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Ultra‐high‐strength absorbable self‐reinforced polyglycolide (SR‐PGA) composite rods for internal fixation of bone fractures: In vitro and in vivo study
Abstract
The ultra‐high‐strength, self‐reinforced (SR) absorbable polymeric composites, consisting of reinforcement elements, like fibers, and of matrix polymer which have the same chemical element composition as reinforcement, were defined. A method to manufacture self‐reinforced, absorbable polyglycolide (SR‐PGA) rods of polyglycolide sutures (Dexon) by sintering them partially together at elevated temperature and pressure was presented. The rods with nominal diameters of 1.5 mm, 2.0 mm, 3.2 mm, and 4.5 mm showed initial bending modulus and strength values of 8–15 GPa and 220–405 MPa, respectively. Their initial shear strengths were 165–255 MPa. The smallest rods (diam. 1.5 mm) lost their mechanical strength after implantation in the subcutis of rabbits in 4–5 weeks while the thickest rods retained their strength over 8 weeks. The ultra‐high‐strength SR‐PGA rods were concluded to be suitable for fixation of cancellous bone fractures, osteotomies, and epiphyseal plate fractures where the fixation is not exposed to excessive mechanical stresses and where the loads are predominantly of a shear nature.
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Cited by
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Ramakrishna, S., Mayer, J., Wintermantel, E., & Leong, K. W. (2001) · Composites Science and Technology · doi:10.1016/s0266-3538(00)00241-4 · Cited by 1,642
Athanasiou, K. A., Niederauer, G. G., & Agrawal, C. M. (1996) · Biomaterials · doi:10.1016/0142-9612(96)85754-1 · Cited by 1,497
Biodegradable Materials for Bone Repair and Tissue Engineering Applications
Sheikh, Z., Najeeb, S., Khurshid, Z., Verma, V., Rashid, H., & Glogauer, M. (2015) · Materials · doi:10.3390/ma8095273 · Cited by 782
Mano, J. F., Sousa, R. A., Boesel, L. F., Neves, N. M., & Reis, R. L. (2004) · Composites Science and Technology · doi:10.1016/j.compscitech.2003.09.001 · Cited by 450
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Metadata
- Authors
- Törmälä, P., Vasenius, J., Vainionpää, S., Laiho, J., Pohjonen, T., & Rokkanen, P.
- Venue
- Journal of Biomedical Materials Research
- Publisher
- Wiley
- Published
- 1991-01
- Volume
- 25
- Issue
- 1
- Pages
- 1-22
- ISSN
- 0021-9304 (ISSN-L)
- 1097-4636
- OpenAlex
- W2033299994
- Cited by
- 210
- References
- 0
- FWCI
- 11.14
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Ultra‐high‐strength absorbable self‐reinforced polyglycolide (SR‐PGA) composite rods for internal fixation of bone fractures: In vitro and in vivo study. https://app.cochat.ai/papers/10.1002/jbm.820250102
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- Törmälä, P., Vasenius, J., Vainionpää, S., Laiho, J., Pohjonen, T., & Rokkanen, P. (1991). Ultra‐high‐strength absorbable self‐reinforced polyglycolide (SR‐PGA) composite rods for internal fixation of bone fractures: In vitro and in vivo study. Journal of Biomedical Materials Research. https://doi.org/10.1002/jbm.820250102
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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