Cited by 217Sperm and Testicular FunctionReproductive biology and impacts on aquatic speciesReproductive Biology and Fertility

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Contribution of epididymal secretory proteins for spermatozoa maturation

Dacheux, Jean‐Louis, Gatti, Jean Luc, Dacheux, Françoise·2003·Microscopy Research and Technique

DOI 10.1002/jemt.10312

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Abstract

The final stages of sperm differentiation occur outside the gonad and are not under the genomic control of germ cells. Only sequential interactions with the medium surrounding the sperm are believed to induce the final steps of spermatogenesis. The epididymis, a long tubule with very active secretory and reabsorption functions, is able to create sequential changes in the composition of luminal fluid throughout its length. The chronologies of the changes, which occur on/in the sperm with those in their surrounding environment, are described. Correlations between the highly regionalized epididymal activities and sperm characteristics linked to their survival and fertility potential are presented in this review.

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“In fact, GII activity is significantly reduced when an inflammatory occlusion distally to the epididymis occurs [440–442], in the case of functional deficiency of the latter in non-azoospermic patients [443], as well as a poor ability to bind the zona pellucida, thus suggesting a role of the enzyme also in sperm–egg b…”
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Authors: Dacheux, J., Gatti, J. L., & Dacheux, F.
Affiliations: Centre National de la Recherche Scientifique (FR)
Corresponding author: Dacheux, Jean‐Louis
ORCID: Gatti, Jean Luc
Venue: Microscopy Research and Technique
Publisher: Wiley
Published: 2003-03-27
Volume: 61
Issue: 1
Pages: 7-17
ISSN: 1059-910X (ISSN-L)
1097-0029
DOI: 10.1002/jemt.10312
OpenAlex: W2139412501
Cited by: 217
References: 66
Citations by year: 2026: 2 · 2025: 4 · 2024: 3 · 2023: 7 · 2022: 4 · 2021: 3 · 2020: 7 · 2019: 5 · 2018: 10 · 2017: 13 · 2016: 7 · 2015: 10 · 2014: 8 · 2013: 11 · 2012: 15
FWCI: 2.37
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Microscopy Research and Technique (publishedVersion)
PubMed (publishedVersion)
HAL (submittedVersion)
Topics: Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Reproductive biology and impacts on aquatic species
Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
Keywords: epididymis, epididymal secretory proteins, sperm maturation, sperm differentiation, sperm fertility, sperm survival, spermatogenesis
MeSH terms: Animals, Epididymis, Humans, Male, Sperm Maturation, Epididymal Secretory Proteins, Rats

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Contribution of epididymal secretory proteins for spermatozoa maturation

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