Trimethylamine N‐oxide promotes apoE−/− mice atherosclerosis by inducing vascular endothelial cell pyroptosis via the SDHB/ROS pathway

Wu, Peng, Chen, JinNa, Chen, JiaoJiao, Tao, Jun, Wu, ShiYuan, Xu, GaoSheng, Wang, Zuo, Wei, DangHeng +1 more·2020·Journal of Cellular Physiology

Cited by (140)

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  13. Trimethylamine N-oxide (TMAO) disrupts endothelial junction integrity through VE-cadherin Tyr658 phosphorylation in vitro
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  15. Gut microbiota-derived trimethylamine N-oxide contributes to cardiomyocyte pyroptosis and cardiac injury via the tRF-Glu–ANT1–GSDMD axis
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  18. Targeting cholesterol-driven pyroptosis: a promising strategy for the prevention and treatment of atherosclerosis
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  19. Trymethylamine-N-oxide, a gut-derived metabolite, induces myofibroblastic activation of valvular interstitial cells through endoplasmic reticulum stress
    Samanvitha Deepthi Sudi, Sai Drishya Suresh, Tanmayee Kolli, Ana Maria Porras · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  20. Effects of herbal cake-partitioned moxibustion on plasma trimethylamine, trimethylamine-N-oxide, and flavin-containing monooxygenase 3 in atherosclerotic rabbits
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  26. Investigating the anti-atherosclerotic effect and potential mechanism of Sanzi San in ApoE-defcient mice by UHPLC-ESI-QE-Orbitrap-MS based non-targeted metabonomics
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  28. Additional file 1 of Homocysteine promotes atherosclerosis through macrophage pyroptosis via endoplasmic reticulum stress and calcium disorder
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  29. Additional file 1 of A novel pyroptosis-related gene signature exhibits distinct immune cells infiltration landscape in Wilms’ tumor
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  30. Additional file 2 of A novel pyroptosis-related gene signature exhibits distinct immune cells infiltration landscape in Wilms’ tumor
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  31. Additional file 1 of Bone marrow mesenchymal stem cellsderived exosomes stabilize atherosclerosis through inhibiting pyroptosis
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  33. Based on the gut–heart axis: Polygonum capitatum improves atherosclerosis by modulating gut microbiota and TMAO, supporting MCPIP1/p53-associated endothelial protection
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  34. Shenling Jiangzhi formula alleviates atherosclerosis in ApoE−/− mice by inhibiting vascular inflammation via the NF-κB/NLRP3 pathway
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  36. The influence of trimethylamine-n-oxide on the risk of cardiovascular disease progression
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  37. Longitudinal associations of the gut microbiome with arterial stiffness in US adults: findings from the Baltimore Longitudinal Study of Aging
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  38. Endothelium—The regulator of atherosclerosis
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  39. Recent Advances in Gut Microbiome Modulation in Obesity and Longevity
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  40. Anti-obesity function and related comprehensive molecular mechanisms of probiotics: focus more on mitochondrial dysfunction
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