CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer

Mizukami, Yoshiki; Kono, Koji; Kawaguchi, Yoshihiko; Akaike, Hidenori; Kamimura, Kazuyasu; Sugai, Hidemitsu; Fujii, Hideki

doi:10.1002/ijc.23392

CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer

It has been reported that an increased population of regulatory T cells (Tregs) is one of the reasons for impaired anti‐tumor immunity. Recently, Foxp3 has been reported as a reliable marker of Tregs. The authors investigated the frequency of Foxp3 + Tregs within CD4 + cells in TILs, regional lym…