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Source connectivity analysis with MEG and EEG

Open access
Schoffelen, Jan‐Mathijs, Gross, Joachim·2009·Human Brain Mapping

Abstract

Interactions between functionally specialized brain regions are crucial for normal brain function. Magnetoencephalography (MEG) and electroencephalography (EEG) are techniques suited to capture these interactions, because they provide whole head measurements of brain activity in the millisecond range. More than one sensor picks up the activity of an underlying source. This field spread severely limits the utility of connectivity measures computed directly between sensor recordings. Consequentially, neuronal interactions should be studied on the level of the reconstructed sources. This article reviews several methods that have been applied to investigate interactions between brain regions in source space. We will mainly focus on the different measures used to quantify connectivity, and on the different strategies adopted to identify regions of interest. Despite various successful accounts of MEG and EEG source connectivity, caution with respect to the interpretation of the results is still warranted. This is due to the fact that effects of field spread can never be completely abolished in source space. However, in this very exciting and developing field of research this cautionary note should not discourage researchers from further investigation into the connectivity between neuronal sources. Hum Brain Mapp 2009. © 2009 Wiley‐Liss, Inc.

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Metadata

Authors
Schoffelen, J., & Gross, J.
Venue
Human Brain Mapping
Publisher
Wiley
Published
2009-02-23
Volume
30
Issue
6
Pages
1857-1865
ISSN
  • 1065-9471 (ISSN-L)
  • 1097-0193
OpenAlex
W2147899888
Cited by
850
References
49
FWCI
14.31
Type
journal article
Language
en
Open access
green

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Schoffelen, J., & Gross, J. (2009). Source connectivity analysis with MEG and EEG. Human Brain Mapping. https://doi.org/10.1002/hbm.20745

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