Collagen based electrospun materials for skin wounds treatment
Abstract
Materials used for wound care have evolved from simple covers to functional wound dressings with bioactive properties. Electrospun nanofibers show great similarity to the natural fibrillar structure of skin extracellular matrix (ECM); therefore, by mimic, the morphology of ECM, nanofibers show high potential for facilitating the healing of skin injuries. Besides morphology, scaffold composition is another important parameter in the production of bioactive wound dressings. Collagen type I is the main structural protein of skin ECM is biocompatible, biodegradable, and its extraction from animal sources is relatively simple. The fabrication of electrospun wound dressings based on collagen and its blends have been studied for skin tissue engineering applications. This review focus on the new advances of collagen electrospun materials for skin wound treatment. It summarizes the recent research on pristine collagen, collagen blends, and collagen surface modifications on nanofibers mats. Finally, the strategies for three‐dimensional nanofibers production will also be discussed.
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PCL/collagen blend is a promising material for skin and vascular TE.
“PCL/collagen blend is a promising material for skin [153,154,155,156,157,158] and vascular TE [159,160,161].”
From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [153]
Cites
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Electrospun nanostructured scaffolds for bone tissue engineering
Prabhakaran, M. P., Venugopal, J., & Ramakrishna, S. (2009) · Acta Biomaterialia · doi:10.1016/j.actbio.2009.05.007 · Cited by 430 · see citing works
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Multistage ROS-Responsive and Natural Polyphenol-Driven Prodrug Hydrogels for Diabetic Wound Healing
Ni, Z., Yu, H., Wang, L., Huang, Y., Lu, H., Zhou, H., & Liu, Q. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c15686 · Cited by 137 · see citing works
Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review
Vach Agocsova, S., Culenova, M., Birova, I., Omanikova, L., Moncmanova, B., Danisovic, L., Ziaran, S., Bakos, D., & Alexy, P. (2023) · Materials · doi:10.3390/ma16124267 · Cited by 98 · see citing works
- Authors
- Hernández‐Rangel, A., & Martin‐Martinez, E. S.
- Affiliations
- Instituto Politécnico Nacional‐Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada Laboratorio de Biomateriales Ciudad de México Mexico
- Venue
- Journal of Biomedical Materials Research Part A
- Publisher
- Wiley
- Published
- 2021-02-27
- Volume
- 109
- Issue
- 9
- Pages
- 1751-1764
- ISSN
- 1549-3296 (ISSN-L)
- 1552-4965
- OpenAlex
- W3132033143
- Cited by
- 133
- References
- 2
- Citations by year
- 2026: 11 · 2025: 29 · 2024: 31 · 2023: 33 · 2022: 23 · 2021: 6
- FWCI
- 1.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Biomedical Materials Research Part A (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Consejo Nacional de Ciencia y Tecnología (146101)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
- Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
- Physical Sciences › Materials Science › Biomaterials › Collagen: Extraction and Characterization
- Keywords
- collagen, electrospun nanofibers, wound dressings, skin wound healing, type I collagen, extracellular matrix mimicry, skin tissue engineering, bioactive wound dressings
- MeSH terms
- Animals, Collagen, Humans, Skin, Wound Healing, Tissue Engineering, Tissue Scaffolds
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