Telomerase Antagonists GRN163 and GRN163L Inhibit Tumor Growth and Increase Chemosensitivity of Human Hepatoma *

Djojosubroto, Meta W., Chin, Allison C., Go, Ning, Schaetzlein, Sonja, Manns, Michael P., Gryaznov, Sergei, Harley, Calvin B., Rudolph, Lenhard K.·2005·Hepatology
DOI 10.1002/hep.20822

Cited by (153)

Items 101–153 of 153

  1. Targeting Telomerase: Therapeutic Options for Cancer Treatment
    W. Nicol Keith, Alan E Bilsland · 2007 · Springer eBooks
  2. Computationally Designed Peptide Inhibitors of the Ubiquitin E3 Ligase SCFFbx4
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  3. A high-throughput assay for a human telomerase protein–human telomerase RNA interaction
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  4. Zinc protoporphyrin binding to telomerase complexes and inhibition of telomerase activity*
    Zhaowen Zhu, Huy Thien Tuan Tran, M. Meleah Mathahs, Brian D. Fink, John A. Albert, Thomas O. Moninger, Jeffery L. Meier, Ming Li, Warren N. Schmidt · 2021 · Pharmacology Research & Perspectives
  5. Population pharmacokinetics of imetelstat, a first‐in‐class oligonucleotide telomerase inhibitor
    Mario González‐Sales, Ashley L. Lennox, Fei Huang, Chandra Pamulapati, Ying Wan, Libo Sun, Tymara Berry, Melissa Kelly Behrs, Faye M. Feller, Peter N. Morcos · 2024 · CPT Pharmacometrics & Systems Pharmacology
  6. Targeting Telomerase in Hematologic Malignancy
    Michelle F. Maritz, Christine E. Napier, Victoria W. Wen, Karen L. MacKenzie · 2010 · Future Oncology
  7. Telomerase inhibitors as novel antitumor drugs
    Alexander I. Glukhov, L. V. Svinareva, E. S. Severin, В. И. Швец · 2011 · Applied Biochemistry and Microbiology
  8. Low Proarrhythmic Risk of Imetelstat, a Novel Oligonucleotide Telomerase Inhibitor: A Translational Analysis
    Ashley L. Lennox, Libo Sun, Fei Huang, Melissa Kelly Behrs, Robert Kleiman, Hongqi Xue, Neha Bhise, Ying Wan, Tymara Berry, Faye M. Feller et al. · 2025 · Clinical and Translational Science
  9. Managing telomerase and telomere dysfunction in acral melanoma
    Vishnu Sravan Bollu, Yu‐Chi Chen, Fan Zhang, Krishne Gowda, Shantu Amin, Arun Kumar Sharma, Todd D. Schell, Jiyue Zhu, Gavin P. Robertson · 2025 · Pharmacological Research
  10. The Role of Telomeres in Liver Disease
    Yoshiaki Sunami, Guido von Figura, Alexander Kleger, Pavel Strnad, Norbert Hüser, Daniel Hartmann · 2014 · Progress in molecular biology and translational science
  11. Telomeres and Telomerase in Humans
    Keiko Hiyama, Eiso Hiyama, Jerry W. Shay · 2009 · Humana Press eBooks
  12. Inhibition of Telomerase
    Christopher G. Tomlinson, Scott B. Cohen, Tracy M. Bryan · 2014 · Elsevier eBooks
  13. Cellular Senescence, Telomerase, and Cancer in Human Cells
    Phillip G. Smiraldo, Jun Ming Tang, Jerry W. Shay, Woodring Erik Wright · 2012
  14. Discovery of telomerase inhibitors: existing strategies and emerging innovations
    Lauren Kageler, Elisa Aquilanti · 2024 · Biochemical Society Transactions
  15. Mining Cellular Senescence for Drug Targets
    A. Bilsland, W. N. Keith · 2010 · Springer eBooks
  16. Role of Telomerase in Cancer Therapeutics
    Kyung H. Choi, Michel M. Ouellette · 2009 · Springer eBooks
  17. Variations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancer
    Steffen Heeg · 2015 · Pharmacogenomics and Personalized Medicine
  18. Epidemiology and Molecular Mechanisms of Hepatocarcinogenesis
    Hashem B. El‐Serag, André Lechel, K. Lenhard Rudolph · 2012 · Elsevier eBooks
  19. Telomeres and Telomerase in Ageing and Cancer
    Michel M. Ouellette · 2018 · Wiley eBooks
  20. Elimination of Cancer Stem Cells
    A. Sagrera, Jesús Pérez‐Losada, María Pérez-Caro, R. Jiménez, Isidro Sánchez-Garcı́a, César Cobaleda · 2009 · Springer eBooks
  21. Novel Therapeutic Targets for Hepatocellular Carcinoma Treatment
    Yangchao Chen, Chi Han · 2012 · InTech eBooks
  22. New Therapeutic Strategies for the Treatment of Brain Tumor
    Rintaro Hashizume · 2011 · InTech eBooks
  23. Cancer, Senescence, and Aging: Translation from Basic Research to Clinics
    Matilde Esther LLeonart, Amancio Carnero, Rosanna Paciucci, Zhao‐Qi Wang, Noam Shomron · 2011 · Journal of Aging Research
  24. Telomere Biology in T Cells: An Important Brake on the Road of Their Life Span?
    Alexander Röth, Gabriela Maria Baerlocher · 2009 · Clinical Leukemia
  25. New Oligonucleotide 2′-O-Alkyl N3′→P5′ (Thio)-Phosphoramidates as Potent Antisense Agents: Physicochemical Properties and Biological Activity
    Saúl Martínez‐Montero, Vivek K. Rajwanshi, Rajendra K. Pandey, N. Tilani S. De Costa, Jin Hong, Leonid N. Beigelman, Sergei M Gryaznov, Soheil Pourshahian · 2023 · Nucleic Acid Therapeutics
  26. Regulation of the Liver Cell Mass
    Nisar P. Malek, K. Lenhard Rudolph, Anna Mae Diehl · 2007 · Wiley eBooks
  27. Telomeres and Aging, Cancer, and Hepatic Fibrosis
    Hans Ludger Tillmann, Ruben R. Plentz, Yvonne Begus‐Nahrmann, A Lechel, K. Lenhard Rudolph · 2009 · Wiley eBooks
  28. Regulation der Telomerase in Mammakarzinomen eines bitransgenen Mausmodells [Mus musculus (Linnaeus, 1758)]
    Britta Wittek · 2007
  29. Growth factor-mediated telomerase activity in ovarian cancer cells
    Yira Bermudez · 2007 · Digital Commons - University of South Florida (University of South Florida)
  30. Telomerase: target for cancer treatment
    Jerry W. Shay, Woodring Erik Wright · 2013 · Cambridge University Press eBooks
  31. Telomere Dysfunction and the DNA Damage Response
    Malissa C. Diehl, Lynne W. Elmore, Shawn E. Holt · 2009 · Humana Press eBooks
  32. Investigations of the Telomerase Template Antagonist GRN163L and Implications for Augmenting Breast Cancer Therapy
    Erin M. Goldblatt · 2009
  33. Complexes of telomeric oligonucleotides with the PGEk protein vector: Internalization by target cells and antiproliferative activity
    Galina A. Posypanova, Andrey N. Chuvilin, Natashe Kireeva, E. S. Severin, Galina E. Pozmogova · 2008 · Molecular Biology
  34. Telomeres, Telomerase, and DNA Damage Response in Cancer Therapy
    Raina Tamakawa, Helen B. Fleisig, Judy M.Y. Wong · 2012 · Springer eBooks
  35. Aus der I. Medizinischen Klinik und Poliklinik des Zentrums für Innere Medizin des Universitätsklinikums Hamburg-Eppendorf
    Ansgar Wilhelm Lohse · 2008
  36. Telomeres and the End Replication Problem
    Tracy M. Bryan · 2009 · Royal Society of Chemistry eBooks
  37. Consequences of telomerase inhibition and telomere dysfunction in BRCA1 mutant cancer cells
    Elizabeth A. Phipps · 2014 · IUScholarWorks (Indiana University)
  38. Cancer Cell Immortality: Targeting Telomerase
    İlgen Mender, Z. Günnur Dikmen, Woodring Erik Wright, Jerry W. Shay · 2017 · Wiley eBooks
  39. Chemical and Pharmacological Modulation of Telomerase
    Joana Soares · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  40. Cancer Stem Cells as Therapeutic Targets for Gastrointestinal Cancers
    Jyothi Priya Mandala, Srinivas Pittala, Gowru Srivani · 2020 · Springer eBooks
  41. Activity and Regulation of Telomerase in Malignant Cells
    Anna Lindkvist · 2006 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
  42. Therapeutic Targets and Drugs I: Telomerase and Telomerase Inhibitors
    Brittney‐Shea Herbert, Erin M. Goldblatt · 2009 · Humana Press eBooks
  43. Cancer Cell Immortality: Targeting Telomerase and Telomeres
    İlgen Mender, Z. Günnur Dikmen, Jerry W. Shay · 2022 · Wiley eBooks
  44. Liver Cancer: Interdisciplinary Approach
    Haiwei Zhang, Juan Zhao, Wei Yang, Zheng Li, Li Gong, Yongsheng Li · 2022 · Interdisciplinary cancer research
  45. Data from The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel
    Erin M. Goldblatt, Erin R. Gentry, Melanie J. Fox, Sergei M Gryaznov, Changyu Shen, Brittney‐Shea Herbert · 2023
  46. Data from The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel
    Erin M. Goldblatt, Erin R. Gentry, Melanie J. Fox, Sergei M Gryaznov, Changyu Shen, Brittney‐Shea Herbert · 2023
  47. Data from Telomerase Template Antagonist GRN163L Disrupts Telomere Maintenance, Tumor Growth, and Metastasis of Breast Cancer
    Amelia E. Hochreiter, Hongling Xiao, Erin M. Goldblatt, Sergei M Gryaznov, Kathy D. Miller, Sunil Badve, George W. Sledge, Brittney‐Shea Herbert · 2023
  48. Broad-spectrum antitumor analysis of the telomerase activity inhibitor TPCH derived from the human constitutively expressed protein LPTS/PinX1
    Hongchang Zhou, Xiaoying Zhang, Yao Wang, Yongqiang Wu, Lingling Wang, Hu Chen, Ting Zhang, Hui Zhang, Dian You, Mengli Zhao et al. · 2025 · Frontiers in Oncology
  49. Déprotection et raccourcissement télomériques dans le carcinome hépatocellulaire
    Lalla Manale El Idrissi · 2013 · theses.fr (ABES)
  50. Des outils moléculaires toujours plus multifonctionnels pour l’étude de structures alternatives d’acides nucléiques.
    Francesco Rota Sperti · 2022
  51. BindingDB Entry 50043794: Telomere maintenance as a target for drug discovery.
    BindingDB · 2014 · UC San Diego
  52. BindingDB Entry 50049060: Targeting telomerase with radiolabeled inhibitors.
    BindingDB · 2019 · UC San Diego
  53. Senescence Signatures of Human Hematopoietic Stem Cells
    Stefan Zimmermann, Uwe M. Martens · 2007 · Springer eBooks