Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

Cited by (386)

Items 301–386 of 386

1. Nicotinamide riboside Induced Energy Stress and Metabolic Reprogramming in BEAS-2B Cells
   Everson Willian Fialho Cordeiro, Elisabete Leide Marzola, Ricardo Soei Maekawa, Matheus Relvas dos Santos, Lucas Gade Assunção, Mariana Pereira Massafera, Joseana de Oliveira, Thainá Gomes Cury Batista, Maria Cármen Oliveira Pinho de Sales, Silvya Stuchi Maria–Engler et al. · 2024 · Chemical Research in Toxicology
2. A unique red-emitting molecular rotor for high-fidelity visualizing and long-term tracking mitochondria
   Xinxin Zhang, Long Zhang, Fang Liu, Shuxin Hu, Quan Xu, Fei Li, Hui Li, Ge Zhang, Jingkun Xu · 2021 · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
3. Experimental therapy for mitochondrial diseases
   Carlo Fiore Viscomi, Massimo Zeviani · 2023 · Handbook of clinical neurology
4. Remission of social behavior impairment by oral administration of a precursor of NAD in CD157, but not in CD38, knockout mice
   Maria Gerasimenko, Haruhiro Higashida · 2023 · Frontiers in Immunology
5. Harnessing plant defense: Elicitors, hormones and immunity-driven production of medicinally valuable secondary metabolites
   Bismillah Mubeen, Shamas Murtaza, Sanabil Yaqoob, Afusat Yinka Aregbe, Turkson Antwi Boasiako, YuQing Xiong, YongKun Ma · 2025 · South African Journal of Botany
6. Mitochondrial Biogenesis and Dynamics in Health and Disease
   Juliane C. Campos, Luiz H. M. Bozi, Julio Cesar Batista Ferreira · 2021 · Springer eBooks
7. Applying the Airbrakes: Treating Mitochondrial Disease with Hypoxia
   Oliver M. Russell, Robert Neil Lightowlers, Douglass M. Turnbull · 2016 · Molecular Cell
8. Nutritional Regulation of Mitochondrial Function
   Goutham Vasam, Kimberly Reid, Yan Burelle, Keir J. Menzies · 2019 · Elsevier eBooks
9. Advances in Management of Mitochondrial Myopathies
   Athanasios Bangeas, Vasiliki Poulidou, Ioannis Liampas, Chrysoula Marogianni, Athina‐Maria Aloizou, Zisis Tsouris, Markos N. Sgantzos, Marianthi Arnaoutoglou, Dimitrios Petrou Bogdanos, Efthimios Dardiotis et al. · 2025 · International Journal of Molecular Sciences
10. Effect of Nicotinamide Adenine Dinucleotide on Heart Failure Caused by Ischemic Cardiomyopathy: A Randomized, Placebo-Controlled Trial
    Xiaofan Yu, Jie Xu, Jiaoyu Cao, Qizhi Xu, Hongwu Chen, Dongbiao Yu, Xunxia Yao, Kaibing Chen, Likun Ma · 2025 · American Journal of Cardiovascular Drugs
11. Short-term high-dose nicotinamide treatment across glaucoma subtypes reveals increased mtDNA content and minimal metabolomic change in blood
    Antoni Vallbona-Garcia, James R. Tribble, Simon T. Gustavsson, Birke J. Benedikter, Patrick J. Lindsey, Carroll A.B. Webers, Hubert J.M. Smeets, Gauti Jóhannesson, Theo G. M. F. Gorgels, Pete A. Williams · 2025 · Experimental Eye Research
12. A homologous stem cell therapy for obesity and its related metabolic disorders
    Dinh‐Toi Chu, Yang Tao · 2017 · Medical Hypotheses
13. Need for NAD+: Focus on Striated Muscle Laminopathies
    Déborah Cardoso, Antoine Muchir · 2020 · Cells
14. How to mitigate neurological and cardiac decompensation in Leigh syndrome: Can nicotinamide riboside be an answer?
    Alessandro Prigione, Carlo Fiore Viscomi · 2022 · Clinical and Translational Discovery
15. Ability of Nicotinamide Riboside to Prevent Muscle Fatigue of Barrows Subjected to a Performance Test
    Hanna M. Hennesy, Morgan E. Gravely, Daniela A Alambarrio, Savannah R. Brannen, Jonathan J. McDonald, Sarah A Devane, Kari K Turner, Alexander M. Stelzleni, Travis Gene O’Quinn, John Michael Gonzalez · 2024 · Metabolites
16. Effects of in ovo injection of nicotinamide riboside on high-yield broiler myogenesis
    Xiaoxing Xu, Hanna M. Alcocer, Morgan E. Gravely, Ashunti R. Jackson, John Michael Gonzalez · 2022 · Journal of Animal Science
17. Decrease of NAD+ Inhibits the Apoptosis of OLP T Cells via Inducing Mitochondrial Fission
    Zhuo-Yu Zhang, Fang Wang, Gang Zhou · 2025 · Journal of Inflammation Research
18. Protein Acetylation and NAD+ Homeostasis in Aging Muscle
    Li Li Ji · 2025 · Advances in experimental medicine and biology
19. Developing new treatments in partnership for primary mitochondrial disease: What does industry need from academics, and what do academics need from industry?
    Paul W. Thompson · 2020 · Journal of Inherited Metabolic Disease
20. Mutations in Assembly Factors Required for the Biogenesis of Mitochondrial Respiratory Chain
    Cristina Cerqua, Lisa Buson, Eva Trevisson · 2021 · Springer eBooks
21. NAD+ Boosting Strategies
    Jared Rice, Sofie Lautrup, Evandro Fei Fang · 2024 · Sub-cellular biochemistry/Subcellular biochemistry
22. Effects of Nicotinamide Riboside Supplementation on Postmortem Mitochondrial Functionality and Apoptotic Activation
    Zhu Chen, Luke A. Whitcomb, Adam J. Chicco, Morgan E. Gravely, Hanna M. Alcocer, Daniela A Alambarrio, John Michael Gonzalez, Colton L. Smith, Mahesh Narayanan Nair, Huey Yi Loh et al. · 2025 · Metabolites
23. Dietary restriction and Sirtuin 1 in metabolic health: connections and divergences
    Carles Cantó · 2015 · Proceedings of The Nutrition Society
24. Drug development for mitochondrial disease: recent progress, current challenges, and future prospects
    Paule Bénit, Manuel Schiff, Hélène Cwerman‐Thibault, Marisol Corral‐Debrinski, Pierre Rustin · 2015 · Expert Opinion on Orphan Drugs
25. Novel Mitochondrial Translation Optimizer-1 Mutations as a Cause of Hereditary Optic Neuropathy
    Emily Li, Valentina Emmanuele, Francine M. Testa, Cristiane Araújo Martins Moreno, Michio Hirano, Robert L. Lesser · 2019 · Journal of Neuro-Ophthalmology
26. Nicotinamide riboside alleviates Parkinson’s disease symptoms but downregulates dopamine metabolism upon lactacystin-induced proteostasis failure
    Giorgio Turconi, Farhan Alam, Tanima SenGupta, Sini Pirnes-Karhu, Soophie Olfat, Mark S. Schmidt, Kärt Mätlik, Ana Montaño-Rodriguez, Vladimir Heiskanen, Petteri T. Piepponen et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
27. Nicotinamide Riboside Supplementation Alleviates Heat Stress‐Induced Testicular Damage and Improves Semen Quality in Boars
    Wen Shen, Xiyao Luo, Xianyang Jin, Xiangyuan Ma, Xuemei Jiang, Chao Jin, Bin Feng, Lianqiang Che, Zhengfeng Fang, Shengyu Xu et al. · 2025 · Molecular Nutrition & Food Research
28. Huangjing Yangji Decoction ameliorates skeletal muscle aging and mitochondrial dysfunction via SIRT1/ATF5-mediated mitochondrial unfolded protein response
    Liming Zheng, Linghui Li, Zhize Liu, Chuanrui Sun, Da Wang, Xiao Peng, Kai Sun, Liguo Zhu, Xu Wei · 2025 · Phytomedicine
29. NAD+ and Sirt5 restore mitochondrial bioenergetics failure and improve locomotor defects caused by sucla2 mutations
    Joy Richard, Giulia Lizzo, Noélie Rochat, Adrien Jouary, Pedro TM Silva, Alice Parisi, Stefan Christen, Sofia Moco, Michael B. Orger, Philipp Gut · 2026 · JCI Insight
30. Therapies Approaches in Mitochondrial Diseases
    Valentina Emmanuele, Catarina Maria Quinzii, Michio Hirano · 2021 · Springer eBooks
31. Weaning difficulty after severe pneumonia in adult-onset mitochondrial myopathy with A3243G mutation in the mitochondrial tRNA gene: A case report
    Xiong Peng, Li-xiu Ma, Ce Xiao, Zhi-zhe Zhang, Min Zhu, Daojun Hong, Yian Zhan · 2023 · Heliyon
32. Vitamin B3 impairs reverse cholesterol transport in Apolipoprotein E-deficient mice
    Karen Alejandra Méndez‐Lara, David Santos, Núria Farré, Madalina Nicoleta Nan, Víctor Pallarès, Antonio Pérez, Núria Alonso, Joan Carles Escolá‐Gil, Francisco Blanco‐Vaca, Josep Julve · 2019 · Clínica e Investigación en Arteriosclerosis
33. Current biochemical treatments of mitochondrial respiratory chain disorders
    Robert A. Heaton, Lauren Elizabeth Millichap, Fatima Saleem, Jennifer Gannon, Gemma Begum, Iain Parry Hargreaves · 2019 · Expert Opinion on Orphan Drugs
34. Putative adjunct therapies to target mitochondrial dysfunction and oxidative stress in phenylketonuria, lysosomal storage disorders and peroxisomal disorders
    Nadia Turton, Tricia Rutherford, Dick H. J. Thijssen, Iain Parry Hargreaves · 2020 · Expert Opinion on Orphan Drugs
35. Niacin supplementation in a child with novel MTTN variant m.5670A>G causing early onset mitochondrial myopathy and NAD+ deficiency
    Juho Aaltio, Liliya Euro, Olli Tynninen, Hieu Vu, Min Ni, Ralph J. DeBerardinis, Anu Suomalainen, Pirjo Isohanni · 2024 · Neuromuscular Disorders
36. Mitophagy: an emerging therapeutic target in mitochondrial diseases
    Brígida R. Pinho, Michael R. Duchen, Jorge M. A. Oliveira · 2026 · Biochemical Journal
37. Mitochondrial disease: mechanisms, signalling, and therapeutic opportunities
    Samantha Corrà, Luke Young, Anthony L. Moore, Carlo Fiore Viscomi · 2026 · Free Radical Biology and Medicine
38. Nuclear‐Mitochondria Crosstalk in Senescent Adipose‐Derived Stem Cells
    Yixiang Zhang, Yawei Du, Shifeng Ling, Hanqi Wang, Jiahao He, Jiahong Li, Kaifeng Huo, Baikun Liu, Qingfeng Li, Jiao Wei et al. · 2026 · Smart Medicine
39. Mitochondrial Diseases
    Daniel G. Calame, Amy C. Goldstein · 2024 · Elsevier eBooks
40. Development of Treatments and Therapies to Target Mitochondrial Dysfunction
    Stephen B. Helliwell · 2016 · Springer eBooks
41. Novel NAD+ metabolomic technologies and their applications to Nicotinamide Riboside interventions
    Samuel A.J. Trammell, Michael E. Wright, Robert C. Piper, Charles Brenner, Diane C. Slusarski, Mary E. Wilson · 2016
42. Twinkle is not the mitochondrial DNA replicative helicase in C. elegans , but may have alternate mitochondrial functions
    Hope R. Henderson, Liliya Euro, Anu Suomalainen, Andrew G. Dillin · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
43. The effects of acute nicotinamide riboside supplementation on substrate utilisation and 5km time-trial performance
    Elizabeth Louise Gray · 2019 · University of Birmingham Institutional Research Archive (University of Birmingham)
44. The role of SIRT1 in skeletal muscle function and repair of older mice
    Matthew J. Myers · 2019 · The Research Repository @ WVU (West Virginia University)
45. De novo serine biosynthesis is protective in mitochondrial disease
    Christopher Benjamin Jackson, Anastasiia Marmyleva, Ryan Awadhpersad, Geoffray Monteuuis, Takayuki Mito, Nicola Zamboni, Takashi Tatsuta, Amy E. Vincent, Liya Wang, Thomas Langer et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
46. Lithocholic acid phenocopies rejuvenating and life-extending effects of calorie restriction
    Qi Qu, Yan Chen, Yu Wang, Shating Long, Weiche Wang, Heng-Ye Yang, Mengqi Li, Xiao Tian, Xiaoyan Wei, Yan‐Hui Liu et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
47. The effects of mitochondrial DNA mutagenesis on somatic stem cells and ageing
    Kati J. Ahlqvist · 2015 · Työväentutkimus Vuosikirja
48. Lack of Transferrin Receptor 1 in the Heart Causes Lethal Cardiomyopathy and Disruption of Mitophagy in Mice
    Wenjing Xu · 2015 · DukeSpace (Duke University)
49. NAD+ as a Pharmacological Tool to Boost Sirtuin Activity
    Riekelt H. Houtkooper · 2016 · Springer eBooks
50. Monitoring intracellular redox metabolism with genetically encoded fluorescent sensors
    Yuzheng Zhao, Yi YANG, Zhuo Zhang · 2017 · Scientia Sinica Vitae
51. Vitamin B3 salvage and NAD\(^+\) metabolism in skeletal muscle
    Rachel S. Fletcher · 2017 · University of Birmingham Institutional Research Archive (University of Birmingham)
52. NAD + Modulation
    Elena Katsyuba, Johan H. Auwerx · 2018 · Elsevier eBooks
53. Nutritional regulation of mitochondrial biogenic energy-sensing pathways in skeletal muscle following endurance exercise
    Ben Stocks · 2019 · University of Birmingham Institutional Research Archive (University of Birmingham)
54. Induction of the nicotinamide riboside kinase NAD + salvage pathway in skeletal myopathy of H6PDH KO mice
    Craig L. Doig, Agnieszka E. Zielinska, Rachel S. Fletcher, Lucy A. Oakey, Yasir Elhassan, Antje Garten, David Cartwright, Silke Heising, Ahmed Alsheri, David George Watson et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
55. Interventions to improve mitochondrial function in a mouse model of GRACILE syndrome, a complex III disorder
    Jayasimman Rajendran · 2019 · Työväentutkimus Vuosikirja
56. The Evolving Concept of Mitochondrial Dynamics in Heart: Interventional Opportunities
    Sivasailam Ashok, Mahalaxmi Ganjoo, Varghese Thomas Panicker, Vivek Velayudhan Pillai, Srinivas Gopala · 2019 · Springer eBooks
57. New therapeutics to modulate mitochondrial energy metabolism in neurodegenerative disorders
    Daniele Orsucci, Elena Caldarazzo Ienco, Gabriele Siciliano, Michelangelo Mancuso · 2020 · Elsevier eBooks
58. Stimulating the sir2-pgc-1ɑ axis rescues exercise capacity and mitochondrial respiration in Drosophila tafazzin mutants
    Deena Damschroder, Ruben Zapata Perez, Riekelt H. Houtkooper, Robert J. Wessells · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
59. Experimental Therapies
    Carlo Fiore Viscomi, Massimo Zeviani · 2019 · Springer eBooks
60. State of free-radical processes in the heart cell mitochondria under melanoma В16/F10 growth against the background of chronic neurogenic pain as comorbid pathology
    Elena Mikhaylovna Frantsiyants, Irina Valer'evna Neskubina, Alla Ivanovna Shikhlyarova, Ekaterina Igorevna Surikova, Lidiya Konstantinovna Trepitaki, Ludmila Anatolievna Nemashkalova, Valeriya Akhtyamovna Bandovkina, Irina Viktorovna Kaplieva, Lyudmila Ya Rozenko, Sergey N Dimitriadi · 2021 · Cardiometry
61. Leigh Syndrome
    Albert Zishen Lim, Robert McFarland · 2019 · Springer eBooks
62. Vitamin B3 impairs reverse cholesterol transport in Apolipoprotein E-deficient mice
    Karen Alejandra Méndez‐Lara, David Santos, Núria Farré, Madalina Nicoleta Nan, Víctor Pallarès, Antonio Pérez, Núria Alonso, Joan Carles Escolá‐Gil, Francisco Blanco‐Vaca, Josep Julve · 2019 · Clínica e Investigación en Arteriosclerosis (English Edition)
63. Nutraceuticals for targeting NAD+ to restore mitochondrial function
    Antje Garten, Gareth Geoffrey Lavery · 2022 · Elsevier eBooks
64. Metabolic precursors of nicotinamide adenine dinucleotide and the potential for their clinical use
    I. P. Sutsko, A. H. Shlyahtun, I. N. Semenenya · 2022 · Medical academic journal
65. The vitamin B 3 analogue nicotinamide riboside has only very minor effects on reducing muscle damage in mdx mice
    Tiberiu Loredan Stan, Davy v.d. Vijver, Ingrid E.C. Verhaart, Annemieke M Aartsma-Rus · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
66. Effects of nicotinamide riboside on stressed/fatigued barrow carcass characteristics and loin chop color stability
    Morgan E. Gravely, Hanna M. Hennesy, Daniela A Alambarrio, Olivia G. Ellis, Xiaoxing Xu, Alexander M. Stelzleni, John M. Gonzalez · 2025 · Meat Science
67. Coenzyme I and Skeletal Muscle Disorders
    Zhi Jiang, Li Luo, Yuanyuan Qin, Yadong Zhou, Feiyan Zhao · 2025 · Springer eBooks
68. NAD+ precursor treatment prevents cardiomyopathy but disrupts erythroid maturation in mitochondrial progeria
    Nahid Akthar Khan, Kati J. Ahlqvist, Swagat Pradhan, Juan C. Landoni, Christopher Benjamin Jackson, Aleksandra Zhaivoron, Riikka Kivelä, Liliya Euro, Anu Suomalainen · 2026 · Cell Reports
69. Biallelic FOXRED1 mutations cause infantile mitochondrial encephalopathy with complex I disassembly and basal ganglia degeneration
    Cunhui Pan, Ruowei Zhu, Xi‐Ping Huang, Haolin Duan, Tenghui Wu, Xiaole Wang, Ying Ding, Chen Chen, Fang He, Jing Peng et al. · 2025 · Mitochondrion
70. Additional file 1 of Mesenchymal stromal cells attenuate alveolar type 2 cells senescence through regulating NAMPT-mediated NAD metabolism
    Xiaofan Lai, Shaojie Huang, Sijia Lin, Lvya Pu, Wang, Yaqing, Lin, Yingying, Huang, Wenqi, Wang, Zhongxing · 2022 · Figshare
71. Additional file 1 of Rapamycin rescues mitochondrial dysfunction in cells carrying the m.8344A > G mutation in the mitochondrial tRNALys
    Mariantonietta Capristo, Valentina Del Dotto, Concetta Valentina Tropeano, Claudio Fiorini, Leonardo Caporali, Chiara La Morgia, Maria Lucia Valentino, Monica Montopoli, Valério Carelli, Alessandra Maresca · 2022 · Figshare
72. Exploring NAD+ Biology in Fish: From Cellular Metabolism to Ecological Adaptations and Aquaculture Strategies
    María Ángeles Esteban, Álvaro Sánchez-Ferrer · 2025 · Fishes
73. Ring Shift
    Gabro Gakely · 2026 · Annals of Rejuvenation Science
74. Pyrimidine and NAD salvage pathways : unexpected allies in the maintenance of genome stability
    Sandra Cunha Silveira · 2018 · theses.fr (ABES)
75. Effets de l’exercice et d’une modulation du métabolisme du NAD sur la fonction cardiaque et musculaire dans la cardiomyopathie dilatée
    Robin Deloux · 2018 · theses.fr (ABES)
76. Rôle de la PARylation sur l’apparition des troubles cardiovasculaires dans la progéria de Hutchinson-Gilford
    Déborah Cardoso · 2022 · theses.fr (ABES)
77. Finishing Barrow Skeletal Muscle Performance and Fatigue Response to Large-Dose Nicotinamide Riboside Supplementation
    Daniela A Alambarrio, Xiaohan Li, Siara S. Zedonek, Sophia E. Willis, Jordan N. Proctor, Faezeh Mozafari, Jarrod A. Call, Litzy E. Delgado, McKenna S. Doran, John M. Gonzalez · 2026 · Metabolites
78. Role of oxidative stress in the susceptibility to mitophagy of the skin fibroblasts and iPSC-derived neurons of patients with MERRF syndrome
    Yu-Ting Wu, Hui-Yi Tay, Hsiao-Hui Liao, Jung-Tse Yang, Yau‐Huei Wei · 2026 · Mitochondrion
79. Nicotinamide riboside prevents mitochondrial dysfunction in nemaline myopathy type 6
    R. Baelde, Leander A. Vonk, Edgar E. Nollet, R. Galli, Alexcia Fortes Monteiro, Sultan Bastu, Bornale Das, Michel van Weeghel, Bauke V. Schomakers, Kasper Tore Vinten et al. · 2026 · Human Molecular Genetics
80. Early life high-fat diet exposure modulates adult metabolic phenotypes in Drosophila
    Prachi Mishra, Gaurav Yadav, Shrishti Mitra, Raunak Gupta, Ranjan Kumar Sahu, Rogers Koboji, Kashyap Kumar Dubey, Ranjan Kumar Nanda, Vijendra Sharma, Pawel Michalak et al. · 2026 · iScience
81. Mitochondrial genome instability disrupts brown adipose tissue through pseudohypoxia-iron-NAD⁺ axis
    Serena S Ozturk, Swagat Pradhan, Madeleine H. Lackman, Lipsa Rani Panda, Aleksandra Zhaivoron, Markus Innilä, João S. Patrício, Lauren G. Zacharias, Thomas P. Mathews, Sinem Karaman et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
82. Mitophagy: a regulator and therapeutic target in cerebral ischemia/reperfusion injury
    Chalton Manengu, Zhen Tian, Huifeng Zhu · 2026 · Mitochondrion
83. Metabolic regulation of mitochondrial DNA (mtDNA) homeostasis
    Tânia Catarina Medeiros, Gaetano Calabrese · 2026 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
84. The Genetic and Epigenetic Mechanisms of mtDNA in Regulation of Inflammation and Metabolism
    Yulin Zhang, 郑言江, Hongyu Duan, Yifei Li · 2026 · The FASEB Journal
85. BindingDB Entry 50020322: Discovery of a First-in-Class CD38 Inhibitor for the Treatment of Mitochondrial Myopathy.
    BindingDB · 2024 · UC San Diego
86. BindingDB Entry 50013913: Discovery of 1-[2-(1-methyl-1H-pyrazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-3-(pyridin-4-ylmethyl)urea as a potent NAMPT (nicotinamide phosphoribosyltransferase) activator with attenuated CYP inhibition.
    BindingDB · 2022 · UC San Diego