Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk

Mátrai, Janka, Cantore, Alessio, Bartholomae, Cynthia C., Annoni, Andrea, Wang, Wei, Acosta-Sanchez, Abel, Samara-Kuko, Ermira, De Waele, Liesbeth +12 more·2011·Hepatology

Cited by (139)

Items 101–139 of 139

  1. Improving the Transduction of Bone Marrow–Derived Cells with an Integrase-Defective Lentiviral Vector
    S. Louise Pay, Xiaoping Qi, Jeffrey F. Willard, Juliana Aparecida Preto de Godoy, Kavya Sankhavaram, Ranier Horton, Sayak K. Mitter, Judith Quigley, Lung‐Ji Chang, Maria B. Grant et al. · 2017 · Human Gene Therapy Methods
  2. Anti-CD20 as the B-Cell Targeting Agent in a Combined Therapy to Modulate Anti-Factor VIII Immune Responses in Hemophilia a Inhibitor Mice
    Chao-Lien Liu, Peiqing Ye, Jacqueline Lin, Cherié L. Butts, Carol H. Miao · 2014 · Frontiers in Immunology
  3. Differences in vector-genome processing and illegitimate integration of non-integrating lentiviral vectors
    Aaron Shaw, Guiandre L. Joseph, Aparna C. Jasti, Lakshmi Sastry, Scott R. Witting, Kenneth G. Cornetta · 2016 · Gene Therapy
  4. Liver targeted gene therapy: Insights into emerging therapies
    Carlos G. Moscoso, Clifford J. Steer · 2019 · Drug Discovery Today Technologies
  5. Targeted Lentiviral Vectors: Current Applications and Future Potential
    Cleo Goyvaerts, Thérèse Liechtenstein, Christopher Bricogne, David Escors, Karine Breckpot · 2013 · InTech eBooks
  6. Gene therapy for hemophilia
    Paul Edward Monahan, Tong Gui · 2013 · Current Opinion in Hematology
  7. Lentivirus-Induced Dendritic Cells (iDC) for Immune-Regenerative Therapies in Cancer and Stem Cell Transplantation
    Renata Stripecke · 2014 · Biomedicines
  8. Integrase-Defective Lentiviral Vectors for Delivery of Monoclonal Antibodies against Influenza
    Michelini, Zuleika, Minkoff, Judith M., Yang, Jianjun, Negri, Donatella, Cara, Andrea, Hanson, Brendon J., Salvatore, Mirella · 2020 · Viruses
  9. Editing T cell repertoire by thymic epithelial cell-directed gene transfer abrogates risk of type 1 diabetes development
    Fabio Russo, Eliana Ruggiero, Rosalia Curto, Laura Passeri, Francesca Sanvito, Ileana Bortolomai, ANNA MARIA VILLA, Silvia Gregori, Andrea Annoni · 2022 · Molecular Therapy — Methods & Clinical Development
  10. HIV-Derived Vectors for Gene Therapy Targeting Dendritic Cells
    Maura Maria Rossetti, Mariangela Cavarelli, Silvia Gregori, Gabriella Scarlatti · 2012 · Advances in experimental medicine and biology
  11. DDC-Promoter-Driven Chemogenetic Activation of SNpc Dopaminergic Neurons Alleviates Parkinsonian Motor Symptoms
    Dong-Chan Seo, Yeon Ha Ju, Jin-Ju Seo, Soo‐Jin Oh, Changjoon Justin Lee, Seung Eun Lee, Min‐Ho Nam · 2023 · International Journal of Molecular Sciences
  12. Target-Seq: Single Workflow for Detection of Genome Integration Site, DNA Translocation and Off-Target Events
    Pei‐Zhong Tang, Ding Bo, Christopher Reyes, David Papp, Jason Potter · 2023 · BioTechniques
  13. Optimizing Delivery and Expression of Designer Nucleases for Genome Engineering
    Marinee Chuah, Thierry VandenDriessche · 2013 · Human Gene Therapy Methods
  14. Gene Therapy for Inherited Liver Disease: To Add or to Edit
    Yue Chen, Niek P. van Til, Piter J. Bosma · 2024 · International Journal of Molecular Sciences
  15. Identification of hepatocyte-primed cholangiocytes in the homeostatic liver by in vivo lentiviral gene transfer to mice and non-human primates
    Michela Milani, Francesco Starinieri, Anna Fabiano, Stefano Beretta, Tiziana Plati, Cesare Canepari, Mauro Biffi, Fabio Russo, Valeria Berno, Rossana Norata et al. · 2025 · Cell Reports
  16. Erosion of the pump mechanism of an inflatable penile prosthesis through the scrotum in a diabetic patient.
    Ihor S. Sawczuk, Michael E. Wechsler · 1985 · PubMed Central
  17. Cell and gene therapeutic approaches in non-alcoholic fatty liver disease
    Mohadeseh Poudineh, Fatemeh Mohammadyari, Negin Parsamanesh, Tananz Jamialahmadi, Prashant Kesharwani, Amirhossein Sahebkar · 2025 · Gene
  18. Hitting the Target Without Pulling the Trigger
    Thierry VandenDriessche, Marinee Chuah · 2015 · Molecular Therapy
  19. Genetic and Epigenetic Modification of Rat Liver Progenitor Cells via HNF4α Transduction and 5’ Azacytidine Treatment: An Integrated miRNA and mRNA Expression Profile Analysis
    Jennifer Bolleyn, Matthias Rombaut, Nisha Nair, Steven Branson, Anja Heymans, Marinee Chuah, Thierry VandenDriessche, Vera Rogiers, Joery De Kock, Tamara Vanhaecke · 2020 · Genes
  20. Regulatory T Cells in Autoimmune Diabetes
    Vitalijs Ovcinnikovs, Lucy S. K. Walker · 2015 · Progress in molecular biology and translational science
  21. Platelet‐directed gene therapy overcomes inhibitory antibodies to factor VIII
    Marinee Chuah, Thierry VandenDriessche · 2012 · Journal of Thrombosis and Haemostasis
  22. Gene Therapy for Liver Disease
    Rajagopal N. Aravalli · 2017 · Elsevier eBooks
  23. Development of viral & non-viral episomal vectors for gene therapy applications
    Hanna Kymäläinen · 2012 · OpenGrey (Institut de l'Information Scientifique et Technique)
  24. Recent Advances and Future Perspectives in Lentiviral Gene Therapy for Hemophilia A and B
    Janka Mátrai, Marinee Chuah, Thierry VandenDriessche · 2012 · Journal of Genetic Syndromes & Gene Therapy
  25. GENE THERAPY FOR HAEMOPHILIA
    A Asghar, Zarafshan Asjad, H Tahir, Z Maheen, S Hanif · 2021 · Pakistan Journal of Intensive Care Medicine
  26. Molecular and Genetic Medicine
    Thorsten Bergmann, Eric Ehrke‐Schulz, Anja Ehrhardt · 2014
  27. A universal platform for simultaneous TCRα/β removal enables safer and more potent TCR therapies and autoimmune modeling
    Giorgia Zanetti, Mateusz Legut, Austin Chen, Farshid Fathi, Nathan Suek, Nato Teteloshvili, Hao Wei Li, Xiaolan Ding, Daniel Traum, Klaus H. Kaestner et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  28. Assessing the potential of non-integrating lentiviral vectors for cardiovascular gene therapy
    Helen Elizabeth Chick · 2011 · Enlighten: Theses (The University of Glasgow)
  29. Strategies for the Gene Modification of Megakaryopoiesis and Platelets
    Lisette J. Latorre-Rey, Ute Modlich · 2016 · Springer eBooks
  30. MDS1/EVI1 and PRDM16 deregulation in hematopoiesis after experimental and clinical gene transfer
    Wang, Wei · 2012 · heiDOK (Heidelberg University)
  31. Insights into the mechanisms of HIV-1 cis elements and trans factors required for RNA encapsidation and transduction
    Adam S. Cockrell · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  32. Controlling Transgene Expression in the Central Nervous System For MRI-Guided Focused Ultrasound Delivery of Adeno-Associated Virus
    Danielle Weber‐Adrian · 2017 · TSpace (University of Toronto)
  33. A study of mechanisms of genotoxicity in mammalian cells by retrovirus vectors intended for gene therapy
    Safia Reja · 2013 · Brunel University Research Archive (BURA) (Brunel University London)
  34. Faculty Opinions recommendation of Efficient In Vivo Liver-Directed Gene Editing Using CRISPR/Cas9.
    Irina M. Conboy · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  35. Identification of Hepatocyte-Primed Biliary Epithelial Cells in the Homeostatic Liver by in vivo Lentiviral Gene Transfer to Mice and Non-Human Primates
    Michela Milani, Francesco Starinieri, Stefano Beretta, Anna Fabiano, Tiziana Plati, Cesare Canepari, Mauro Biffi, Fabio Russo, Rossana Norata, Francesca Sanvito et al. · 2023 · SSRN Electronic Journal
  36. Cell of origin epigenetic priming determines susceptibility to Tet2 mutation
    Giulia Schiroli, Vinay K. Kartha, Fabiana M. Duarte, Trine Ahn Kristiansen, Christina Mayerhofer, Rojesh Shrestha, Andrew Earl, Yan Hu, Tristan Tay, Catherine Rhee et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  37. LSpECifying transgene expression
    Andrea Annoni, Alessio Cantore · 2024 · Molecular Therapy — Nucleic Acids
  38. In vivo delivery and clinical advances of RNA therapeutics and vaccines
    Tingting Zhao, Shuai Guo, Yuanyu Huang · 2026 · Scientia Sinica Vitae
  39. Stealthy lentiviral vectors: Breaking the barriers to systemic in vivo gene delivery
    Amy L. Keating, Robert C. Carlisle, Kyriacos A. Mitrophanous, L. W. Seymour, Kerry D. Fisher · 2026 · Molecular Therapy Advances