Dendritic Cells Limit Fibroinflammatory Injury in Nonalcoholic Steatohepatitis in Mice

Henning, Justin R., Graffeo, Christopher S., Rehman, Adeel, Fallon, Nina C., Zambirinis, Constantinos P., Ochi, Atsuo, Barilla, Rocky, Jamal, Mohsin +9 more·2013·Hepatology

Cited by (184)

Items 101–184 of 184

  1. Hepatic transcriptome profiling reveals early signatures associated with disease transition from non-alcoholic steatosis to steatohepatitis
    Nancy S. Magee, Forkan Ahamed, Natalie Eppler, Elizabeth Jones, Priyanka Ghosh, Lily He, Yuxia Zhang · 2022 · Liver Research
  2. Liver dendritic cells and NAFLD evolution: A remaining open issue.
    C. Bernsmeier, E. Albano · 2017 · Journal of Hepatology
  3. The Alteration of Immune Cells in the Pathogenesis of non-Alcoholic Fatty Liver Disease and non-Alcoholic Steatohepatitis
    Feng, Dechun · 2020 · Liver Research
  4. State of CD8+ T cells in progression from nonalcoholic steatohepatitis to hepatocellular carcinoma: From pathogenesis to immunotherapy
    Xin Zhong, Minling Lv, Mengqing Ma, Qi Huang, Rui Hu, Jing Li, Jinyu Yi, Jialing Sun, Xiaozhou Zhou · 2023 · Biomedicine & Pharmacotherapy
  5. Theaphenon E prevents fatty liver disease and increases CD4+ T cell survival in mice fed a high-fat diet
    Heidi Coia, Ning Ma, Yanqi Hou, Eva Permaul, Deborah L. Berry, Maria Idalia Cruz, Evan L. Pannkuk, Michael J. Girgis, Zizhao Zhu, Yichen Lee et al. · 2020 · Clinical Nutrition
  6. Myeloid cells in chronic liver inflammation
    Dimitrios Patseas, Ahmed El-Masry, Zuobin Liu, Prakash Ramachandran, Evangelos Triantafyllou · 2025 · Cellular and Molecular Immunology
  7. Choline Deficiency Causes Colonic Type II Natural Killer T (NKT) Cell Loss and Alleviates Murine Colitis under Type I NKT Cell Deficiency
    Shintaro Sagami, Yoshitaka Ueno, Shinji Tanaka, Akira Fujita, Hiroaki Niitsu, Ryohei Hayashi, Hideyuki Hyogo, Takao Hinoi, Yasuhiko Kitadai, Kazuaki Chayama · 2017 · PLoS ONE
  8. Gut microbiome-derived glycine lipids are diet-dependent modulators of hepatic injury and atherosclerosis
    Courtney L. Millar, Liya Anto, Chelsea Garcia, Mi‐Bo Kim, Anisha Jain, Anthony A. Provatas, Robert Brown Clark, Ji‐Young Lee, Frank C. Nichols, Christopher N. Blesso · 2022 · Journal of Lipid Research
  9. Liver DCs in health and disease
    Theresa Hildegard Wirtz, Elisa Fabiana Brandt, Marie‐Luise Berres · 2019 · International review of cytology
  10. Unmet needs in pediatric NAFLD research: what do we need to prioritize for the future?
    Grace B. Hatton, Tommaso Alterio, Valério Nobili, Jake Peter Mann · 2018 · Expert Review of Gastroenterology & Hepatology
  11. Chinese herbal formula in the treatment of metabolic dysfunction-associated steatotic liver disease: current evidence and practice
    Shao-Hong Tao, Y. Lei, Yi Tan, Yu-bo Yang, Wei Xie · 2024 · Frontiers in Medicine
  12. The many pathways driving liver inflammation in MASH
    Herbert Tilg, Timon Erik Adolph, Stefano Romeo, Rohit Seth Loomba · 2026 · Cell Metabolism
  13. CX3CR1 modulates the anti-inflammatory activity of hepatic dendritic cells in response to acute liver injury
    Salvatore Sutti, Felix Heymann, Stefania Bruzzì, Julia Peusquens, Christian Trautwein, Emanuele Albano, Frank Tacke · 2017 · Clinical Science
  14. The double roles of T cell-mediated immune response in the progression of MASLD
    Zigan Li, Shujun Wang, Qinchen Xu, Xin Su, Yunshan Wang, Lina Wang, Yong Zhang · 2024 · Biomedicine & Pharmacotherapy
  15. Hepatocellular carcinoma in nonalcoholic fatty liver disease: A growing challenge
    Â. Mattos, J. Debes, R. Dhanasekaran, J. Benhammou, M. Arrese, André Luiz V. Patrício, A. C. Zilio, Angelo A. Mattos · 2021 · World Journal of Hepatology
  16. Is there a role for adaptive immunity in nonalcoholic steatohepatitis?
    S. Sutti, A. Jindal, S. Bruzzì, Irene Locatelli, C. Bozzola, E. Albano · 2015 · World Journal of Hepatology
  17. Innate and Adaptive Immunity Alterations in Metabolic Associated Fatty Liver Disease and Its Implication in COVID-19 Severity
    Patricia Lamadrid, M. Alonso-Peña, David San Segundo, M. Arias-Loste, J. Crespo, M. López-Hoyos · 2021 · Frontiers in Immunology
  18. Immunotherapy resistance in MASLD-related hepatocellular carcinoma: special immune microenvironment and gut microbiota
    Jie Jin, Kun Cheng, Ming-Rui Chen, Huifang Liang, Wan-Guang Zhang · 2025 · International Journal on Biological Sciences
  19. A high-trans fat, high-carbohydrate, high-cholesterol, high-cholate diet-induced nonalcoholic steatohepatitis mouse model and its hepatic immune response
    Qian Zhang, Yue Jin, Xin Xin, Ziming An, Yiyang Hu, Yajuan Li, Qin Feng · 2023 · Nutrition & Metabolism
  20. Immune-related pathogenesis and therapeutic strategies of nonalcoholic steatohepatitis
    Ki Wung Chung, Ye Eun Cho, Seung-Jin Kim, Seonghwan Hwang · 2022 · Archives of Pharmacal Research
  21. Alteration in immune function in patients with fatty liver disease
    Stephanie N. Gregory, Shruthi Reddy Perati, Zachary J. Brown · 2022 · Hepatoma Research
  22. Activation of cDCs and iNKT cells contributes to triptolide-induced hepatotoxicity via STING signaling pathway and endoplasmic reticulum stress
    Xin Chen, Zixun Yu, Cheng Nong, Rufeng Xue, Mingxuan Zhang, Yiying Zhang, Lixin Sun, Luyong Zhang, Xinzhi Wang · 2022 · Cell Biology and Toxicology
  23. Screening of Biomarkers in Liver Tissue after Bariatric Surgery Based on WGCNA and SVM-RFE Algorithms
    Yi-Cheng Jiang, Yu Wang, Shuai Chen, Zhixin Liu, Hao-Jun Yang, Yuwen Jiao, Li-Ming Tang · 2023 · Disease Markers
  24. Identification of Hepatic Dendritic Cells in Liver Biopsies Showing Steatosis in Patients with Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Associated with Obesity
    Beatriz Barranco-Fragoso, Shreya C. Pal, Luis E. Díaz-Orozco, Rita Dorantes-Heredia, Xingshun Qi, Nahúm Méndez‐Sánchez · 2022 · Medical Science Monitor
  25. Maintaining T cell tolerance of alloantigens: Lessons from animal studies
    Kortney A. Robinson, William Orent, Joren C. Madsen, Gilles Bénichou · 2018 · American Journal of Transplantation
  26. The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis
    Cordula Hansel, S. Erschfeld, Maike Baues, T. Lammers, R. Weiskirchen, C. Trautwein, D. Kroy, Hannah K. Drescher · 2019 · Frontiers in Pharmacology
  27. Role of Innate Immunity in Pediatric Post-transplant Idiopathic Liver Fibrosis
    Yue Hui Wu, Mingzhu Huang, Haojie Sun, Xiying Zhou, Ruoqiao Zhou, Guangxiang Gu, Qiang Xia · 2020 · Frontiers in Immunology
  28. Oxidative stress in nonalcoholic fatty liver disease: a reappraisal of the role in supporting inflammatory mechanisms
    Salvatore Sutti, Emanuele Albano · 2022 · Redox Experimental Medicine
  29. Celastrol Stabilizes Glycolipid Metabolism in Hepatic Steatosis by Binding and Regulating the Peroxisome Proliferator-Activated Receptor γ Signaling Pathway
    Mingzhu Luo, Yiting Wang, Yanyan Ma, Jingzhe Li, Jingyi Wang, Changzhen Liu · 2024 · Metabolites
  30. The role of dendritic cells in MASH: friends or foes?
    Antonio Pinto, Veronika Lukacs-Kornek · 2024 · Frontiers in Immunology
  31. An improved method for isolation and flow cytometric characterization of intrahepatic leukocytes from fatty and fibrotic liver tissues
    R. Kandhi, Bhavesh C. Variya, S. Ramanathan, S. Ilangumaran · 2022 · The Anatomical Record
  32. Methionine- and Choline-Deficient Diet Identifies an Essential Role for DNA Methylation in Plasmacytoid Dendritic Cell Biology
    Bhupendra Singh Rawat, Ramya Venkataraman, Roli Budhwar, Prafullakumar B. Tailor · 2022 · The Journal of Immunology
  33. LPS pretreatment ameliorates D-galactosamine/lipopolysaccharide-induced acute liver failure in rat.
    Jin‐Zhong Dong, Li-Ping Wang, Sainan Zhang, Keqing Shi, Shaolong Chen, Naibin Yang, Shunlan Ni, Jian‐Hua Zhu, Mingqin Lu · 2014 · Europe PMC (PubMed Central)
  34. Dendritic cells in NASH: Friend or foe?
    Priya Handa, Kris V. Kowdley · 2013 · Annals of Hepatology
  35. Myeloid Cells and Chronic Liver Disease: a Comprehensive Review
    Min Lian, Carlo Francesco Selmi, Merrill Eric Gershwin, Xiong Ma · 2018 · Clinical Reviews in Allergy & Immunology
  36. The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease
    Camilla Klaimi, Wan Ting Kong, Camille Blériot, Joel T. Haas · 2024 · FEBS Letters
  37. Identification of Key Biomarkers and Immune Infiltration in Liver Tissue after Bariatric Surgery
    Xiaoyan Zhang, Jingxin Li, Tiancai Liu, Min Zhao, Baozhu Liang, Hong Chen, Zhen Zhang · 2022 · Disease Markers · Retracted
  38. Use of a ferroptosis-related gene signature to construct diagnostic and prognostic models for assessing immune infiltration in metabolic dysfunction-associated fatty liver disease
    Xin Lian, Xulei Tang · 2023 · Frontiers in Cell and Developmental Biology
  39. Causal relationship between key genes and metabolic dysfunction‐associated fatty liver disease risk mediated by immune cells: A Mendelian randomization and mediation analysis
    Gong Feng, Na He, Jing Gao, Xiao‐Cheng Li, Fenna Zhang, Chengcheng Liu, Giovanni Targher, Christopher D. Byrne, Man Tian Mi, Ming‐Hua Zheng et al. · 2024 · Diabetes Obesity and Metabolism
  40. Immunology and treatments of fatty liver disease
    Sainan Tang, Shanshan Wu, Wenzhe Zhang, Lili Ma, Li Zuo, Hua Wang · 2024 · Archives of Toxicology
  41. Ablation of histone methyltransferase Suv39h2 in hepatocytes attenuates NASH in mice
    Shiqiang Wu, Wenjing Ren, Jiameng Hong, Yuyu Yang, Yunjie Lu · 2024 · Life Sciences
  42. Stimulation of regulatory dendritic cells suppresses cytotoxic T cell function and alleviates DEN-induced liver injury, fibrosis and hepatocellular carcinoma
    Junjie Wang, Pixu Gong, Qingqing Liu, Menglei Wang, Dengfang Wu, Mengyu Li, Shujie Zheng, Han Wang, Qiaoming Long · 2025 · Frontiers in Immunology
  43. The immunometabolic nature of MASH: framing immune cells within metabolic dysfunction
    Sergio González-Serrano, Alina-Iuliana Onoiu, Andrea Jiménez-Franco, Vicente Cambra-Cortés, Jordi Camps, Jorge Joven · 2026 · Frontiers in Immunology
  44. Non-alcoholic fatty liver disease and intestinal immune status: a narrative review
    Hao Wu, Yalan Lei, Jingwei Mao · 2022 · Scandinavian Journal of Gastroenterology
  45. Immune and Inflammatory Pathways in Non-Alcoholic Steatohepatitis (NASH). An update
    Sorina Cezara Coste, Ionela Popovici, Andreea Stefan, Iulia Breaban, Adela Viviana Sitar Tǎut, Simina Țărmure, Angela Cozma, Dorel Sâmpelean, Olga Hilda Orasan, Vasile Negrean et al. · 2019 · Journal of Mind and Medical Sciences
  46. Mechanisms of Fibrosis in Steatohepatitis
    Fabio Marra, Angela Provenzano, Elisa Vivoli · 2014 · Current Hepatology Reports
  47. Hepatic Stellate Cells as Target for Reversal of Fibrosis/Cirrhosis
    Sophie Lotersztajn, Ariane Mallat · 2015 · Elsevier eBooks
  48. Nonalcoholic Steatohepatitis Exacerbates Inflammatory Bone Destruction and Macrophage NLR Family Pyrin Domain-Containing 3 Inflammasome Activation in Ligature-Induced Periodontitis
    Zijun Wang, Xiaoyue Sun, ZhaoJun Chen, Jingjing Yu, Qing Nie, Zihan Ma, Shuhui Zhou, Ting Li, Hantao Yao, Boxuan Zhao et al. · 2025 · American Journal Of Pathology
  49. [Non alcoholic-fatty liver disease causes selective CD4+ T lymphocytes loss and promotes hepatocarcinogenesis].
    Antoine L’Hermitte, S. Pham, Mathilde Cadoux, J. Couty · 2016 · Medecine sciences : M/S
  50. Progress in the study on innate immunity and non-alcohol fatty liver disease.
    Jingfeng Lou, Guangyu Yan, Zhijun Huang, Hong Yuan, Yao Lu · 2020 · PubMed
  51. NingXueShengBan Decoction Regulates Immune Homeostasis by PI3 K/Akt/mTOR and TLR4/NF-κB Signaling Pathways in Immune Thrombocytopenia Patients
    Haijin Wang, Mengxiao Wang, Wuxia Yang, Runfeng Ni, Lin Ma, Dan Wang, Chao Yan, Yuhong Wu, Baoshan Liu, Aidi Wang · 2024 · Natural Product Communications
  52. Identification of pyroptosis-associated gene to predict fibrosis and reveal immune characterization in non-alcoholic fatty liver disease
    Sha Tu, Jing Xi, Xiaoling Bu, Q Zhang, Shanying Liao, Xiaobo Zhu, Ying Guo, Weihong Sha · 2025 · Scientific Reports
  53. Potential mechanisms of natural metabolites and botanical drugs foumulae for the treatment of non-alcoholic fatty liver disease: targeting the gut microbiota to modulate the immune system
    Yutian Zhang, Lang Liu, Ruihao Song, Ziyi Qu, Tianlin Wang, Lei Liang, Shunhua Wang, Shuzhi Zhang, Huizhen Li, Hong Wang · 2025 · Frontiers in Pharmacology
  54. Role of Dendritic Cells in Mediating the Effect of Growth Differentiation Factor 15 on Nonalcoholic Fatty Liver Disease: Insights From Causal Inference and Single‐Cell Profiling
    Tao Yao, Peng Zheng, Zhe-Ning Wang, Luo-Xiang Fang, Yaoxin Wu, Yuan-Nan Lin · 2025 · Mediators of Inflammation
  55. Clinical and Experimental Immune Tolerance in Pediatric Liver Transplantation
    Ahmed Mohammed Elsabbagh, Yannis Hadjiyannis, Julien Vionnet, Angus W. Thomson · 2026 · Pediatric Transplantation
  56. Role of ubiquitin regulatory X domain‑containing protein 3B in the development of hepatocellular carcinoma (Review)
    Ziwei Guo, Jun Liang · 2023 · Oncology Reports
  57. Identification of m6A-associated autophagy genes in non-alcoholic fatty liver
    Ziqing Huang, Linfei Luo, Zhengqiang Wu, Xiao Zhihua, Zhili Wen · 2024 · PeerJ
  58. Immunotherapy and MASLD-Related HCC: Should We Reconsider the Role of Etiology in the Therapeutic Approach to HCC?
    Giuseppina Vizioli, Alberto Nicoletti, Feliciani Daniela, Barbara Funaro, Lorenzo Zileri Dal Verme, Francesca Romana Ponziani, Maria Assunta Zocco, Antonio Gasbarrini, Maurizio Gabrielli · 2025 · Applied Sciences
  59. SOCS8 deficiency models MAFLD-like progression in the zebrafish gut‒liver axis
    Qingsong Zhu, Hong Yang, Fatima Altaf, Nan Wu, Yuhang Hu, Lian Feng Su, Jialin Li, Junheng Liu, Guangxin Wang, Deinyefa Godfree Igbiriki et al. · 2025 · Water Biology and Security
  60. New Paradigms in the Histopathology of NAFLD
    Andrew Donald Clouston, Victoria L. Gadd, Katharine M. Irvine, Elizabeth Ellen Powell · 2014 · Current Hepatology Reports
  61. Emerging Roles for Lipids in the Hepatic Innate Immune
    Michael Kremer, Edward J. Sanderlin, Ian Neil Hines · 2013
  62. Immunological and molecular mechanisms in NAFLD
    Ionel Copaci, Laurenţiu Micu, Grethi Chiriac, Eugenia Mindrut, Gener Ismail, Luminiţa Leurzeanu · 2015 · Journal of Translational Medicine and Research
  63. Innate immune response and non-alcoholic fatty liver disease
    Meihua Li, Xiao Xinhua · 2016
  64. Lipid metabolism and inflammation in the pathogenesis of chronic liver diseases
    Sowmya Narayanan · 2016
  65. Dendritic Cells and T Cell Subsets in the Development of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis
    Maya Vladova Gulubova, Mehmed Hadzhi, L. Hadzhilieva, Dimitur Chavdarov Chonov, M. Ignatova · 2021 · Acta Medica Bulgarica
  66. Hepatology Highlights
    Nancy Edith Aguilar-Olivos, Nahúm Méndez‐Sánchez · 2014 · Annals of Hepatology
  67. The Role of Myeloid-Derived Cells in the Progression of Liver Disease
    2020 · Frontiers research topics
  68. Angeborene und erworbene Immunität im Kontext der nichtalkoholischen Fettlebererkrankung
    Bernd Heinrich · 2022 · Zeitschrift für Gastroenterologie - German Journal of Gastroenterology
  69. Sinusoidal cells and liver immunology
    Karolina Szafranska, Karen Kristine Sørensen, Patricia F. Lalor, Peter McCourt · 2024 · Elsevier eBooks
  70. Role of triggering receptor expressed on myeloid cells 2 in the pathogenesis of non-alcoholic fatty liver disease
    Lihui Zhang, Sutong Liu, Qing Zhao, Xiao-Yan Liu, Tong Liu, Qiang Zhang, Ming-Hao Liu, Wenxia Zhao · 2025 · World Journal of Hepatology
  71. Low Hepatic CEACAM1 Tethers Metabolic Dysfunction Steatohepatitis to Atherosclerosis
    Sacha El Khoury, Sami N. Al Harake, Tya Youssef, Carl E. Risk, Naim G. Helou, Natalie M. Doumet, K. Aramouni, Sami Azar, Sonia M. Najjar, Hilda E. Ghadieh · 2025 · Livers
  72. Non-alcoholic steatohepatitis
    Miguel M. Pinheiro, Marta B. Afonso, Cecília M. P. Rodrigues · 2025 · Elsevier eBooks
  73. L’autophagie macrophagique protège contre l'atteinte hépatique et la fibrose au cours de la maladie alcoolique du foie
    Jasper Lodder · 2014 · theses.fr (ABES)
  74. Roles of hepatic immunity in metabolic dysfunction-associated steatotic liver disease: Cellular and molecular mechanisms and clinical trials
    Ming Yang, Olamide Tosin Olaoba, Stephanie Chinwo, Hannah Lauren LeVasseur, Beiyan Zhou, Eric T. Kimchi, Kevin F. Staveley-O’Carroll, Guangfu Li · 2026 · World Journal of Gastroenterology
  75. Rôle du récepteur purinergique P2X4 dans l'activation des myofibroblastes au cours de la fibrogenèse hépatique
    Camille Le Guilcher · 2018 · theses.fr (ABES)
  76. Role of RIPK1 in the survival and death of hepatocytes : its involvement in murine hepatitis models
    Muhammad Farooq · 2019 · theses.fr (ABES)
  77. Contribution des cellules innées lymphoïdes de groupe 1 dans le développement de la stéatohépathie non alcoolique du foie
    Élodie Vieira · 2020 · theses.fr (ABES)
  78. Influence of bile acids metabolism on hepatic immunity in mice
    Valentine Guinot · 2022 · theses.fr (ABES)
  79. Rôle de REG3A dans la maladie métabolique du foie d'origine nutritionnelle
    Tung-Son Nguyen · 2024 · theses.fr (ABES)
  80. Caractérisation de la fibrose dans l'hépatite alcoolique et décryptage des mécanismes liant cette fibrose au défaut du compartiment hépatocytaire
    Line Carolle Ntandja Wandji · 2024
  81. Dynamic immune landscape of NAFLD highlights pDCs as predictive biomarkers for disease progression
    Guozhen Huang, Siyi Xing, Zhaojun Long, Wei Gao, Shaolei Kuang, Mingjiang Liu, Yan Zou, Chenyi Zhuo, Xiaofeng Dong · 2026 · Frontiers in Immunology
  82. Exploring the potential role of ADIPOR2 related to immune microenvironment and metabolism dysfunction in non-alcoholic steatohepatitis
    Lei Lei, Xinyu Huang, Yun Hu, Wanying Yu, Die Zhang · 2026 · Medicine
  83. Hepatocyte-Specific Deficiency of Endoplasmic Reticulum-Associated Degradation Induces Coordinated Innate–Adaptive Immune Responses
    Qingqing Liu, Junjie Wang, Haiying Zong, Hongqiong Ma, Mengyu Li, Menglei Wang, Dengfang Wu, Shujie Zheng, Han Wang, Qiaoming Long · 2026 · Cells
  84. Metabolic Dysfunction-Associated Steatohepatitis: Is There Evidence for Fractured CD4+ T-Cell Tolerance in the Immunopathogenesis
    Abigail E. Russi, Brian J. DeBosch · 2026 · Cellular and Molecular Gastroenterology and Hepatology