Cancer‐associated fibroblasts induce an aggressive phenotypic shift in non‐malignant breast epithelial cells via interleukin‐8 and S100A8

Lim, Hyesol; Koh, Minsoo; Jin, Hao; Bae, Mijeong; Lee, Seung‐Yeon; Kim, Kyoung Mee; Jung, Joohee; Kim, Hyun Jeong; Park, So Yeon; Kim, Hoe Suk; Moon, Woo Kyung; Hwang, Sejin; Cho, Nam Hoon; Moon, Aree

doi:10.1002/jcp.30364

Cancer‐associated fibroblasts induce an aggressive phenotypic shift in non‐malignant breast epithelial cells via interleukin‐8 and S100A8

Cancer‐associated fibroblasts (CAFs) in the tumor microenvironment have been associated with tumor progression in breast cancer. Although crosstalk between breast cancer cells and CAFs has been studied, the effect of CAFs on non‐neoplastic breast epithelial cells is not fully understood to date. …