An assessment of benefits and harms of hepatocellular carcinoma surveillance in patients with cirrhosis
Atiq, Omair, Tiro, Jasmin, Yopp, Adam C., Muffler, Adam, Marrero, Jorge A., Parikh, Neehar D., Murphy, Caitlin, McCallister, Katharine, Singal, Amit G.·2017·Hepatology
Cited by (266)
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- Abbreviated gadoxetic acid–enhanced MRI versus ultrasonography for HCC surveillance in high-risk patients: A randomized trial protocolHyo Jung Park, Jonggi Choi, Dong Wook Kim, Sang Hyun Choi, Won‐Mook Choi, Sung Won Chung, Danbi Lee, Ju Hyun Shim, Han Chu Lee, Y-J Lim et al. · 2025 · Hepatology Communications
- Economic evaluation of biomarker-based surveillance for Hepatocellular Carcinoma in Thai patients with Compensated Liver CirrhosisNutcha Pinjaroen, Wirichada Pan Ngum, Kittiyod Poovorawan, David Wastlund, Fabian Mueller, Peng Lu, Rebecca Sim Shu Yu, Pisit Tangkijvanich · 2026 · PLoS ONE
- Surveillance of patients at risk of liver cancer: Expert opinionsTerry Cheuk‐Fung Yip, Hamish A. Innes, Grace Lai‐Hung Wong, Peter Jepsen · 2026 · Journal of Hepatology
- Development and Validation of a Machine Learning-Based Model Used for Predicting Hepatocellular Carcinoma Risk in Patients with Hepatitis B-Related Cirrhosis: A Retrospective StudyYixin Hou, Jianguo Yan, Ke Shi, Xiaoli Liu, Fangyuan Gao, Tong Wu, Peipei Meng, Min Zhang, Yuyong Jiang, Xianbo Wang · 2024 · OncoTargets and Therapy
- Risk Stratification for Hepatocellular Carcinoma in Patients with Non-alcoholic Fatty Liver DiseaseEmily Truong, Cheng Han, Mark Dhinesh Muthiah, Mazen Noureddin · 2023 · Current Hepatology Reports
- Prediction and surveillance of de novo HCC in patients with compensated advanced chronic liver disease after hepatitis C virus eradication with direct antiviral agentsAshraf Elbahrawy, Hassan Atalla, Abdulla A. Mahmoud, Ahmed Eliwa, Alaa Alsawak, Mohamed Aly Abdelkhalek Alboraie, Ali Madian, Ahmed Alashker, Sadek Mostafa, Ahmed Alwassief et al. · 2023 · Frontiers in Virology
- CON: Hepatocellular Carcinoma Surveillance: In Need of Higher-Quality DataAmit G. Singal · 2017 · The American Journal of Gastroenterology
- ReplyOmair Atiq, Jasmin A. Tiro, Adam Charles Yopp, Adam Muffler, Jorge A. Marrero, Neehar D. Parikh, Caitlin C. Murphy, Katharine McCallister, Amit G. Singal · 2017 · Hepatology
- Cost-effectiveness of an outreach program for HCC screening in patients with cirrhosis: a microsimulation modeling studyTami Gurley, Rubén Hernáez, Vanessa Cerda, Tynaje Thomas, Manasa Narasimman, Sukul Mittal, Mohammed Al-Hasan, Darine Daher, Amit G. Singal · 2025 · EClinicalMedicine
- Should Contrast-Enhanced Computed Tomography and/or Magnetic Resonance Imaging Play a Routine Role in Hepatocellular Carcinoma Surveillance in Patients with Cirrhosis?Jorge A. Marrero · 2025 · Springer eBooks
- MRI management of focal liver lesions: what a beginner cannot fail to knowVincenza Granata, Roberta Fusco, Igino Simonetti, Maria Giovanna Riga, Giuseppe Pellegrino, Serena Carriero, Michele Ahmed Antonio Karaboue, Gianpaolo Carrafiello, Antonella Petrillo, Francesco Izzo · 2025 · Frontiers in Oncology
- Integrative Analysis of Fucosylated Tetra Glycoforms in Hepatocellular Carcinoma: A NanoLC-PRM-MS/MS and Machine Learning ApproachChithravel Vadivalagan, Jie Zhang, Jianliang Dai, Suyu Liu, Amit G. Singal, Kevin Bass, Neehar D. Parikh, David M. Lubman · 2025 · Journal of Proteome Research
- Construction and validation of NSMC-ASIL, a predictive model for risk assessment of malignant hepatic nodules.Jinmei Li, Yue Xu, Hua Liu, Bin Guo, Xiaolan Guo, Yushan Li, Xingliang Jiang, Qiang Wang · 2022 · PubMed Central
- Current updates in HCC screening and treatmentThomas M. Hunold, Anjana A Pillai · 2023 · Clinical Liver Disease
- Molecular profiling in the management of hepatocellular carcinomaNadine Soliman, Ashish Saharia, Maen Abdelrahim, Ashton Anthony Connor · 2023 · Current Opinion in Organ Transplantation
- Hepatocellular Carcinoma from a Hepatologist's PerspectiveGiovanni A. Roldan, Jacquelin Blomker, Elizabeth S. Aby · 2023 · Seminars in Interventional Radiology
- Five‐Gene Expression Formula Accurately Detects Hepatocellular Carcinoma TumorsAram Ansary Ogholbake, Qiang Shawn Cheng · 2025 · Biotechnology Journal
- Beyond the AJR: Shorter Ultrasound Screening Intervals for Hepatocellular Carcinoma Improve Patient OutcomesDavid T. Fetzer · 2021 · American Journal of Roentgenology
- When to Stop Screening—Liver CancerTamar Hamosh Taddei, Janice H. Jou · 2022 · The American Journal of Gastroenterology
- Is Screening for Hepatocellular Carcinoma Effective?Rachel M. Lee, Maria Citarella Russell · 2023 · Advances in Surgery
- The clinical and financial burden of nonhepatocellular carcinoma focal lesions detected during the surveillance of patients with cirrhosisPierre Nahon, Richard Layese, Nathalie Ganne‐Carrié, Cécile Moins, G. Nkontchou, Cendrine Chaffaut, Maxime Ronot, Étienne Audureau, Isabelle Durand‐Zaleski, Pierre-André Natella et al. · 2023 · Hepatology
- Hepatocellular carcinoma: Where are we in 2018?William C. Chapman, Kevin Korenblat, Kathryn Jane Fowler, Nael E. A. Saad, Adeel S. Khan, Vijay Subramanian, Maria B. Majella Doyle, Leigh Anne Dageforde, Benjamin R. Tan, Patrick M. Grierson et al. · 2018 · Current Problems in Surgery
- Editorial: ultrasound surveillance of hepatocellular carcinoma in the 21st century - authors' replyOkeefe L. Simmons, David T. Fetzer, Takeshi Yokoo, Jorge A. Marrero, Adam Charles Yopp, Neehar D. Parikh, Travis G. Browning, Amit G. Singal · 2017 · Alimentary Pharmacology & Therapeutics
- A new tool for estimating liver cancer risk after a hepatitis C virus cureHamish A. Innes, William Lucien Irving · 2020 · HepatoBiliary Surgery and Nutrition
- Hepatocellular carcinoma surveillance in cirrhotic patients: Beyond guidelinesMohammed Omar Khalifa Elsayed · 2023 · Gastroenterology and Functional Medicine
- Can the detection of serum glutathione reductase serve as an effective complement to traditional tumor biomarkers in clinical laboratory medicine for patients with hepatocellular carcinoma?Qingzhu Zheng, Siyan Chen, Jiamiao Weng, Hua Huang, Xiaohong Xu, Yingping Cao · 2025 · BMC Cancer
- Patient Preferences in Hepatocellular Carcinoma Surveillance: A Multisite Conjoint AnalysisKarissa D. Kao, Jonathan P. Troost, Ju Dong Yang, Reena J. Salgia, Sean A. Woolen, Neil J. Mehta, Maarouf A. Hoteit, Prasun K. Jalal, Karim Seif El Dahan, Darine Daher et al. · 2026 · The American Journal of Gastroenterology
- Challenges and adherence to hepatocellular carcinoma surveillance in patients with advanced chronic liver diseaseLuís Neves da Silva, Elisabete Cerqueira, Joana Freitas Ribeiro, Pedro Simões, Sofia Raquel Guimarães Almeida Miguelote, Ana Sofia Maciel Campos da Silva, Beatriz Fernandes, Catarina Melita, Joana Vieira, Sara Pereira et al. · 2026 · Annals of Hepatology
- Hepatocellular carcinoma surveillance in Europe: challenges and lessons from global practiceMaria Qurashi, Marı́a Buti, Grace Lai‐Hung Wong, Huma I Qureshi, Masatoshi Kudo, Tawesak Tanwandee, Chien‐Jen Chen, Ashraf Omar Abdelaziz, Mohamed AbdAllah, Jessica A. Howell et al. · 2026 · The Lancet Regional Health - Europe
- Theranostic and precision medicine for the diagnosis of hepatocellular carcinomaRafael Miret, Amir Riaz, Sikandar G. Khan, Asad Ur Rahman · 2022 · Elsevier eBooks
- National Consensus for Screening, Diagnosis and Management of Hepatocellular Carcinoma in Panama, 2022Moisés Cukier, José M. Cabada-Lee, Jorge David Mendez-Rios, Rafaél Arauz, Erik Araúz, Norberto Carreño, Ivette Clavel, Jan A. Cubilla-Rodríguez, Dafnia De Gracia, Iván Díaz et al. · 2022 · Cancer Studies and Molecular Medicine - Open Journal
- Clinical outcomes of hepatocellular carcinoma surveillance in Melbourne, AustraliaSamuel Hui, Andrew Nguyen, Suong T. T. Le, Anouk T Dev, Sally Bell · 2024 · Internal Medicine Journal
- THE IMPACT OF WORK-LIFE BALANCE ON TURNOVER INTENTIONS: EXPLORING THE MEDIATING ROLE OF JOB SATISFACTIONReni Handayani, Roni Faslah, Maulana Amirul Adha · 2024 · Jurnal Pendidikan Ekonomi Perkantoran dan Akuntansi
- Personalizing Colon Cancer Screening: Role of Age and Comorbid ConditionsMelissa Magrath, Edward Yang, Amit G. Singal · 2017 · Current Colorectal Cancer Reports
- The effect of COVID-19 on liver transplantation: impact, practice patterns, therapeutics, and next stepsAlan L. Hutchison, Anjana A Pillai · 2021 · Current Opinion in Organ Transplantation
- Hepatocellular carcinoma surveillance in non-alcoholic fatty liver disease patientsEmily Truong, Mazen Noureddin · 2022 · Hepatoma Research
- Emphasis on harms of hepatocellular carcinoma surveillance: Just pretending innocence after taking advantage?Zheng Wang, Jun Shu Han, Han Zhang, Mengchao Wu, Tian Yang · 2017 · Hepatology
- Is there a real survival benefit of surveillance for hepatocellular carcinoma in cirrhotic patients?Massimo Colombo, Ana Lleò · 2019 · HepatoBiliary Surgery and Nutrition
- Reply to: “Abbreviated MRI to screen for HCC in patients with cirrhosis. A step forward but a long road ahead”Raghuraman Soundararajan, Pankaj C. Gupta · 2021 · Journal of Hepatology
- Unscheduled screening tests cannot be termed as surveillanceXuejun Xu, Huaizhi Wang, Ping Bie · 2017 · Hepatology
- Ultrasound Screening and Surveillance in Hepatocellular CarcinomaEmily Pang, Alison C. Harris · 2019 · Current Radiology Reports
- ReplyAmit G. Singal · 2019 · Gastroenterology
- Screening for hepatocellular carcinoma in viral liver disease: any new biomarkers on the horizon?Saroja D. Bangaru, Jorge A. Marrero, Amit G. Singal · 2020
- ReplyNicole J. Kim, George N. Ioannou · 2020 · Clinical Gastroenterology and Hepatology
- Hepatitis C-Induced Hepatocellular Carcinoma in the Middle EastSaid A. Al‐Busafi, Khalid M. Al-Naamani · 2021 · Springer eBooks
- ReplyAmit G. Singal, Neehar D. Parikh · 2022 · Hepatology
- ReplyNicole E. Rich, Amit G. Singal · 2018 · Gastroenterology
- Clinical utility of serum chromogranin A as a marker of hepatocellular carcinoma in chronic hepatitis patientsAzza Abdel Rahman Saab, Emad Ahmed Awad, Tarek Mohammed Youssef, MohamedO Aly · 2020 · The Egyptian Journal of Laboratory Medicine
- Interdisciplinary Approach in Hepatobiliary CancersVahid Mansouri, Nima Rezaei · 2022 · Interdisciplinary cancer research
- A CpG-based prediction model for the diagnosis of hepatocellular carcinoma patientsBiyuan Luo, Ning Zhou, Zui Chen, Xianling Liu · 2023 · Research Square
- Role of human body fluid biomarkers in liver cancer: A systematic reviewDahrii Paul, Vigneshwar Suriya Prakash Sinnarasan, Rajesh Das, Dinakara Rao Ampasala, Amouda Venkatesan · 2023 · Elsevier eBooks
- Data from Prediagnostic CT or MRI Utilization and Outcomes in Hepatocellular Carcinoma: SEER-Medicare Database AnalysisMohammad Azharul Karim, Amit G. Singal, Hye‐Chung Kum, Yi‐Te Lee, Sulki Park, Nicole E. Rich, Mazen Noureddin, Ju Dong Yang · 2023
- Evaluation of Hepatocellular Carcinoma Surveillance with Contrast-enhanced MRI in a High-Risk Western European CohortFederico Fiduzi, François E.J.A. Willemssen, Céline van de Braak, Quido G. de Lussanet, Jan N.M. IJzermans, Daniël Bos, Robert Auke de Man, Roy S. Dwarkasing · 2024 · Current Problems in Diagnostic Radiology
- Raising the Bar: Is Hepatocellular Carcinoma Surveillance Warranted for Patients With Alcohol-Associated Cirrhosis?Andrew M. Moon · 2024 · The American Journal of Gastroenterology
- Clinical features of abnormal α-fetoprotein in 15 patients with chronic viral hepatitis B after treatment with antiviral drugsMan-Lei Jiang, Fei Xu, Jinlong Li, Jia-Yu Luo, Jianda Hu, Xi Zeng · 2025 · World Journal of Hepatology
- Should Biomarkers, Such as Alpha Fetoprotein, Play a Routine Role in Hepatocellular Carcinoma Surveillance in Patients with Cirrhosis?Ashwin Rao, Amit G. Singal · 2025 · Springer eBooks
- Should a Randomized Controlled Trial of Hepatocellular Carcinoma Surveillance in Patients with Cirrhosis Be Performed?Ian A.C. Rowe · 2025 · Springer eBooks
- Additional file 1 of Machine learning-based model for predicting the esophagogastric variceal bleeding risk in liver cirrhosis patientsHou, Yixin, Hao Yu, Zhang, Qun, Yang, Yuying, Liu, Xiaoli, Wang, Xianbo, Jiang, Yuyong · 2023 · Figshare
- Psychosocial impact of false-positive surveillance for hepatocellular carcinoma: a qualitative studySamuel Hui, Suong Le, Anouk T Dev, Sally Bell · 2026 · Supportive Care in Cancer
- Net benefit of surveillance varies by hepatocellular carcinoma risk in patients with cirrhosisAkash Patel, Elena I. Gavrila, Sruthi Yekkaluri, Yujin Hoshida, Rubén Hernáez, Amit G. Singal · 2026 · JHEP Reports
- Establishment of a Predictive model for primary liver cancer based on extracellular vesicle microRNA and serum biomarkersJingmin Chang, Yawen Xu, Xiaoli Liu, Chenmin Zhang, Hongjiang Li, Wenfang Yuan, Haojie Zheng, Fumin Feng, Jing Zhang, Dai Erhei · 2026 · Research Square
- A prospective cohort validation study of a multivariable algorithm ASAP for risk stratification of hepatocellular carcinoma surveillanceWei Lun Liou, Siyu Tan, Laurel Jackson, Jason Pik-Eu Chang, Thinesh Lee Krishnamoorthy, Claire Chen, Chin‐Pin Yeo, C H Tan · 2026 · Annals of Hepatology
- FROM BIOMARKERS TO PRECISION SURVEILLANCE: A SOCIO-TECHNICAL REVIEW OF NON-INVASIVE HEPATOCELLULAR CARCINOMA SCREENING IN CIRRHOSISKamil Chudzicki, Michał Babicz, Oliwer Muller, Jagoda Pałubska, Katarzyna Rosa, Agata Słoma, Anna Szot, Dominik Szydełko, Martyna Szymczyk, Paweł Żurek · 2026 · International Journal of Innovative Technologies in Social Science
- A bibliometric analysis of hepatocellular carcinoma screening in high risk populationsChengdian Lan, Dan-Lan Lian, Cui-Ling Huang · 2026 · Discover Oncology
- Performance of Cobas e801 for detection of serum prothrombin induced by vitamin K absence-II in hepatocellular carcinoma: A comparative studyHongkyung Kim, Jinho Heo, Sinyoung Kim, Younhee Park · 2026 · Heliyon
- In silico integration of pan-cancer transcriptomics and curated blood-urine secretome data using explainable machine learning identifies APOF, C9, HP, and OIT3 as biomarker candidates for liver cancerDahrii Paul, Vigneshwar Suriya Prakash Sinnarasan, Rajesh Das, Md Mujibur Rahman Sheikh, Santhosh Manickannan, Amouda Venkatesan · 2026 · In Silico Research in Biomedicine