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Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction.
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Citations
Cited by
Instability and decay of the primary structure of DNA
Lindahl, T. (1993) · Nature · doi:10.1038/362709a0 · Cited by 5,679
Self-citationThe DNA Damage Response: Making It Safe to Play with Knives
Ciccia, A., & Elledge, S. J. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.09.019 · Cited by 4,368
Mechanisms of DNA damage, repair, and mutagenesis
Chatterjee, N., & Walker, G. C. (2017) · Environmental and Molecular Mutagenesis · doi:10.1002/em.22087 · Cited by 2,039
“S-adenosylmethionine (SAM), which is used as a methyl donor by methyl transferases during normal methylation reactions, can also spontaneously generate up to 4000 N7methylguanine, 600 N3-methyladenine and 10–30 O6-methylguanine residues per cell per day in mammals (Figure 1d) [Rydberg and Lindahl, 1982; Holliday and H…”
BackgroundMutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli
Walker, G. C. (1984) · Microbiological Reviews · doi:10.1128/mmbr.48.1.60-93.1984 · Cited by 1,770
MUTAGENESIS BY APURINIC/APYRIMIDINIC SITES
Loeb, L. A., & Preston, B. D. (1986) · Annual Review of Genetics · doi:10.1146/annurev.ge.20.120186.001221 · Cited by 901
Metadata
- Authors
- Rydberg, B., & Lindahl, T.
- Venue
- The EMBO Journal
- Published
- 1982-02
- Volume
- 1
- Issue
- 2
- Pages
- 211-216
- ISSN
- 0261-4189 (ISSN-L)
- OpenAlex
- W1791564905
- Cited by
- 409
- References
- 0
- FWCI
- 2.46
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction. https://app.cochat.ai/papers/10.1002/j.1460-2075.1982.tb01149.x
- The paper
- Rydberg, B., & Lindahl, T. (1982). Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction. The EMBO Journal. https://doi.org/10.1002/j.1460-2075.1982.tb01149.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.