Proton pump inhibitors as a risk factor for hepatic encephalopathy and spontaneous bacterial peritonitis in patients with cirrhosis with ascites

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Items 101–190 of 190

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2. A Novel Machine Learning-Based Point-Score Model as a Non-Invasive Decision-Making Tool for Identifying Infected Ascites in Patients with Hydropic Decompensated Liver Cirrhosis: A Retrospective Multicentre Study
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3. Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in patients with cirrhosis and ascites
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4. Proton Pump Inhibitors: Are They a Real Threat to the Patient?
   Sofia A. Xavier, Joana Teixeira Magalhães, José B. Cotter · 2018 · GE Portuguese Journal of Gastroenterology
5. Altered Pathogen Spectrum of Spontaneous Bacterial Peritonitis in Patients Treated With Proton Pump Inhibitors
   P J Kitchen, Sarah Lisa Schütte, Tammo Lambert Tergast, Benjamin Maasoumy, Leonie Braun, Ulrich vor dem Esche, Georg Alexander Häcker, Marcus M. Mücke, Marlene Reincke, Michael Schultheiß et al. · 2026 · Alimentary Pharmacology & Therapeutics
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7. Microbial Approaches to Treat and Prevent Hepatic Encephalopathy
   Mette Munk Lauridsen, Elise Jonasson Nielsen, Jasmohan Singh Bajaj · 2025 · Gastroenterology Clinics of North America
8. Proton Pump Inhibitor Therapy Increases the Risk of Spontaneous Bacterial Peritonitis in Patients with HBV-Related Acute-on-Chronic Liver Failure
   Meng Zhang, Xin Ping Xu, Wei Liu, Zhongwei Zhang, Qiuyu Cheng, Zhongyuan Yang, Tingting Liu, Yunhui Liu, Qin Ning, Tao Chen et al. · 2021 · Advances in Therapy
9. Spontaneous bacterial peritonitis: a prospective Greek multicenter study of its epidemiology, microbiology, and outcomes
   Dimitrios N. Samonakis · 2021 · Annals of Gastroenterology
10. Proton pump inhibitor use and risk of hepatic encephalopathy: A multicentre study
    Simon Johannes Gairing, Chiara Mangini, Lisa Zarantonello, Elise Jonasson Nielsen, Henrike Dobbermann, Philippe Sultanik, Peter Robert Galle, Joachim Labenz, Dominique Thabut, Jens Uwe Marquardt et al. · 2024 · JHEP Reports
11. The association between proton‐pump inhibitor use and recurrence of hepatocellular carcinoma after hepatectomy
    Chun-Ting Ho, Chia‐Chu Fu, Elise Chia‐Hui Tan, Wei‐Yu Kao, Pei‐Chang Lee, Yi‐Hsiang Huang, Teh‐Ia Huo, Ming‐Chih Hou, Jaw‐Ching Wu, Chien‐Wei Su · 2024 · Journal of Gastroenterology and Hepatology
12. The prognosis and incidence of hepatic encephalopathy of patients with liver cirrhosis treated with proton pump inhibitors
    Akira Sakamaki, Kenya Kamimura, Takeshi Yokoo, Akihiko Osaki, Seiichi Yoshikawa, Yoshihisa Arao, Toru Setsu, Hiroteru Kamimura, Nobuo Waguri, Manabu Takeuchi et al. · 2021 · Medicine
13. Proton Pump Inhibitors in Patients with Cirrhosis: Pharmacokinetics, Benefits and Drawbacks
    Gasser El-Azab · 2024 · Current Gastroenterology Reports
14. Gut microbiome composition in patients with liver cirrhosis with and without hepatic encephalopathy: A systematic review and meta-analysis
    Xiaotong Xu, Minjie Jiang, Yunlai Fu, Fang Xie, Jianjun Li, Qinghua Meng · 2025 · World Journal of Hepatology
15. Decompensated cirrhosis: an update of the BSG/BASL admission care bundle
    Stuart McPherson, Nadir Abbas, Michael Allison, Dianne Backhouse, Helen Boothman, Tim Cooksley, Lynsey Corless, Thomas Crame, Timothy Cross, Joanna Henry et al. · 2025 · Frontline Gastroenterology
16. Low dose of propranolol treatment is associated with better survival in cirrhotic patients with hepatic encephalopathy
    Pei‐Chang Lee, Yu‐Ju Chen, Yueh‐Ching Chou, Kuei‐Chuan Lee, Ping‐Hsien Chen, Wei‐Yu Kao, Yi‐Hsiang Huang, Teh‐Ia Huo, Han‐Chieh Lin, Ming‐Chih Hou et al. · 2019 · European Journal of Gastroenterology & Hepatology
17. The gastrointestinal system in the critically ill cirrhotic patient
    Jody C. Olson · 2020 · Current Opinion in Critical Care
18. The impact of proton pump inhibitors in liver diseases and the effects on the liver
    Yuanbin Liu, Ming Kai Chen · 2022 · Journal of Digestive Diseases
19. Bacterial Infections Confer a Risk of Progression to Acute-on-Chronic Liver Failure in Patients with HBV-Related Compensated Cirrhosis During Severe Hepatitis Flares
    Jun Chu, Yanqing Yang, Yujuan Liu, Lingqi Pei, Yihong Zhou, Tao Lu, Yin Zhang, Han Hu, Ying Li, Fangwan Yang et al. · 2022 · Infectious Diseases and Therapy
20. Prescribing Responsibly: Navigating the Tides of Deprescribing in Proton Pump Inhibitor Stewardship
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21. Proton Pump Inhibitor Use and Risk of Hepatic Encephalopathy in Cirrhotic Patients: A Systematic Review and Meta-analysis
    Hasan Jaber, Sandra L. Chehayeb, Janane Nasr, Nader Al Souky, Daly Al-Hadeethi, Hayrettin Okut, Mathew Stotts, William J. Salyers · 2025 · Clinics and Research in Hepatology and Gastroenterology
22. Is the Use of Proton Pump Inhibitors a Predisposing Factor for Pyogenic Liver Abscesses?
    Ahmed Elfiky, Mira Alsheikh, Jeff Hosry, Anum Aqsa, Ahmad Abou Yassine, Liliane S. Deeb · 2021 · Gastroenterology Research
23. Management der dekompensierten Leberzirrhose in der klinischen Akut‑, Notfall- und Intensivmedizin
    Philipp Kasper, Frank Tacke, Guido Michels · 2021 · Medizinische Klinik - Intensivmedizin und Notfallmedizin
24. Letter: proton pump inhibitors and prognosis of cirrhosis – searching for the balance point
    Leonardo de Lucca Schiavon, T. E. Silva, Josiane Fischer, Janaína Luz Narciso-Schiavon · 2016 · Alimentary Pharmacology & Therapeutics
25. Use of Proton Pump Inhibitors Among Patients With Alcohol‐Related Cirrhosis—A Danish Nationwide Cohort Study
    Marine Sølling Ramsing, Morten Daniel Jensen, Peter Jepsen · 2025 · Liver International
26. Bacterial infections in cirrhosis: a narrative review and key points for clinical practice
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27. Association Between Proton Pump Inhibitor Therapy and Spontaneous Bacterial Peritonitis Occurrence in Cirrhotic Patients: A Clinical Review
    Meng Zhang, Wei Liu, Xin Ping Xu, Tao Chen, Junying Qi · 2022 · Current Medical Science
28. Proton Pump Inhibitor Use and Complications of Cirrhosis Are Linked With Distinct Gut Microbial Bacteriophage and Eukaryotic Viral-Like Particle Signatures in Cirrhosis
    Marcela Peña Rodríguez, Andrew Fagan, Masoumeh Sikaroodi, Patrick Martin Gillevet, Jasmohan Singh Bajaj · 2023 · Clinical and Translational Gastroenterology
29. Proton Pump Inhibitor Use Following Esophageal Variceal Ligation and Its Impact on Clinical Outcomes: Real-World Data from the TriNetX Global Collaborative Network
    Nisar A. Amin, Harleen Kaur Chela, Muhammed Mubarak, Mark Ayoub, Ebubekir S. Daglilar · 2025 · Diagnostics
30. Re-Evaluating the Role of Proton Pump Inhibitors After Endoscopic Band Ligation of Esophageal Varices in Cirrhotic Patients: A Systematic Review and Meta-Analysis
    Bernardo de Faria Moraes, Gabriel André Pedral Diniz Leite, Gustavo André Pedral Diniz Leite, Maria Luisa Motta Fonseca, Rodolfo Augusto Assis Rezende, Guilherme Grossi Lopes Cançado · 2025 · The American Journal of Gastroenterology
31. Risk stratification of spontaneous bacterial peritonitis recurrence: integrating acute kidney injury, biomarkers, composite scores, and machine learning models
    Nasser Mousa, Alaa Elmetwalli, Mostafa Abdelsalam, Mohamed Wahba, Mohamed Ahmed Selim, Dina Nour, Eman Abdelkader, Ahmed El-Eraky, Amany Hasson, Ahmed Taha et al. · 2025 · Gut Pathogens
32. Changing Prevalence of Medication Use in People with Cirrhosis: A Retrospective Cohort Study Using Pharmaceutical Benefits Scheme Data
    Kelly Lee Hayward, Rianne A. Weersink, Christina Maresch Bernardes, Carolyn McIvor, Tony Manibur Rahman, Richard Skoien, Paul James Clark, Katherine Anne Stuart, Günter Härtel, Patricia Casarolli Valery et al. · 2023 · Drugs - Real World Outcomes
33. Spontaneous Bacterial Peritonitis and Secondary Bacterial Peritonitis—a Comprehensive Review
    Gabriela N. Kuftinec, Jose Raul Estrada, Kalyan Ram Bhamidimarri · 2020 · Current Hepatology Reports
34. Electroencephalography Signatures for Hepatic Encephalopathy in Cirrhosis Patients Treated with Proton Pump Inhibitors: An Exploratory Pilot Study
    Pan Zhang, Lizhi Zhou, Li Chen, Zhen Zhang, Rui Han, Gangwen Guo, Haocheng Zhou · 2022 · Biomedicines
35. Non-Invasive Methods for the Prediction of Spontaneous Bacterial Peritonitis in Patients with Cirrhosis
    Ngoc Huynh Cao, Phat Tan Ho, Hoang Huu Bui, Thong Duy Vo · 2023 · Gastroenterology Insights
36. Komplikationen der Leberzirrhose – medikamentöse versus interventionelle Therapie
    Lukas Sturm, Martin P. Rossle, Michael Schultheiß · 2019 · DMW - Deutsche Medizinische Wochenschrift
37. Are proton pump inhibitors a threat for spontaneous bacterial peritonitis and hepatic encephalopathy in cirrhosis? Not so fast
    Muhammad Ali Khan, George T. Cholankeril, Colin W. Howden · 2016 · Hepatology
38. Novel machine learning-based point-score model as a non-invasive decision-making tool for infected ascites in patients with hydropic decompensated liver cirrhosis: A retrospective multicentre study.
    Silvia M. Würstle, Alexander Hapfelmeier, Siranush Karapetyan, Fabian Studen, Andriana Isaakidou, Tillman Schneider, Roland Michael Schmid, Stefan von Delius, Felix Gundling, Julian Triebelhorn et al. · 2022 · Research Square
39. PPI efficacy in the reduction of variceal bleeding incidence and mortality, a meta-analysis
    Sheref A. Elseidy, Ahmed Sayed, Ahmed Khaled Awad, Debvarsha Mandal, Mariam Ahmed Osman Mostafa, Aisha Olanike Adigun, Monica Vorla, Zarlakhta Zamani, Amir Iqbal · 2022 · The Egyptian Journal of Internal Medicine
40. Advances in Factors and Risk Prediction of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt
    Lixin Song, Xinyi Qiao, Yu Sun, Hui Yang · 2025 · Portal hypertension & cirrhosis
41. The crucial role of risk factors when dealing with hepatic Encephalopathy
    Lucia Lapenna, Simone Di Cola, M. Merli · 2024 · Metabolic Brain Disease
42. Predictors of Spontaneous Bacterial Peritonitis (SBP) in Liver Cirrhosis: Current Knowledge and Future Frontiers
    Helen Ngo, Raymund Gantioque · 2017 · Open Journal of Gastroenterology
43. Use of prokinetic agents or antibiotics is associated with the occurrence of spontaneous bacterial peritonitis in cirrhotic patients
    Yun‐Cheng Hsieh, Ming‐Hsun Lee, Kuei‐Chuan Lee, Ying‐Ying Yang, Ming‐Chih Hou, Han‐Chieh Lin · 2018 · Journal of the Chinese Medical Association
44. Einsatz von Protonenpumpenhemmern bei Patienten mit Leberzirrhose – eine Umfrage unter Hepatologen in Deutschland
    Thomas Horvatits, Andreas Drolz, Malte H. Wehmeyer, Christian J. Steib, Jonel Trebicka, Ansgar Wilhelm Lohse, Johannes Kluwe · 2019 · Zeitschrift für Gastroenterologie
45. Proton pump inhibitor therapy is associated with reduced survival following first-time transarterial chemoembolization in patients with hepatocellular carcinoma
    Lukas Sturm, Laura Muller, Michael Schultheiss, Benedikt Binder, Jan Patrick Huber, Robert Thimme, Dominik Bettinger · 2020 · European Journal of Gastroenterology & Hepatology
46. Determining the Risk of Spontaneous Bacterial Peritonitisdue to increase use of Proton Pump Inhibitors among cirrhotic patients with ascites
    Bashir Ahmed Shaikh, Zahid Ali Shaikh, Aftab Hussain Shah, Aneel Kumar · 2021 · Pakistan Journal of Medical Sciences
47. Editorial: should the inappropriate use of proton pump inhibitors be a quality assurance issue in cirrhotic patients?
    Jawaid Ahmed Shaw, Jasmohan Singh Bajaj · 2017 · Alimentary Pharmacology & Therapeutics
48. Risks of proton pump inhibitors for patients with cirrhosis: The controversy remains
    Ângelo Zambam de Mattos, Suelen Aparecida da Silva Miozzo, Cristiane Valle Tovo, Ângelo Alves de Mattos · 2017 · Hepatology
49. Proton Pump Inhibitor Use in Patients With Cirrhosis and Its Association With Spontaneous Bacterial Peritonitis
    Morgan Thomas, Cameron Lanier, Kelly L. Covert · 2025 · Journal of Pharmacy Technology
50. Chinese Consensus on Clinical Diagnosis and Management of Covert Hepatic Encephalopathy
    Chinese Society of Gastroenterology, Chinese Medical Association · 2025 · Journal of Digestive Diseases
51. Proton pump inhibitors do not impact on the severity and mortality of the acute-on-chronic liver failure: Andalusian multicentric prospective studymulticentric prospective study
    María del Carmen García Gavilán, Marta Guerrero Misas, Alberto García-García, Marta Casado-Martín, Laura Castillo-Molina, Yolanda María Sanchez-Torrijos, Carmen Sendra, Francisco Rivas‐Ruiz, José Miguel Rosales Zábal · 2025 · Revista Española de Enfermedades Digestivas
52. The effect of proton-pump inhibitor therapy on disease outcomes in inflammatory bowel disease: a population-based cohort study
    Thomas Deleuran, Gry Poulsen, Lone Larsen, Jan Fallingborg, Peter Jepsen, Tine Jess · 2025 · Therapeutic Advances in Gastroenterology
53. Study on the Association between Proton Pump Inhibitor and Onset of Spontaneous Bacterial Peritonitis in Patients with Liver Cirrhosis
    义炜 吴 · 2026 · Advances in Clinical Medicine
54. S2k-Leitlinie Gastrointestinale Blutung der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)
    Autorinnen/Autoren, für die Autoren des DGVS Leitlinienkomitees/for the authors of the DGVS guideline committee, Collaborators · 2026 · Zeitschrift für Gastroenterologie
55. Hepatic encephalopathy syndrome: current aspects of diagnosis and treatment
    Д. И. Трухан · 2016 · Meditsinskiy sovet = Medical Council
56. Vasoconstrictors in combination with proton pump inhibitors as an initial treatment of acute upper gastrointestinal bleeding in liver cirrhosis: is it evidence based?
    Fan Gao, Nahúm Méndez‐Sánchez, Xingshun Qi · 2018 · Annals of Translational Medicine
57. Das Mikrobiom als Drehscheibe für Nebenwirkungen der Protonenpumpenhemmer-Therapie
    Angela Horvath, Vanessa Stadlbauer · 2020 · Zentralblatt für Chirurgie - Zeitschrift für Allgemeine Viszeral- Thorax- und Gefäßchirurgie
58. Impact of proton pump inhibitors on the in-hospital outcome of COVID-19 patients: a retrospective study
    Haijuan Yao, Hongyu Li, Zhuang Ma, Yanyan Wu, Yufu Tang, Hao Meng, Hao Yu, Chengfei Peng, Yue Teng, Quanyu Zhang et al. · 2022 · Therapeutic Advances in Gastroenterology
59. Gastroesophageal Variceal Bleeding Management
    Alberto Zanetto, Guadalupe García–Tsao · 2019 · Springer eBooks
60. Association of gastric acid suppressants with the development of spontaneous bacterial peritonitis in cirrhotic patients with ascites
    Shih‐Lun Teng, Che‐Han Hsu, Chia‐Chun Hsu, Jeng‐Shiann Shin, Jen‐Chieh Huang · 2019 · Advances in digestive medicine
61. Long‐term observation in patients with esophageal varices after endoscopic variceal ligation accompanied with 24‐hour pH monitoring
    Hisashi Hidaka, Satoshi Tanabe, Haruki Uojima, Xue Shao, Shuichiro Iwasaki, Naohisa Wada, Kousuke Kubota, Yoshiaki Tanaka, Takahide Nakazawa, Akitaka Shibuya et al. · 2020 · Hepatology Research
62. Reply
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63. Editorial: is proton pump inhibitor use associated with worse outcomes in patients with liver abscesses?
    James H. Tabibian, Keith D. Lindor · 2018 · Alimentary Pharmacology & Therapeutics
64. Propranolol Treatment is Associated with Better Survival in Cirrhotic Patients with Hepatic Encephalopathy
    Pei-Chang Lee Lee, Yu-Ju Chen, Yueh-Ching Cho, Kuei‐Chuan Lee, Ping‐Hsien Chen, Wei‐Yu Kao, Yi‐Hsiang Huang, Teh‐Ia Huo, Han-Chieh Lin, Ming‐Chih Hou et al. · 2018 · Preprints.org
65. Characteristics of peptic ulcer bleeding in cirrhosis with esophageal and gastric varices
    Zheng Lu, Xiaotian Sun, Jingjing Han, Bo Kyeong Jin, Wenhui Zhang, Yanling Wang, Jun Han, Xuemei Ma, Bo Liu, Xiaoli Yu et al. · 2019
66. Response to Labenz and Labenz
    Chathur Acharya, Jasmohan Singh Bajaj · 2021 · The American Journal of Gastroenterology
67. More Concern About Proton-Pump Inhibitors in Patients with Cirrhosis and Ascites
    Allan S. Brett · 2016 · Journal watch
68. Current Trends in the Management of Spontaneous Bacterial Peritonitis
    Chanda Kendra Ho, Sumeet K. Asrani · 2017 · Current Hepatology Reports
69. Editorial: proton pump inhibitor therapy and liver disease progression—more cause for concern?
    Jane Macnaughtan, Rajiv Jalan · 2017 · Alimentary Pharmacology & Therapeutics
70. Use acid-suppressing drugs appropriately with an individualized approach to minimize the risk of infection
    Adis Medical Writers · 2017 · Drugs & Therapy Perspectives
71. Prescription des médicaments chez un enfant porteur d’une maladie chronique du foie
    Florence Lacaille · 2018 · Elsevier eBooks
72. PPI-Prophylaxe gastrointestinaler Blutungen bei Intensivstationpatienten
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73. Properly prescribed, proton pump inhibitors are largely safe, but precautions are needed to prevent potential problems, overuse and misuse
    Adis Medical Writers · 2019 · Drugs & Therapy Perspectives
74. The association between pre hospital use of proton pump inhibitors and spontaneous bacterial peritonitis in patients presenting with liver cirrhosis.
    Muhammad Hussain Baloch, Riaz Hussain Awan, Seema Nayab, Khadim Hussain Awan, Faqir Muhammad Awan · 2019 · The Professional Medical Journal
75. The concerns of proton pump inhibitors usage in cirrhotic patients with ascites
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76. Management der dekompensierten Leberzirrhose in der klinischen Akut‑, Notfall- und Intensivmedizin
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77. Appropriateness of Proton-Pump Inhibitor Usage among Hospitalized Patients in a Johor Government Hospital
    Tiong Chan Lee · 2022 · IIUM Medical Journal Malaysia
78. Bacterial infection is a risk factor for progression to acute-on-chronic liver failure in patients with severe hepatitis flare of HBV-related compensated liver cirrhosis
    Shide Lin · 2022 · Research Square
79. Association Between Proton Pump Inhibitor Use and Spontaneous Bacterial Peritonitis or Hepatic Encephalopathy in Cirrhotic Patients: A Systematic Review and Meta-analysis
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80. Endoscopic Treatment and Prevention of Acute Variceal Hemorrhage
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81. Letter: Risks of proton pump inhibitor treatment in cirrhotic patients—Authors' reply
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82. Blutungen bei Lebererkrankungen
    Andreas Drolz · 2024 · Medizinische Klinik - Intensivmedizin und Notfallmedizin
83. Proton pump inhibitors versus H2-receptor antagonists in cirrhotic patients: A clinical case and literature perspective
    Saqlain Haider · 2025 · Clinics and Research in Hepatology and Gastroenterology
84. The critical next question: Is the association between proton pump inhibitors and hepatic encephalopathy dose-dependent?
    Muhammad Mohid Haroon · 2025 · Clinics and Research in Hepatology and Gastroenterology
85. Additional file 1 of Meta-analysis of the effects of proton pump inhibitors on the human gut microbiota
    Zhang, Jiayi, Zhang, Chengcheng, Zhang, Qingsong, Yu, Leilei, Chen, Wei, Xue, Yuzheng, Qixiao Zhai · 2023 · Figshare
86. Inibidores da bomba de protões: serão eles uma ameaça à segurança do doente?
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87. Management of Variceal Bleed in Waitlisted Patients
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88. Conclusions in search of a confirmatory analysis: the evidence does not yet justify routine proton pump inhibitors after endoscopic variceal ligation
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89. DYSBIOSIS IN ACUTE-ON-CHRONIC LIVER FAILURE - FROM A PATHOPHYSIOLOGICAL COMPONENT TO A THERAPEUTIC TARGET
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90. Validation of a Machine Learning Model to Noninvasively Exclude Spontaneous Bacterial Peritonitis
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