Cited by 108Seed and Plant BiochemistryNatural Antidiabetic Agents StudiesFood composition and properties

Chia seeds (Salvia hispanica L.): A therapeutic weapon in metabolic disorders

Open access
Khalid, Waseem, Arshad, Muhammad Sajid, Aziz, Afifa, Rahim, Muhammad Abdul, Qaisrani, Tahira Batool, Afzal, Fareed, Ali, Anwar, Ranjha, Muhammad Modassar Ali Nawaz +2 more·2023·Food Science & Nutrition

Abstract

The growth of functional components containing agricultural foods is enhancing because these components aid the human body against different chronic diseases. Currently, chia seeds basically belong to the mint family and are edible seeds of Salvia hispanica. These seeds are composed of different functional components including fiber, polyphenols, antioxidants, omega‐3 fatty acid vitamins, minerals, and peptides. Besides, these seeds are also a good source of vegetable protein, unsaturated fat, carbohydrates, and ash. Chia seed components are helpful in cardiovascular disease (CVD) by reducing blood pressure, platelet aggregation, cholesterol, and oxidation. In GI‐tract‐related diseases like diabetes and constipation, chia fiber reduces the blood glucose level and provides bulk to stool. However, antioxidants and polyphenols are protected beta cells of the pancreas from inflammation. These components are protected from the cell damage of the different body parts, which can provide help in different types of cancer including breast, colorectal, liver, and pancreatic. Conclusively, some pervious studies approved that chia seed components are played important role in chronic diseases.

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  • Chia seeds contain omega-3 fatty acids, magnesium, potassium, calcium, and flavonoids (quercetin, chlorogenic acid, caffeic acid) that have been linked to reduced blood pressure.

    “They are rich in crucial fatty acids, particularly with a high omega-3 to omega-6 ratio, linked to reduced BP and a lower risk of CVD [43–45]. A 100-g serving of chia provides significant amounts of magnesium, potassium, and calcium, all potent vasodilators and vascular smooth muscle contraction inhibitors, effectively reducing BP [46–49]. Additionally, chia seeds contain flavonoids such as querc”

    From Effects of chia seed (Salvia hispanica L.) supplementation on cardiometabolic health in overweight subjects: a systematic review and meta-analysis of RCTs (2024) · cites this paper as [44]

    The Omega-3 fatty acid, Minerals, and Antioxidants sections (page unavailable) identify chia seeds as containing omega-3 fatty acids, magnesium, calcium, quercetin, chlorogenic acid, and caffeic acid. The Reduced the blood pressure section (page unavailable) reports that studies found lower blood pressure in patients with hypertension. Our copy does not establish that each listed nutrient or compound lowers blood pressure, and the searched passages do not identify potassium as a chia-seed mineral. (LLM, conf=0.88)

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References 140 · Cited by 108

Research works printed but not linked: 4

  1. Miller, D. D. (2017). Minerals (pp. 627– 679). CRC Press. 10.1201/9781315372914-11 · DOI
  2. Raven, P. H., Evert, R. F., & Eichhorn, S. E. (2005). Biology of plants (7th ed.). Macmillan, WH Freeman and Co.
  3. Scapin, G., Schmidt, M. M., Prestes, R. C., & Rosa, C. S. (2016). Phenolics compounds, flavonoids and antioxidant activity of chia seed extracts (Salvia hispanica) obtained by different extraction conditions. International Food Research Journal, 23(6), 2341– 2346.
  4. USDA. (2000). Dietary guidelines for Americans (5th ed.). Home and Garden Bull. No 232, 11

Authors
Khalid, W., Arshad, M. S., Aziz, A., Rahim, M. A., Qaisrani, T. B., Afzal, F., Ali, A., Ranjha, M. M. A. N., Khalid, M. Z., & Anjum, F. M.
Affiliations
  • Government College University, Faisalabad (PK)
  • Ghazi University (PK)
  • Central South University (CN)
  • University of Sargodha (PK)
  • Islamic Food and Nutrition Council of America IFANCA Halal Apex, Private Limited Faisalabad Pakistan
Corresponding author
Arshad, Muhammad Sajid
Venue
Food Science & Nutrition
Publisher
Wiley
Published
2022-12-15
Volume
11
Issue
1
Pages
3-16
ISSN
2048-7177 (ISSN-L)
OpenAlex
W4311777047
Cited by
108
References
140
Citations by year
2026: 32 · 2025: 33 · 2024: 27 · 2023: 16
FWCI
1.73
Type
journal article
Language
en
Open access
Locations
  • Food Science & Nutrition (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Informationszentrum Lebenswissenschaften (ZB MED) (submittedVersion, cc-by)
Funders
Government College University, Lahore
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Seed and Plant Biochemistry
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
  • Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
Keywords
Salvia hispanica, functional foods, metabolic disorders, cardiovascular disease, blood pressure, cholesterol, blood glucose, diabetes mellitus, constipation, dietary fiber, polyphenols, antioxidants, omega-3 fatty acids, cancer prevention, pancreatic beta cells, chronic disease

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