Acetaminophen (APAP) 1000 mg, APAP 2000 mg, the combination of APAP 1000 mg plus codeine phosphate 60 mg (APAPCOD), and placebo (PBO) were compared in a 6‐hour, randomized, single‐dose, double‐blind, parallel‐group analgesic trial. All active treatments were statistically superior (p