PNPLA3 Variants Specifically Confer Increased Risk for Histologic Nonalcoholic Fatty Liver Disease But Not Metabolic Disease†,‡

Cited by (362)

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  3. Diabetes and Liver Disease
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  9. Understanding the Role of PNPLA3 Genetic Variants in Patients with Chronic Hepatitis C Infection
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  10. Which Method is Superior in the Diagnosis of Nonalcoholic Fatty Liver and Steatohepatatis in Children?
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  11. Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan Takuya KitamotoAya KitamotoMasato YonedaHideyuki HyogoHidenori Ochi • Takahiro NakamuraHajime TeranishiSeiho MizusawaTakato UenoKazuaki Chayama • Atsushi NakajimaKazuwa NakaoAkihiro SekineKikuko Hotta
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  12. Pediatric Nonalcoholic Fatty Liver Disease
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  13. Role of molecular genetic factors in pathogenesis and diagnosis of non-alcoholic fatty liver disease (literature review and own data)
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  14. Impact of Host Genetic Variants on Natural History and Treatment of Hepatitis C Virus Infection
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  15. The reversibility of type 2 diabetes
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  16. Non‐alcoholic Fatty Liver Disease
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  17. Clinical Genomics of NAFLD
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  18. Hepatic Lipid Droplets in Liver Function and Disease
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  19. Therapeutic Approaches for Nonalcoholic Steatohepatitis ( NASH )
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  20. Frequency of I148M Polymorphism of the PNPLA3 Gene Associated with a Risk of Steatosis and Liver Fibrosis in Residents of the Republic of Sakha (Yakutia)
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  21. Letter to the Editor: Association between birth weight, preterm birth, and nonalcoholic fatty liver disease in a community-based cohort
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  22. A genome-wide ATLAS of liver chromatin accessibility reveals that sex dictates diet-induced nucleosome dynamics
    Zhengyi Zhang, Vivien Su, Carrie B. Wiese, Lijing Cheng, Dan Wang, Ya Cui, Aneesh S. Kallapur, Jason Kim, Xiaohui Wu, Peter H. Tran et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  23. Genetic Predisposition to NAFLD and NASH: Implications for Pathogenesis, Diagnosis, Prevention, and Management
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  24. Non-invasive elastography-based study in patients with chronic liver diseases identifies variant adiponutrin as common fibrosis risk factor
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  27. A Functional Polymorphism in the Epidermal Growth Factor Gene Independently Predicts Clinical Decompensation in HCV-Related Cirrhosis
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  28. Nonalcoholic Fatty Liver Disease: is It All in the Genes?
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  29. MOLECULAR GENETICS OF PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING 3 AND CHRONIC LIVER DISEASE
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  30. Genetic Pleiotropies of Obesity
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  31. PNPLA3 Polymorphisms and Liver Aminotransferase Levels in a Mexican
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  32. Central JSM Gastroenterology and Hepatology
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  33. Is NAFLD different in absence of metabolic syndrome?
    Yusuf Nadir Yilmaz · 2016
  34. Etiology and Pathogenesis of Hepatocellular Carcinoma: Hepatocellular Carcinoma Associated with Inborn Errors of Metabolism and Hepatobiliary Malformations
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  35. PNPLA3 Polymorphism and Nonalcoholic Fatty Liver Disease
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  36. The Genetic Mechanisms Underlying Human Obesity
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  37. The Role of Bacterial Products and Intestinal Microbiota in Non-Alcoholic Fatty Liver Disease
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  38. An in vitro model to study the adipose tissue toll-like receptor -mediated effects of gut microbiota on non-alcoholic fatty liver disease development
    Sakari Välimäki · 2017 · Jyväskylä University Digital Archive (University of Jyväskylä)
  39. The rs738409 (I148M) Variant of the PNPLA3 Gene and Type 2 Diabetes in Yakutia
    Liubov A. Sydykova, Yakutsk, the Republic of Sakha (Yakutia), Russia, Х.А. Куртанов, Natalia Borisova, Nadejda Pavlova, К.М. Степанов, Sardana V. Markova, Albert Makarov, Sardana Alekseeva, Uliana I. Antipina · 2018 · International Journal of Biomedicine
  40. Effects of the PNPLA3–SNP rs738409 on Serum Transaminase levels are modified by body mass index and alcohol consumption
    Peter J. Meffert · 2018 · Biometrics & Biostatistics International Journal
  41. Role of ceacam1 and shp1 in the regulation of insulin sensitivity and hepatic glucose and lipid metabolism
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  42. Reply to Drs Mantovani and Zusi
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  45. Diabetes and Liver Disease
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  46. Diabetes and Liver Disease
    Robert P. Hirten, Henry Charles Bodenheimer, Douglas Meyer, David Bernstein · 2017 · Springer eBooks
  47. Diabetes and Liver Disease
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  48. PNPLA3/adiponutrin I148M gene variant in nonalcoholic fatty liver disease in Egyptian children and adolescents
    Dina S. Ata, Mohy A.E. Awad, Manal Abd El-Wahed Eid, Khaled I. ElShafey, Ola Taha · 2021 · Alexandria Journal of Pediatrics
  49. Etiology and Pathogenesis of Hepatocellular Carcinoma: Hepatocellular Carcinoma Associated with Inborn Errors of Metabolism and Hepatobiliary Malformations
    Arthur Zimmermann · 2016 · Springer eBooks
  50. PNPLA3 Polymorphism and Nonalcoholic Fatty Liver Disease
    Olena Vadymivna Kolesnikova, Valeriya Danilovna Nemtsova, Rajkumar Rajendram · 2017 · Biomarkers in disease
  51. Reply:
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  52. Pathophysiologie: Genetik
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  53. In Silico and In Vitro Analyses of PNPLA3 rs738409 C>G Polymorphism in Patients With Non-alcoholic Fatty Liver Disease
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  54. Global epidemiology of NAFLD
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  56. Prevalence and effect of PNPLA3 and TM6SF2 gene polymorphism on the course of non-alcoholic fatty liver disease
    N. S. Branovitskaya, А. Л. Калинин, А. А. Ковалев, M. N. Yatsuk, E. A. Lipskaya · 2025 · Health and Ecology Issues
  57. Papel de las lipasas metabólicas y la lipotoxicidad en el desarrollo de esteatosis hepática y esteatohepatitis no alcohólica
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  58. Additional file 1 of Factors associated with elevated alanine aminotransferase in employees of a German chemical company: results of a large cross-sectional study
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  59. Integrated chromatin and transcriptomic profiling reveals sex-specific mechanisms of gene regulation in hepatic nutrient responses
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  62. Pnpla3/Adiponutrin Deficiency in Mice Does Not Contribute to Steatohepatitis, Fibrosis or Cholestatic Liver Injury
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