Thermomechanical properties, collapse pressure, and expansion of shape memory polymer neurovascular stent prototypes
Open accessAbstract
Shape memory polymer stent prototypes were fabricated from thermoplastic polyurethane. Commercial stents are generally made of stainless steel or other alloys. These alloys are too stiff and prevent most stent designs from being able to navigate small and tortuous vessels to reach intracranial lesions. A solid tubular model and a high flexibility laser etched model are presented. The stents were tested for collapse in a pressure chamber. At 37°C, the full collapse pressure was comparable to that of commercially available stents, and higher than the estimated maximum pressure exerted by intracranial arteries. However, there is a potential for onset of collapse, which needs further study. The stents were crimped and expanded, the laser‐etched stent showed full recovery with an expansion ratio of 2.7 and a 1% axial shortening. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2009
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Tubular SMP devices were laser etched for more flexible stents that could navigate through small tortuous vessels; however, resistance to withstand the critical collapse pressure in the vessel at elevated body temperature may not be given in all cases.
“In addition, tubular SMP devices were laser etched for more flexible stents that also could navigate through small tortuous vesselshowever, it has been revealed that resistance to withstand the critical collapse pressure in the vessel at elevated body temperature may not be given in all cases [106].”
From Shape-memory polymers as a technology platform for biomedical applications (2010) · cites this paper as [106]
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References 50 · Cited by 67
- Authors
- Baer, G. M., Wilson, T. S., Small, W., Hartman, J., Benett, W. J., Matthews, D. L., & Maitland, D. J.
- Affiliations
- Lawrence Livermore National Laboratory (US)
- Kaiser Permanente (US)
- University of California Davis Medical Center (US)
- Corresponding author
- Maitland, Duncan J.
- Venue
- Journal of Biomedical Materials Research Part B: Applied Biomaterials
- Publisher
- Wiley
- Published
- 2008-12-23
- Volume
- 90B
- Issue
- 1
- Pages
- 421-429
- ISSN
- 1552-4973 (ISSN-L)
- 1552-4981
- PMC
- PMC3022342
- OpenAlex
- W2149352845
- Cited by
- 67
- References
- 50
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 4 · 2023: 2 · 2022: 4 · 2021: 4 · 2020: 10 · 2019: 5 · 2018: 4 · 2017: 3 · 2016: 4 · 2015: 3 · 2014: 4 · 2013: 1 · 2012: 6
- FWCI
- 4.24
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Biomedical Materials Research Part B Applied Biomaterials (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Biomedical Imaging and Bioengineering (R01EB000462)
- Topics
- Physical Sciences › Engineering › Mechanical Engineering › Advanced Materials and Mechanics
- Physical Sciences › Materials Science › Polymers and Plastics › Polymer composites and self-healing
- Health Sciences › Medicine › Neurology › Intracranial Aneurysms: Treatment and Complications
- Keywords
- shape memory polymers, thermoplastic polyurethane, intracranial stenting, collapse pressure, stent expansion, laser etching, crimping, thermomechanical properties
- MeSH terms
- Models, Theoretical, Polymers, Pressure, Stents, Neovascularization, Physiologic
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