornscheuer, U. T., Buchholz, K.·2005·Engineering in Life Sciences
DOI 10.1002/elsc.200520089
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Abstract

Biocatalysis has ancient roots, yet it is developing into a key tool for synthesis in a wide range of applications. Important events in the history of enzyme technology from the 19 th century onwards are highlighted. Considering the most relevant progress steps, the production of penicillanic acid and the impact of genetic engineering are traced in more detail. Applied biocatalysis has been defined as the application of a biocatalyst to achieve a desired conversion selectively, under controlled, mild conditions in a bioreactor. Biocatalysts are currently used to produce a wide range of products in the fields of food manufacture (such as bread, cheese, beer), fine chemicals (e.g., amino acids, vitamins), and pharmaceuticals (e.g., derivatives of antibiotics). They not only provide access to innovative products and processes, but also meet criteria of sustainability. In organic synthesis, recombinant technologies and biocatalysts have greatly widened the scope of application. Examples of current applications and processes are given. Recent developments and trends are presented as a survey, covering new methods for accessing biodiversity with new enzymes, directed evolution for improving enzymes, designed cells, and integrated downstream processing.

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Crossref · 10.1002/elsc.200520089

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Citations

Cites

Show all 88 references

Research works printed but not linked: 38

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Cited by

Metadata

Authors
Bornscheuer, U. T., & Buchholz, K.
Venue
Engineering in Life Sciences
Publisher
Wiley
Published
2005-08
Volume
5
Issue
4
Pages
309-323
ISSN
  • 1618-0240
  • 1618-2863
DOI
10.1002/elsc.200520089
Cited by
80
References
88
Language
en
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 29 d)

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