Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice
Tomita, Kengo, Teratani, Toshiaki, Suzuki, Takahiro, Shimizu, Motonori, Sato, Hirokazu, Narimatsu, Kazuyuki, Okada, Yoshikiyo, Kurihara, Chie +15 more·2014·Hepatology
Cited by (316)
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- Low Hepatic CEACAM1 Tethers Metabolic Dysfunction Steatohepatitis to AtherosclerosisSacha El Khoury, Sami N. Al Harake, Tya Youssef, Carl E. Risk, Naim G. Helou, Natalie M. Doumet, K. Aramouni, Sami Azar, Sonia M. Najjar, Hilda E. Ghadieh · 2025 · Livers
- Liver immunology: Biological role and clinical significanceStanislav Nikolaevich Kotlyarov · 2025 · World Journal of Hepatology
- Additional file 1 of Identification of functional genes in liver fibrosis based on bioinformatics analysis of a lncRNA-mediated ceRNA networkFeng Zhang, Pei, Siya, Xiao, Meifang · 2024 · Figshare
- The functional role of Claudin-1 as a mediator and therapeutic target in liver fibrogenesis and hepatocarcinogenesisNatascha Roehlen · 2021 · theses.fr (ABES)
- Impact de la stéatohépatite non alcoolique sur le remodelage myocardique et sur les complications cardiovasculairesRaphaël Decoin · 2023
- Purification and Transcriptomic Characterization of Hypertrophied Hepatic Stellate Cells From CDAHFD Mouse LiverMarion Heckmann, Nour El Houda Djerir, Keola Greliche, Pierre‐Henri Commère, Julien Fernandes, Guillaume Sarrabayrouse, Bernard Hainque, Pascal Bigey, Virginie Escriou, Céline Hoffmann · 2026 · The FASEB Journal
- Low concentrations of sorafenib increase dihydrosphingomyelin during antifibrotic processes in human hepatic stellate cellsYeonseo Kim, Baknoon Ham, Yeojin Kim, Byung Hwa Jung, Jinyoung Park, Hyunbeom Lee · 2026 · Biochemical and Biophysical Research Communications
- Annexin A2 Is Associated with Dietary Cholesterol-Induced Metabolic Dysregulation and the Progression of Hepatic FibrosisJiayang Liu, Ling Ou, Haiyan Tai, Yinghan Chai, Lirong Tan, Jie Lin, Bing Li, Ying Cao, Tingting Zhu · 2026 · Metabolites
- Microbial Metabolomic Signatures Reveal Underlying Phenotypic Divergence in Lean and Obese Mice with MASH under Identical Dietary StressTanuja Mohanty, Anil Kumar Baidya, Palok Aich · 2026 · Journal of the American Society for Mass Spectrometry
- Targeting hepatic cholesterol sensing to tackle metabolic dysfunction–associated steatohepatitisMengwei Zang, Yu Li · 2026 · Journal of Clinical Investigation
- Harnessing Natural Products as AMPK Activators: A Promising Therapeutic Avenue for Metabolic Dysfunction-Associated Steatotic Liver DiseaseKun Wang, Hong Shen, Jing Shi, Jiajun Fu · 2026 · Revista Brasileira de Farmacognosia
- Lutein mitigates high-fat-diet induced hepatic lipid accumulation and fibrosis by targeting Hmgcs1 in marine fishYangguang Bao, Jiayun Zhu, Wenli Zhao, Xuran Liu, Tingting Zhu, Peng Sun, Qicun Zhou, Min Jin · 2026 · Marine Life Science & Technology
- Lipotoxicity in MAFLD/MASH: cellular mechanisms and targetable nodesJoseph Tawai, Kairan Zhou, Jing Xiong · 2026 · Targetome
- Hepatic Stellate Cell Heterogeneity in Chronic Liver Fibrosis: Functional States and Translational OpportunitiesRui Chen, Yufei Yang, Guangwen Chen, Xiaobo Cai, Lungen Lu, Qichao Ge · 2026 · Journal of Translational Gastroenterology
- BindingDB Entry 50017780: Synthesis of heterocyclic ring-fused analogs of HMG499 as novel degraders of HMG-CoA reductase that lower cholesterol.BindingDB · 2023 · UC San Diego