MicroRNA-26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting interleukin-6-Stat3 pathway

Yang, Xin, Liang, Lei, Zhang, Xiao-Fei, Jia, Hu-Liang, Qin, Yi, Zhu, Xu-Chao, Gao, Xiao-Mei, Qiao, Peng, Zheng, Yan, Sheng, Yuan-Yuan, Wei, Jin-Wang, Zhou, Hai-Jun, Ren, Ning, Ye, Qing-Hai, Dong, Qiong-Zhu, Qin, Lun-Xiu·2013·Hepatology

Cited by (280)

Items 201–280 of 280

  1. Simultaneous detection of two hepatocellar carcinoma-related microRNAs using a clever single-labeled fluorescent probe
    Rong Liao, Shiyu Li, Huan Wang, Chunyan Chen, Xiaoming Chen, Changqun Cai · 2017 · Analytica Chimica Acta
  2. MiR-520f promotes cell aggressiveness by regulating fibroblast growth factor 16 in hepatocellular carcinoma
    Feng Xu, Wen Feng Xie, Guo Qing Zha, Hong Wu Chen, Liang Deng · 2017 · Oncotarget · Retracted
  3. GATA3 suppresses human fibroblasts-induced metastasis of clear cell renal cell carcinoma via an anti-IL6/STAT3 mechanism
    Qianqian Shi, Renfang Xu, Guanglai Song, Lu Hao, Dong Xue, Xiaozhou He, Ying Xia · 2019 · Cancer Gene Therapy
  4. CCN3 is a therapeutic target relating enhanced stemness and coagulation in hepatocellular carcinoma
    Qingan Jia, Tong‐Chun Xue, Qiangbo Zhang, Wei Cheng, Chun Zhang, Jingwei Ma, Yang Bu, Songning Yu, Qingguang Liu · 2017 · Scientific Reports
  5. MiR-302a-5p suppresses cell proliferation and invasion in non-small cell lung carcinoma by targeting ITGA6.
    Wei Chen, Xibing Zhuang, Ruixue Qi, Tiankui Qiao · 2019 · PubMed Central
  6. A miRNA-mediated attenuation of hepatocarcinogenesis in both hepatocytes and Kupffer cells
    Yan Tian, Mingfeng Zhang, Mingjie Fan, Haixia Xu, Shun‐Quan Wu, Sailan Zou, Yangmeng Wang, Dongmei Tang, Chunyan Zhang, Weidong Han et al. · 2022 · Molecular Therapy — Nucleic Acids
  7. LncSOX4 serves an oncogenic role in the tumorigenesis of epithelial ovarian cancer by promoting cell proliferation and inhibiting apoptosis
    Yulan Liu, Yan Wang, Dongmei Yao, Diansheng Cui · 2018 · Molecular Medicine Reports
  8. Knockdown of miR-299-5p inhibits the progression of hepatocellular carcinoma by targeting SIAH1
    Xinghua Jiang, Xiaoxu Shen · 2018 · Bulletin du Cancer
  9. circBGN accelerates gastric cancer cell proliferation and invasion via activating IL6/STAT3 signaling pathway
    Chenghui Li, Xiang Peng, Zhiyong Peng, Bin Yan · 2022 · The FASEB Journal
  10. Actein ameliorates hepatobiliary cancer through stemness and p53 signaling regulation
    Rui Xi, Li-Juan Wang · 2017 · Biomedicine & Pharmacotherapy
  11. MicroRNA-425 promotes the development of lung adenocarcinoma via targeting A disintegrin and metalloproteinases 9 (ADAM9)
    Ruibao Liu, Fang Wang, Yanchun Guo, Jianmei Yang, Shaoping Chen, Xin Gao, Xunguo Wang · 2018 · OncoTargets and Therapy
  12. MicroRNA profiles in cisplatin-induced apoptosis of hepatocellular carcinoma cells
    MIWA MIYATA, Asahiro Morishita, Teppei Sakamoto, Akiko Katsura, Kiyohito Kato, Tomoko Nishioka, Yuka Toyota, Koji Fujita, Emiko Maeda, Takako Nomura et al. · 2015 · International Journal of Oncology
  13. Natural killer cells inhibit pulmonary metastasis of hepatocellular carcinoma in nude mice
    Zaifa Hong, Wenxiu Zhao, Zhenyu Yin, Chengrong Xie, YA-PING XU, Xiaoqin Chi, SHENG ZHANG, Xiaomin Wang · 2016 · Oncology Letters
  14. Mesoporous Core–Cone Silica Nanoparticles Can Deliver miRNA-26a to Macrophages to Exert Immunomodulatory Effects on Osteogenesis In Vitro
    Sepanta Hosseinpour, Huan Dai, Laurence James Walsh, Chun Xu · 2023 · Nanomaterials
  15. GPM6A expression is suppressed in hepatocellular carcinoma through miRNA-96 production
    Zong-Rui Li, Gang Xu, Liuyan Zhu, Hui Chen, Ji‐Min Zhu, Jian Wu · 2022 · Laboratory Investigation
  16. Noncoding RNAs Regulating p53 and c-Myc Signaling
    Yide Mei, Mian Wu · 2016 · Advances in experimental medicine and biology
  17. Role of microRNAs in the development of hepatocellular carcinoma and drug resistance
    Deepak Kumar · 2018 · Frontiers in bioscience
  18. MicroRNA 26a prolongs skin allograft survival and promotes regulatory T cell expansion in mice
    Feng Xie, Jiake Chai, Zhengwen Zhang, Quan Hu, Tengxiao Ma · 2015 · Transplant International
  19. Role of MicroRNAs in the Development of Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease
    Cheng Zhang, Ping Wang, Yongqiang Li, Changxin Huang, Wei Min NI, Yidan Chen, Junping Shi, Gongying Chen, Xiangrong Hu, Meng Ye et al. · 2018 · The Anatomical Record
  20. Association between microRNA‑527 and glypican‑3 in hepatocellular carcinoma
    Kei Nomura, Akira Kitanaka, Hisakazu Iwama, Joji Tani, Takako Nomura, M. Nakahara, Kyoko Oura, Tomoko Tadokoro, Koji Fujita, Shima Mimura et al. · 2021 · Oncology Letters
  21. Hsa-miR-323a-3p functions as a tumor suppressor and targets STAT3 in neuroblastoma cells
    Swapnil Parashram Bhavsar, Lotte Olsen, Cecilie Løkke, Jan Köster, Trond Flægstad, Christer Einvik · 2023 · Frontiers in Pediatrics
  22. Molecular epigenetic targets for liver diseases: current challenges and future prospects
    Robert B. Zeidler, Bruno Freitas, Augustinus Bader, Shibashish Giri · 2017 · Drug Discovery Today
  23. Reduction sensitive CC9-PEG-SSBPEI/miR-148b nanoparticles: Synthesis, characterization, targeting delivery and application for anti-metastasis
    Cui Cheng, Zhihong Zhang, Siyuan Wang, Lixia Chen, Qinying Liu · 2019 · Colloids and Surfaces B Biointerfaces
  24. Host defense peptide LL-37 is involved in the regulation of cell proliferation and production of pro-inflammatory cytokines in hepatocellular carcinoma cells
    Xiaohui Ding, Dongyan Bian, Weike Li, Yafeng Xie, Xiangyang Li, Jilong Lv, Renxian Tang · 2021 · Amino Acids
  25. Unique microRNA expression in the colonic mucosa during chronic HIV-1 infection
    Jennifer A. Fulcher, Γεώργιος Κούκος, Μαρίνα Κουτσιούμπα, Julie E. Elliott, Alexandra Drakaki, Dimitrios Iliopoulos, Peter A. Anton · 2017 · AIDS
  26. Long Noncoding RNA RMRP Suppresses the Tumorigenesis of Hepatocellular Carcinoma Through Targeting microRNA-766
    Cunhua Shao, Gongpan Liu, Xiaobin Zhang, Anyun Li, Xingjun Guo · 2020 · OncoTargets and Therapy
  27. A review on the lncRNA-miRNA-mRNA regulatory networks involved in inflammatory processes in Alzheimer’s disease
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  28. The variant of pri-mir-26a-1 polymorphism is associated with decreased risk of betel quid–related oral premalignant lesions and oral squamous cell carcinoma
    Cheng‐Mei Yang, Chien‐Chou Chen, Yu‐Kai Tseng, Sin-Jhih Huang, Huei‐Han Liou, Yi-Cheng Lee, Jang-Hwa Lee, Jyh‐Seng Wang, Hung-Chih Chen, Chao‐Chuan Chi et al. · 2017 · Oral Surgery Oral Medicine Oral Pathology and Oral Radiology
  29. Effects of Connexin 32-Mediated Lung Inflammation Resolution During Liver Ischemia Reperfusion
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  30. Correction: GATA3 suppresses human fibroblasts-induced metastasis of clear cell renal cell carcinoma via an anti-IL6/STAT3 mechanism
    Qianqian Shi, Renfang Xu, Guanglai Song, Lu Hao, Dong Xue, Xiaozhou He, Ying Xia · 2020 · Cancer Gene Therapy
  31. Involvement of Small Non-Coding RNA and Cell Antigens in Pathogenesis of Extramedullary Multiple Myeloma
    Monika Vlachová, Jana Gregorová, Petra Vychytilová-Faltejsková, Natalia Gabło, Lenka Radová, Lenka Pospíšilová, Martina Almáši, Martin Štork, Zdeňka Knechtová, Jiří Minařík et al. · 2022 · International Journal of Molecular Sciences
  32. MicroRNA as Key Players in Hepatocellular Carcinoma: Insights into Their Role in Metastasis
    Mohamed Jamal Saadh, Qusay Mohammed Hussain, Tuqa S. Alazzawi, Ali A. Fahdil, Zainab H. Athab, Bekhzod Yarmukhamedov, Ali M. Ali Al-Nuaimi, Fahad Alsaikhan, Bagher Farhood · 2024 · Biochemical Genetics
  33. A facile combined therapy of chemotherapeutic agent and microRNA for hepatocellular carcinoma using non-cationic nanogel
    Dingyue Zhang, Mingxiang Zuo, Jinhui Zhou, Siyu Ouyang, Shuang Liu, Jianming Yuan, Chiyi Ou, Qinghua Chen, Dongsheng Yu, Du Cheng et al. · 2025 · Journal of Materials Chemistry B
  34. microRNA and Other Small RNA Sequence Profiling across Six Tissues of Chinese Forest Musk Deer ( Moschus berezovskii )
    Hang Jie, Pu Zhang, Zhongxian Xu, Shailendra Kumar Mishra, Meiyan Lei, Dejun Zeng, Guijun Zhao, Diyan Li · 2019 · BioMed Research International
  35. The Tumorigenic Properties of EZH2 are Mediated by MiR-26a in Uveal Melanoma
    Yao Li, Mingmei Zhang, Huayin Feng, Shaya Mahati · 2021 · Frontiers in Molecular Biosciences
  36. Emerging role of MicroRNA-Based theranostics in Hepatocellular Carcinoma
    Abdulhakim Umar Toro, Abdulaziz Umar Kurya, Sudheesh Kumar Shukla, Parveen Bansal · 2023 · Molecular Biology Reports
  37. AP2-microRNA-26a overexpression reduces visceral fat mass and blood lipids
    Hailuan Zeng, Weihong Sun, Xinping Ren, Nan L. Xia, Sheng Zheng, Haixia Xu, Yan Tian, Xianghui Fu, Jingyan Tian · 2021 · Molecular and Cellular Endocrinology
  38. IL-6 Promotes Hepatocellular Carcinoma Invasion by Releasing Exosomal miR-133a-3p
    Xudong Ren, Yu Zhou, Yunling Luo, Chaoqun Wang, Anna Pan, Yanqin Ju, Haoting Sun, Zhifei Lin, Beiyuan Hu, Guangzheng Sun et al. · 2022 · Gastroenterology Research and Practice
  39. BRD4 expression and its regulatory interaction with miR-26a-3p, DLG5-AS1, and JMJD1C-AS1 lncRNAs in gastric cancer progression
    Mahya Ahmadpour Youshanlui, AmirHossein Yari, Seyedeh Zahra Bahojb Mahdavi, Mohammad Amini, Behzad Baradaran, Ramin Ahangar, Omid Pourbagherian, Amir Ali Mokhtarzadeh · 2024 · Discover Oncology
  40. MetastamiRs: A promising choice for antihepatocellular carcinoma nucleic acid drug development
    Liangcai Wu, Xue Bai, Yuan Xie, Zhen Fan Yang, Xiaobo Yang, Jianzhen Lin, Chengpei Zhu, Anqiang Wang, Haohai Zhang, Ruoyu Miao et al. · 2016 · Hepatology Research
  41. A comprehensive review on RNA interference-mediated targeting of interleukins and its potential therapeutic implications in colon cancer
    Sagari Sil, Janet Bertilla, S. Rupachandra · 2022 · 3 Biotech
  42. Decoding hepatocellular carcinoma: the promise of microRNAs.
    Fyza Y. Shaikh, Laura Williams Goff · 2014 · Europe PMC (PubMed Central)
  43. During HCV DAA Therapy Plasma Mip1B, IP10, and miRNA Profile Are Distinctly Associated with Subsequent Diagnosis of Hepatocellular Carcinoma: A Pilot Study
    Sofi Damjanovska, Hawwa Alao, Elizabeth Zebrowski, Corinne M. Kowal, Lenche Kostadinova, Perica Davitkov, Yngve T Falck-Ytter, Carey L. Shive, Michael J. Cartwright, Brian Richardson et al. · 2022 · Biology
  44. Effect of siRNA on Wisp-1 gene expression, proliferation, migration and adhesion of mouse hepatocellular carcinoma cells
    Jian Ge, Xiaohua Zhang, Fang Wang, Yu Wang, Qingyan Li, Tao Wei, Guohua Ren · 2015 · Asian Pacific Journal of Tropical Medicine
  45. In�vitro analysis of microRNA-26a in chronic lymphocytic leukemia cells
    Jing Li, Chang‐Kui Sun · 2018 · International Journal of Molecular Medicine
  46. Exosomal microRNA profiling reveals candidate biomarkers and regulatory signatures associated with paratuberculosis disease status in goats
    Eun‐Yeong Bok, Tae Yoon Kim, Sang-Young Seo, Han-Gyu Lee, Young-Hun Jung, Seong Hwan Bae, Nam Su Oh, Tae Jin Cho, Hyeon Woo Park, Eui Cheol Shin et al. · 2026 · The Veterinary Journal
  47. [MicroRNA-26a and Tumor].
    Qianqian Song, Ke Xu · 2017 · Europe PMC (PubMed Central)
  48. Targeting phase separation: a promising treatment option for hepatocellular carcinoma
    Ziling Zhou, Sikan Jin, Xiaoming Li, Dan Zhang, Shengxi Zhang, He Zhou, Cai Ji, Tao Song, Xianyao Wang, Qinghong Kong et al. · 2025 · Cell Communication and Signaling
  49. Mechanisms of Invasion and Metastasis: Cell Migration and Chemotaxis
    Arthur Zimmermann · 2016 · Springer eBooks
  50. MicroRNAs in Liver Regeneration
    Dakai Yang, Selina Möbus, Asha Balakrishnan, Amar Deep Sharma · 2014 · Elsevier eBooks
  51. Cancer Genetics at a Glance: The Comprehensive Insights
    Asaad Azarnezhad, Parvin Mehdipour · 2017 · Springer eBooks
  52. Chronic Lymphocytic Leukemia (CLL): evaluation of AKT protein kinase and microRNA gene expression related to disease pathogenesis
    Lorena Caixeta Gomes, Rodrigo R. Resende, Ricardo Cambraia Parreira, Cláudia Natália Ferreira, Edna Afonso Reis, Rita Carolina Figueiredo Duarte, Luan Carlos Vieira Alves, Sérgio Schusterschitz da Silva Araújo, María das Graças Carvalho Ferriani, Adriano de Paula Sabino · 2022 · Brazilian Journal of Pharmaceutical Sciences
  53. Integrative transcriptomic analysis reveals miR-26a-5p downregulation and a potential predictive gene signature for the progression of metabolic liver disease
    Andrei Sorop, Alina-Veronica Ghionescu, Diana-Larisa Ancuța, Maria-Gabriela Croitoru, Cristin Coman, Daniela Lixandru, Simona Dima · 2026 · Frontiers in Cell and Developmental Biology
  54. Mechanisms of Invasion and Metastasis: Cell Migration and Chemotaxis
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  55. Multidimensional regulatory networks of noncoding RNAs and hepatocellular carcinoma
    Jine Yang, Chen Xie, LanQi LI, Yu WANG, Ying ZHU, ShiMei ZHUANG · 2023 · Scientia Sinica Vitae
  56. MiR-182 promotes apoptosis of neural cells in cerebral infarction rats by PI3K/AKT signaling pathway
    Yang Ren, Chen Zeng · 2023 · Cellular and Molecular Biology
  57. Revolutionizing HCV Therapy: microRNA Approaches in New Era of Treatment
    Maryam Shafaati, Mohammadreza Salehi, Maryam Zare · 2024 · IntechOpen eBooks
  58. MicroRNA MTCO3P38 Inhibits the TMOD1/MMP13 Pathway to Alleviate the Progression of Hepatocellular Carcinoma
    Ping Wu, Guoyuan Li, Deliang Guo, Tao Guo, Chengwei Chai · 2024 · Journal of Cancer
  59. MicroRNA signatures as predictive biomarkers in transarterial chemoembolization‐treated hepatocellular carcinoma
    Manal Said Fawzy, Eman Ali Toraih · 2021 · Precision Medical Sciences
  60. rAAV-mediated Multi-miRNA Delivery Targeting MAPK Pathway Suppresses Laser-induced Choroidal Neovascularization in Mice
    Han, Jung Woo, Yang, Jin Young, Kim, Yeji, An, Sumin, Yoo, Eunjae, Park, In Hwan, Lee, Sang-Won, Lee, Hyun-Ji, Lee, Tae Geol, Jung, Wook Hyun et al. · 2026 · Molecular Therapy: Nucleic Acids
  61. Mechanisms of Invasion and Metastasis: Prometastatic and Antimetastatic Factors
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  62. MicroRNAs and Hepatocellular Carcinoma
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  63. A novel computational system for identification of biological processes from multi-dimensional high-throughput genomic data
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  64. Cancer prevention through miRNAs: miR-206 prevents the initiation and progression of hepatocellular carcinoma by attenuating c-MET signaling and cell-cycle progression via cyclin D1 and CDK6
    Maxine C. Umeh-Garcia, Colleen A. Sweeney · 2018 · Non-coding RNA Investigation
  65. A Cohort Study Using Preoperative IL-6/Stat3/IL-17 And Blood Aminotransferase Levels To Predict Five-Year Survival For Patients After Liver Cancer Resection
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  66. MicroRNAs as Novel Targets in Liver Cancer: Facing the Clinical Challenge
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  67. Noncoding RNAs in liver cancer patients
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  68. MicroRNAs as potential immunotherapeutic modulators in cancer
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  72. miR-499a-5P confers oncogenic roles in breast cancer by targeting SOX6
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  73. MicroRNAs in Liver Regeneration
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  74. Molecular mechanisms of action, diagnostic and therapeutic potential of miRNA-26a
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