Plasmonic nanoprobes for SERS biosensing and bioimaging
Open accessAbstract
This article provides an overview of the development and application of plasmonic nanoprobes developed in our laboratory for biosensing and bioimaging. We describe the use of plasmonics surface‐enhanced Raman scattering (SERS) gene probes for the detection of diseases using DNA hybridization to target biospecies (HIV gene, breast cancer genes etc.). For molecular imaging, we describe a hyperspectral surface‐enhanced Raman imaging (HSERI) system that combines imaging capabilities with SERS detection to identify cellular components using Raman dye‐labeled silver nanoparticles in cellular systems The detection of specific target DNA sequences associated with breast cancer using “molecular sentinel” nanoprobes and the use of a plasmonic nanosensor to monitor pH in single cells are presented and discussed. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
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References 54 · Cited by 225
- Authors
- Vo‐Dinh, T., Wang, H., & Scaffidi, J.
- Affiliations
- Duke University (US)
- ORCID
- Vo‐Dinh, Tuan
- Venue
- Journal of Biophotonics
- Publisher
- Wiley
- Published
- 2009-12-22
- Volume
- 3
- Issue
- 1-2
- Pages
- 89-102
- ISSN
- 1864-063X (ISSN-L)
- 1864-0648
- PMC
- PMC4022302
- OpenAlex
- W2038411051
- Cited by
- 225
- References
- 54
- Citations by year
- 2026: 2 · 2025: 10 · 2024: 8 · 2023: 7 · 2022: 10 · 2021: 9 · 2020: 9 · 2019: 17 · 2018: 23 · 2017: 18 · 2016: 19 · 2015: 18 · 2014: 12 · 2013: 19 · 2012: 16
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Biophotonics (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Environmental Health Sciences (R01ES014774)
- National Institute of Biomedical Imaging and Bioengineering (R01EB006201)
- Topics
- Physical Sciences › Materials Science › Electronic, Optical and Magnetic Materials › Gold and Silver Nanoparticles Synthesis and Applications
- Physical Sciences › Engineering › Biomedical Engineering › Plasmonic and Surface Plasmon Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Advanced biosensing and bioanalysis techniques
- Keywords
- plasmonic nanoprobes, surface-enhanced Raman scattering, SERS biosensing, SERS imaging, DNA hybridization probes, HIV detection, silver nanoparticles, pH sensing, plasmonic nanosensors
- MeSH terms
- DNA, Humans, Silver, Metal Nanoparticles, Optics and Photonics
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