Calcium‐ and FK506‐independent interaction between the immunophilin FKBP51 and calcineurin*

FKBP51 is a member of the immunophilin family having intrinsic peptidyl‐prolyl cis‐trans‐isomerase (PPIase) activity. Its enzymatic activity is inhibited by binding either immunosuppressive agent FK506 or rapamycin. Similar to FKBP12, but at higher concentrations of FK506, FKBP51 has been shown t…