Increased expression of AML1‐a and acquired chromosomal abnormalities in childhood acute lymphoblastic leukemia

Gutiérrez‐Angulo, M.; González‐García, J. R.; Meza‐Espinoza, J. P.; Picos‐Cárdenas, V. J.; Esparza‐Flores, M. A.; López‐Guido, B.; Rivera, H.

doi:10.1002/hon.734

Increased expression of AML1‐a and acquired chromosomal abnormalities in childhood acute lymphoblastic leukemia

A semi‐quantitative expression analysis of both AML1‐a and AML1‐total was performed by RT‐PCR in 19 children with acute lymphoblastic leukemia (ALL) at diagnosis. AML1‐a expression was assessed in 16 bone marrow (BM) and 13 peripheral blood (PB) samples whereas AML1‐total was assessed in 17 BM an…