The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis†
Perugorria, Maria J., Latasa, M. Ujue, Nicou, Alexandra, Cartagena‐Lirola, Hugo, Castillo, Josefa, Goñi, Saioa, Vespasiani‐Gentilucci, Umberto, Zagami, Maria G. +4 more·2008·Hepatology
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Items 101–151 of 151
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- Inflammatory monocyte-derived amphiregulin mediates intestinal fibrosis in Crohn’s disease by activating PI3K/AKTShu Wang, Lu Wang, Junjie Lin, Mingyuan Wang, Jiajia Li, Qiong Guo, Chunhua Jiao, Nana Tang, Jingjing Ma, Hongjie Zhang et al. · 2025 · Mucosal Immunology
- Activation of epidermal growth factor receptor gene is involved in transforming growth factor-β-mediated fibronectin expression in a chondrocyte progenitor cell lineInoue · 2010 · International Journal of Molecular Medicine
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- The hepatocyte epidermal growth factor receptor ( EGFR ) pathway regulates the cellular interactome within the liver fibrotic nicheEster Gonzalez‐Sanchez, Javier Vaquero, Daniel Caballero‐Díaz, Jan Grzelak, Noel P. Fusté, Esther Bertrán, Josep Amengual, Juan García‐Sáez, Beatriz Martín‐Mur, Marta Ortova Gut et al. · 2024 · The Journal of Pathology
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- Efficacy of epidermal growth factor in suppressing inflammation and proliferation in pterygial fibroblasts through interactions with microenvironmental M1 macrophagesSoo Jin Lee, Ahra Koh, Seung Hyeun Lee, Kyoung Woo Kim · 2024 · Scientific Reports
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- Amphiregulin in Fibrotic Diseases and CancerTae Rim Kim, Beomseok Son, Chun Geun Lee, Han-Oh Park · 2025 · International Journal of Molecular Sciences
- Potential role of epidermal growth factor receptors (EGFR) signaling in the pathogenesis and management of hepatocellular carcinomaSamah Saleh Ahmed Al-Awadhi, Prakash Patil, Praveenkumar Shetty, Padma K Shetty, Reshma Arun Shetty, Vijith Vittal Shetty · 2025 · Bioimpacts
- Potential therapeutic target of EGF on bile duct ligation model and biliary atresia childrenQipeng Zheng, Mengdi Li, Lingzhi Chen, Cong Zhang, Yilin Zhao, Gengxin Liu, Fang Yang, Jianghua Zhan · 2023 · Pediatric Research
- Mechanisms of main components in Curcuma longa L. on hepatic fibrosis based on network pharmacology and molecular docking: A reviewQiang Han, Jiahui Zhu, Peng Zhang · 2023 · Medicine
- Hepatocyte-specific Epidermal Growth Factor Receptor Deletion Promotes Fibrosis but has no Effect on Steatosis in Fast-food Diet Model of Metabolic Dysfunction-associated Steatotic Liver DiseaseShehnaz Bano, Matthew A. Copeland, John W. Stoops, Anne V. Orr, Siddhi Jain, Shirish Paranjpe, Raja Gopal Reddy Mooli, Sadeesh Kumar Ramakrishnan, Joseph D. Locker, Wendy M. Mars et al. · 2024 · Cellular and Molecular Gastroenterology and Hepatology
- Carfilzomib shows therapeutic potential for reduction of liver fibrosis by targeting hepatic stellate cell activationAyana Fujiwara, Keisuke Takemura, Anna Tanaka, Misaki Matsumoto, Masato Katsuyama, Takeshi Okanoue, Kanji Yamaguchi, Yoshito Itoh, Kazumi Iwata, Kikuko Amagase et al. · 2024 · Scientific Reports
- Overexpression of Heparin-Binding Epidermal Growth Factor-Like Growth Factor Mediates Liver Fibrosis in Transgenic MiceYongze Guo, Qian Ding, Lei Chen, Chenguang Ji, Huiyao Hao, Jia Wang, Wei Qi, Xiao‐Li Xie, Junji Ma, Aidi Li et al. · 2017 · The American Journal of the Medical Sciences
- Amphiregulin alleviated concanavalin A-induced acute liver injury via IL-22Qili Wu, Jingrou Chen, Xiaoli Hu, Yinhong Zhu, Shu‐Juan Xie, Chang You Wu, Zhong Pei, Shiqiu Xiong, Yanwen Peng · 2020 · Immunopharmacology and Immunotoxicology
- The Immune Microenvironment: New Therapeutic Implications in Organ FibrosisXiangqi Chen, Chuan Fen Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He · 2025 · Advanced Science
- Amphiregulin: a potential therapeutic target for tissue fibrosisM.H. Wang, Jian Liu, Shiliang Li, Miaomiao Zheng, R.Y. Qu, M. Xiang · 2025 · Trends in Pharmacological Sciences
- Clinical significance of amphiregulin in patients with chronic kidney diseaseYuki Osakabe, Yoshinori Taniguchi, Kazu Hamada‐Ode, Yoshiko Shimamura, Satoshi Inotani, Hirofumi Nishikawa, Tatsuki Matsumoto, Taro Horino, Shimpei Fujimoto, Yoshio Terada · 2024 · Clinical and Experimental Nephrology
- Animal Models of Cutaneous and Hepatic FibrosisGideon Piers Smith · 2011 · Progress in molecular biology and translational science
- Targeted elimination of activated hepatic stellate cells by an anti‐epidermal growth factor‐receptor single chain fragment variable antibody‐tumor necrosis factor‐related apoptosis‐inducing ligand (scFv425‐sTRAIL)Mohammad Arabpour, Klaas Poelstra, Wijnand Helfrich, Edwin Bremer, Hidde J. Haisma · 2014 · The Journal of Gene Medicine
- Research progress of epidermal growth factor receptor in metabolic dysfunction‐associated steatotic liver disease and related diseasesZiwen Wang, Ze Jin, Zhi-fan Xiong · 2025 · Diabetes Obesity and Metabolism
- Genistein Produces Hepatoprotection through Modulating EGFR Expression and Phosphorylation in Experimental FibrosisRodriguez Fragoso L, Alvarez Ayala E · 2016 · Journal of Liver
- DNA-damaging chemotherapy reshapes cardiac-resident macrophage composition and functionRuijun He, Farid F. Kadyrov, Andrew L. Koenig, Pan Ma, Andrea L. Bredemeyer, Mandy M. Chan, Joel D. Schilling, Shibali Das, Joseph S. Lagas, Daniel Kreisel et al. · 2026 · Science Immunology
- Animal Models of Fibrosis in Human DiseaseGideon Piers Smith · 2013 · Elsevier eBooks
- The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic InflammationKorkmaz, Rabia Ülkü, Omony, Jimmy, Tan, Xiaomei, Klotz, Markus, Dragunas, Guilherme, Chen, Sirui, Shankhwar, Soni, Ertüz, Zeynep, Müller, Christoph, Ragab, Mohab et al. · 2026 · Allergy
- Amphiregulin-producing TH2 cells facilitate esophageal fibrosis of eosinophilic esophagitisTatsuya Kaneko, Chiaki Iwamura, Masahiro Kiuchi, Akane Kurosugi, Miki Onoue, Tomoaki Matsumura, Tetsuhiro Chiba, Toshinori Nakayama, Naoya Kato, Kiyoshi Hirahara · 2024 · Journal of Allergy and Clinical Immunology Global
- The novel protein C9orf116 promotes rat liver cell line BRL-3A proliferationChunyan Zhang, Cuifang Chang, Weiming Zhao, Hang Gao, Qiwen Wang, Deming Li, Fuchun Zhang, Shifu Zhang, Cunshuan Xu · 2017 · PLoS ONE
- AREG (amphiregulin (schwannoma-derived growth factor))Carmen Berasain, MA Avila · 2011 · Atlas of Genetics and Cytogenetics in Oncology and Haematology
- Pharmacological Impacts of Mucopolysacccharide Polysulfates in the Epidermis Involves Inhibition of Amphiregulin‐Mediated Signals in KeratinocytesRyo Hirase, Tomoyuki Fujita, Tomohiro Miyai, Hiroshi Kawasaki, Haruhiko Koseki · 2024 · Experimental Dermatology
- The effect of amphiregulin on equine endometrial fibroblasts: in vitro responses of fibroblast derived from non-fibrotic and fibrotic endometriumAnna Wójtowicz, Agnieszka Sadowska, K.K. Piotrowska-Tomala, Anna Zuzanna Szóstek-Mioduchowska · 2025 · Reproductive Biology
- Signaling Pathways as Potential Therapeutic Targets in HepatocarcinogenesisYeliz Yılmaz, Aysim Güneş, Hande Topel, Neşe Atabey · 2017 · Journal of Gastrointestinal Cancer
- Tissue Remodeling and Repair During Type 2 InflammationAlexander J. Chan, Jessica C. Jang, Meera Goh Nair · 2015 · Springer eBooks
- EASL Recognition Awardee 2013Mario Strazzabosco · 2013 · Journal of Hepatology
- Papel de SLU7 en la regulación epigenética de la expresión génica: control de la estabilidad de DNMT1 y la metilación del DNAMiriam Recalde · 2022
- Pro-inflammatory responses in BALB/c and C57BL/6 mice and the role of the Nrf2-amphiregulin axis in ventilator induced lung injuryStephanie Siegl, Stefan Uhlig · 2013 · RWTH Publications (RWTH Aachen)
- Nuevos mecanismos en la defensa natural del hígado frente a la lesiónCarmen Berasain Lasarte, José Castillo, María Íñiguez, Matias Antonio Avila, Maria Ujue Latasa, Saioa Goñi, Jesús Prìeto, Maria Jesus Perugorria · 2009 · Gastroenterología y Hepatología
- A macrophage-pericyte axis directs tissue restoration via Amphiregulin-induced TGFβ activationRucha V. Modak, Carlos M. Minutti, Felicity Macdonald, Fengqi Li, Danielle J. Smyth, David A. Dorward, Natalie F. Blair, Connor Husovsky, Andrew Muir, Ross Dobie et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- The Characteristics of Peripheral Blood Mononuclear Cells in Takayasu Arteritis by Single Cell RNA SequencingQing Gao, Jinge Yu, Zuoguan Chen, Yongpeng Diao, Yuqing Miao, Yin Jinfeng, Junnan Jia, Weimin Li, Yongjun Li · 2021
- Papel de SLU7 en la diferenciación hepática y en la protección del hígado frente al daño: regulación de HNF4AMaría Gárate‐Rascón · 2022
- Comprehensive characterization of pyroptosis reveals novel molecular typing of biliary atresia as well as contributes to precise treatmentTengfei Li, Qipeng Zheng, Xueting Wang, Qianhui Yang, Mengdi Li, Xiaodan Xu, Yilin Zhao, Fangyuan Zhao, Ruifeng Zhang, Zhiru Wang et al. · 2023 · Research Square
- THE ROLE OF THE PRO-FIBROTIC GROWTH FACTOR AMPHIREGULIN IN RADIATION CYSTITISBernadette M. M. Zwaans, S Mota, Elijah P. Ward, Sarah N. Bartolone, Michael B. Chancellor · 2023 · Continence
- Dynamic dual regulation of amphiregulin in liver pathophysiology: balancing regeneration and disease progression via the EGFR axisYi-li Wang, De-Jiang Zhou, Qiong Wang, Ye Zhang, Wen-Jing Yang, Wen Tan, Hao-Yu Wang, Xiao-Wan Chen, San-Qiang Li · 2026 · Frontiers in Medicine
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- Milk fat globule EGF and factor V/VIII domain containing (MFGE8) as a novel player in equine endometrial fibrosisElena Zu Klampen, Gregor Neufeld, Claudia Klein · 2026 · Scientific Reports
- The Epidermal Growth Factor Receptor (EGFR) as a means of neuro-immune cross-conversationKatharina Gryksa, Maria Chiara Sibilia, Veit Rothhammer, Adrian Liston, Dietmar M. W. Zaiss · 2026 · Journal of Neuroinflammation
- Amphiregulin as a central dynamic network biomarker in inhaled polyhexamethylene guanidine triggered pulmonary fibrosisJianzhong Zhang, Xin Li, Yuxin Ma, Wanjun Zhang, Zihao Han, Yanting Li, Jiayin Sun, Siqi Wang, Wei Han, Jing Liu et al. · 2026 · Journal of Hazardous Materials