The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Chemische Aspekte der Penicillin‐Allergie: Die direkte Penicilloylierung von ϵ‐Aminogruppen durch Penicilline bei pH 7, 4
Abstract
Abstract The aminolysis of penicillins by ε‐amino groups at pH 7,4 is demonstrated. It is shown that penicillenic acid, formed spontaneously under these conditions from penicillins, does not contribute significantly to the penicilloylations observed. Penicillin therefore can directly form penicilloylamides under physiological conditions.
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“Beta-lactams are known to be able to act as haptens and bind to amino groups of amino acids, such as lysine [105].”
From The diagnosis of acute interstitial nephritis caused by infection versus antibiotic-induced interstitial nephritis: a narrative review (2024) · cites this paper as [105]
Citations
Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
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STUDIES ON THE MECHANISM OF THE FORMATION OF THE PENICILLIN ANTIGEN
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HYPERSENSITIVITY TO PENICILLENIC ACID DERIVATIVES IN HUMAN BEINGS WITH PENICILLIN ALLERGY
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Parser, C. W., deWeck, A. L., Kern, M., & Eisen, H. N. (1962) · The Journal of Experimental Medicine · doi:10.1084/jem.115.4.803 · Cited by 128
Self-citationLevine, B. B. (1962) · Journal of Medicinal Chemistry · doi:10.1021/jm01240a016 · Cited by 93
The specificity of hemagglutination reactions in human and experimental penicillin hypersensitivity
Thiel, J. A., Mitchell, S., & Parker, C. W. (1964) · Journal of Allergy · doi:10.1016/0021-8707(64)90067-x · Cited by 72
Microbiological Aspects of Penicillin: VI. Procedure for the Cup Assay for Penicillin
Foster, J. W., & Woodruff, H. B. (1944) · Journal of Bacteriology · doi:10.1128/jb.47.1.43-58.1944 · Cited by 67
Levine, B. B. (1961) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(61)90314-9 · Cited by 67
A New Chemical Aspect of Penicillin Allergy: The Direct Reaction of Penicillin with ɛ-Amino-Groups
SCHNEIDER, C. H., & WECK, A. L. D. (1965) · Nature · doi:10.1038/208057a0 · Cited by 66
Self-citationStudies on Penicillin Hypersensitivity
WECK, A. L. D. (2009) · International Archives of Allergy and Applied Immunology · doi:10.1159/000229312 · Cited by 54
Cited by
Idsøe, O., GUTHE, T., Willcox, R. R., & WECK, A. L. D. (1968) · Europe PMC (PubMed Central) · Cited by 540
Mauri-Hellweg, D., Bettens, F., Mauri, D., Brander, C., Hunziker, T., & Pichler, W. J. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.155.1.462 · Cited by 352
Zanni, M. P., von Greyerz, S., Schnyder, B., Brander, K. A., Frutig, K., Hari, Y., Valitutti, S., & Pichler, W. J. (1998) · Journal of Clinical Investigation · doi:10.1172/jci3544 · Cited by 246
Involvement of Drug-Specific T Cells in Acute Drug-Induced Interstitial Nephritis
Spanou, Z., Keller, M., Britschgi, M., Yawalkar, N., Fehr, T., Neuweiler, J., Gugger, M., Mohaupt, M., & Pichler, W. J. (2006) · Journal of the American Society of Nephrology · doi:10.1681/asn.2006050418 · Cited by 151
The Mechanisms of Reactions of β-Lactam Antibiotics
Page, M. I. (1987) · Advances in physical organic chemistry · doi:10.1016/s0065-3160(08)60204-x · Cited by 128
Penicillins and Cephalosporins
WECK, A. L. D. (1983) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-69088-4_16 · Cited by 91
Chemical Aspects of Penicillin Allergy
Schwartz, M. A. (1969) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600580602 · Cited by 81
Drug interaction with T-cell receptors
Depta, J. P. H., Altznauer, F., Gamerdinger, K., Burkhart, C., Weltzien, H. U., & Pichler, W. J. (2004) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2003.11.030 · Cited by 75
High‐affinity glutamate transporters in chronic pain: an emerging therapeutic target
Gegelashvili, G., & Bjerrum, O. J. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12957 · Cited by 47
Schneider, C. H., & WECK, A. L. D. (1967) · Immunochemistry · doi:10.1016/0019-2791(67)90116-4 · Cited by 45
Self-citationPredictive drug allergy testing: an alternative viewpoint
Pichler, W. J. (2001) · Toxicology · doi:10.1016/s0300-483x(00)00399-1 · Cited by 38
Hamilton-Miller, J. M. T., & Abraham, E. P. (1971) · Biochemical Journal · doi:10.1042/bj1230183 · Cited by 36
Schneider, C. H., & WECK, A. L. D. (1966) · Helvetica Chimica Acta · doi:10.1002/hlca.19660490531 · Cited by 34
Self-citationMolecular Basis of Drug Recognition by Specific T–Cell Receptors
von Greyerz, S., Burkhart, C., & Pichler, W. J. (1999) · International Archives of Allergy and Immunology · doi:10.1159/000024192 · Cited by 31
Studies on the direct neutral penicilloylation of functional groups occurring on proteins
Schneider, C. H., & WECK, A. L. D. (1968) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(68)90230-4 · Cited by 29
Self-citationPenicillin‐allergic patients react to penicillin‐modified “self”
Bell, S. J. D., & Pichler, W. J. (1989) · Allergy · doi:10.1111/j.1398-9995.1989.tb02262.x · Cited by 28
Suppression of reaginic antibody formation in guinea pigs by anti-idiotypic antibodies
Geczy, A. F., de Weck, A. L., Geczy, C. L., & Toffler, O. (1978) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(78)90156-2 · Cited by 27
The reaction of penicillin with proteins
Corran, P. H., & Waley, S. G. (1975) · Biochemical Journal · doi:10.1042/bj1490357 · Cited by 26
Gegelashvili, G., & Bjerrum, O. J. (2017) · Advances in neurobiology · doi:10.1007/978-3-319-55769-4_11 · Cited by 25
Virden, R., Bristow, A. F., & Pain, R. H. (1975) · Biochemical Journal · doi:10.1042/bj1490397 · Cited by 22
Zur Kenntnis der Benzylpenicilloinsäure
Schneider, C. H., & WECK, A. L. D. (1967) · Helvetica Chimica Acta · doi:10.1002/hlca.19670500734 · Cited by 18
Self-citationMonovalent elicitation of passive cutaneous anaphylaxis by N1-DNCP-N6-BPO-diaminohexane
Schneider, C. H., Gruden, E., Wälti, M., Toffler, O., de Weck, A. L., & Jost, R. (1979) · Molecular Immunology · doi:10.1016/0161-5890(79)90066-x · Cited by 17
Self-citationMuhammad, A., Zhang, Y., Huang, L., Yuan, Q., Wang, W., Pu, J., Lin, W., Tang, R., & Xiao, X. (2024) · Clinical Kidney Journal · doi:10.1093/ckj/sfae054 · Cited by 13
Bondaruk, J., Curcio‐Vonlanthen, V., & Schneider, C. H. (1995) · Allergy · doi:10.1111/j.1398-9995.1995.tb02584.x · Cited by 12
Self-citationEvaluation of intrinsic and extrinsic penicilloyl-specific immunogenicity of penicillins
Schneider, C. H., & WECK, A. L. D. (1970) · Immunochemistry · doi:10.1016/0019-2791(70)90151-5 · Cited by 12
Self-citationSchneider, C. H., & WECK, A. L. D. (1966) · Helvetica Chimica Acta · doi:10.1002/hlca.19660490533 · Cited by 10
Self-citationAspects of Formation of the D ‐Penicillamine‐Antigenic Determinant from Penicilloyl Compounds
Schneider, C. H., Pfeuti, C., & de Weck, A. L. (1973) · Helvetica Chimica Acta · doi:10.1002/hlca.19730560408 · Cited by 10
Self-citationSchatzmann, U., Wekc, A. L. D., Gerber, H., Lazàry, S., Straub, R., & Pauli, B. U. (1973) · Research in Veterinary Science · doi:10.1016/s0034-5288(18)33807-4 · Cited by 9
BUNDGAARD, H., & HANSEN, J. (1982) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1982.tb04712.x · Cited by 7
The pharmacokinetics of furazlocillin in healthy humans
Hinderling, P. H., Gundert‐Remy, U., Förster, D., & Gau, W. (1983) · Journal of Pharmacokinetics and Biopharmaceutics · doi:10.1007/bf01061765 · Cited by 6
Preparation and Conformational Properties of Benzylpenicilloyl‐oligo‐ L ‐lysine Conjugates
Rolli, H., Luescher, I. F., Schneider, C. H., Toniolo, C., & Bonora, G. M. (1982) · Helvetica Chimica Acta · doi:10.1002/hlca.19820650703 · Cited by 6
Self-citationBlaser, K., Nakagawa, T., & Al, D. W. (1983) · PubMed · Cited by 5
Drug Allergy [ Abridged ]: The Formation of Penicillin Antigens
WECK, A. L. D. (1968) · Proceedings of the Royal Society of Medicine · doi:10.1177/003591576806100917 · Cited by 4
Luescher, I. F., Schneider, C. H., WECK, A. L. D., & Weber, E. A. (1983) · Molecular Immunology · doi:10.1016/0161-5890(83)90119-0 · Cited by 2
Self-citationAntigenic reactivity: Molecular delineation of monohaptenic anaphylactogens
Schneider, C. H., & Guenin, R. (1983) · Biopolymers · doi:10.1002/bip.360220160 · Cited by 1
Self-citationEpitope analysis: N4‐Formylation of the D ‐benzylpenicilloyl antigenic structure
Schneider, C. H., & de Weck, A. L. (1991) · Liebigs Annalen der Chemie · doi:10.1002/jlac.199119910116
Self-citationElks, J., & Ganellin, C. R. (1990) · Springer eBooks · doi:10.1007/978-1-4757-2085-3_16
Metadata
- Authors
- Schneider, C. H., & De Weck, A. L.
- Affiliations
- University of Bern (CH)
- Venue
- Helvetica Chimica Acta
- Publisher
- Wiley
- Published
- 1966-01
- Volume
- 49
- Issue
- 5
- Pages
- 1695-1707
- ISSN
- 0018-019X (ISSN-L)
- 1522-2675
- OpenAlex
- W2088264825
- Cited by
- 37
- References
- 16
- Citations by year
- 2024: 1 · 2017: 1 · 2014: 1
- FWCI
- 5.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Helvetica Chimica Acta (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Drug-Induced Adverse Reactions
- Physical Sciences › Chemistry › Organic Chemistry › Synthesis of β-Lactam Compounds
- Health Sciences › Medicine › Pharmacology (medical) › Historical Medical Research and Treatments
- Keywords
- penicillin allergy, aminolysis, penicillin, pH 7.4, physiological conditions
- MeSH terms
- Animals, Chemistry, Drug Hypersensitivity, Penicillins, Rabbits, Chemical Phenomena
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