The DOI matches its Crossref record; 100 of the 100 references it cites were found in a registry or an index.
The long-term costs of traumatic stress: intertwined physical and psychological consequences
Open accessAbstract
The gradual emergence of symptoms following exposure to traumatic events has presented a major conceptual challenge to psychiatry. The mechanism that causes the progressive escalation of symptoms with the passage of time leading to delayed onset post-traumatic stress disorder (PTSD) involves the process of sensitization and kindling. The development of traumatic memories at the time of stress exposure represents a major vulnerability through repeated environmental triggering of the increasing dysregulation of an individual's neurobiology. An increasing body of evidence demonstrates how the increased allostatic load associated with PTSD is associated with a significant body of physical morbidity in the form of chronic musculoskeletal pain, hypertension, hyperlipidaemia, obesity and cardiovascular disease. This increasing body of literature suggests that the effects of traumatic stress need to be considered as a major environmental challenge that places individual's physical and psychological health equally at risk. This broader perspective has important implications for developing treatments that address the underlying dysregulation of cortical arousal and neurohormonal abnormalities following exposure to traumatic stress.
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Cites
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Cited by
Post-traumatic stress disorder.
Yehuda, R., Hoge, C. W., McFarlane, A. C., Vermetten, E., Lanius, R. A., Nievergelt, C. M., Hobfoll, S. E., Koenen, K. C., Neylan, T. C., & Hyman, S. E. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.57 · Cited by 870
Self-citationThe physical health consequences of PTSD and PTSD symptoms: A meta-analytic review
Pacella, M. L., Hruska, B., & Delahanty, D. L. (2013) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2012.08.004 · Cited by 677
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Early psychological intervention following recent trauma: a systematic review and meta-analysis
Roberts, N. P., Kitchiner, N. J., Kenardy, J., Lewis, C. E., & Bisson, J. I. (2019) · European Journal of Psychotraumatology · doi:10.1080/20008198.2019.1695486 · Cited by 200
Metadata
- Authors
- McFARLANE, A. C.
- Venue
- World Psychiatry
- Publisher
- Wiley
- Published
- 2010-02
- Volume
- 9
- Issue
- 1
- Pages
- 3-10
- ISSN
- 1723-8617 (ISSN-L)
- OpenAlex
- W1905774592
- Cited by
- 607
- References
- 100
- FWCI
- 27.79
- Type
- journal article
- Language
- en
- Open access
- bronze
- Licence
- doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 2038 d)
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
