The DOI matches its Crossref record.
Long noncoding RNAs expression in gastric cancer
Abstract
Long noncoding RNAs (lncRNAs) have been involved in the pathogenesis of several human cancers including gastric cancer. In the current study, we selected five lncRNAs namely NEAT1, TUG1, PANDA, UCA1, and GHET1 to assess their expressions in gastric cancer samples compared with adjacent noncancerous tissues (ANCTs) from the same patients. Some previous reports have shown contribution of these lncRNAs in gastric cancer. However, we aimed to explore their associations with patients’ clinicopathological data and their potential as diagnostic biomarkers. Significant associations were found between site of primary tumor and relative expression of all lncRNAs in cancer samples compared with ANCTs. Besides, GHET1 relative expression was associated with lymph node status. The diagnostic power of GHET1 was higher from other lncRNAs. Combination of GHET1, TUG1, UCA1, and PANDA increased the diagnostic power and significance (AUC = 0.8; P < 0.0001). The current study supports participation of lncRNAs in the pathogenesis of gastric cancer and highlights their potential as diagnostic biomarkers.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“they can influence the expression of other genes through multiple mechanisms to cause a wide range of disorders.215–218”
From Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential (2023) · cites this paper as [217]
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 21
- 10.3322/caac.21166 · DOI · Paper page
- 10.18632/oncotarget.19197 · DOI
- 10.1007/s12551‐017‐0379‐y · DOI
- 10.6091/.21.1.24 · DOI
- 10.1016/j.gene.2017.02.031 · DOI
- 10.1186/s13046-016-0420-1 · DOI
- 10.1186/s12967-015-0595-9 · DOI
- 10.7150/jca.19980 · DOI
- Ke H, 2016, NEAT1 is required for survival of breast cancer cells through FUS and miR‐548, Gene Regul Syst Bio, 10, 11
- 10.1186/S40064‐015‐1092‐6 · DOI
- 10.5812/ijcm.9920 · DOI
- 10.1111/febs.12625 · DOI
- Li L‐J, 2014, Long noncoding RNA GHET1 promotes the development of bladder cancer, Int J Clin Exp Pathol, 7, 7196
- 10.1038/srep22366 · DOI
- 10.1515/med-2016-0031 · DOI
- 10.1007/s12094‐015‐1290‐2 · DOI
- 10.3892/mmr.2018.9332 · DOI
- 10.1016/j.biopha.2016.01.025 · DOI
- 10.1002/jcb.26691 · DOI
- 10.1371/journal.pone.0063826 · DOI
- 10.1002/cncr.20966 · DOI
Cited by
Sorted by citations
Yuan, M., Yang, B., Rothschild, G., Mann, J. J., Sanford, L. D., Tang, X., Huang, C., Wang, C., & Zhang, W. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01519-z · Cited by 246
Metadata
- Authors
- Esfandi, F., Taheri, M., Kholghi Oskooei, V., & Ghafouri‐Fard, S.
- Affiliations
- Shahid Beheshti University (IR)
- Department of Medical Genetics Shahid Beheshti University of Medical Sciences Tehran Iran
- Corresponding author
- Taheri, Mohammad
- Ghafouri‐Fard, Soudeh
- Venue
- Journal of Cellular Biochemistry
- Publisher
- Wiley
- Published
- 2019-04-02
- Volume
- 120
- Issue
- 8
- Pages
- 13802-13809
- ISSN
- 0730-2312 (ISSN-L)
- 1097-4644
- OpenAlex
- W2929202984
- Cited by
- 21
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2023: 3 · 2022: 1 · 2021: 2 · 2020: 10 · 2019: 3
- FWCI
- 1.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Cellular Biochemistry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Shahid Beheshti University of Medical Sciences (15202)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer-related molecular mechanisms research
- Health Sciences › Medicine › Oncology › Gastric Cancer Management and Outcomes
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Circular RNAs in diseases
- Keywords
- long non-coding RNA, gastric cancer, NEAT1, TUG1, PANDAS, UCA1, diagnostic biomarkers, clinicopathological features, lymph node metastasis, tumor location, gene expression
- MeSH terms
- Adolescent, Adult, Female, Humans, Male, Middle Aged, RNA, Neoplasm, Stomach Neoplasms, Biomarkers, Tumor, Gene Expression Regulation, Neoplastic, RNA, Long Noncoding
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Long noncoding RNAs expression in gastric cancer. https://app.cochat.ai/papers/10.1002/jcb.28653
- The paper
- Esfandi, F., Taheri, M., Kholghi Oskooei, V., & Ghafouri‐Fard, S. (2019). Long noncoding RNAs expression in gastric cancer. Journal of Cellular Biochemistry. https://doi.org/10.1002/jcb.28653
