Lack of appropriate stoichiometry: Strong evidence against an energetically important astrocyte-neuron lactate shuttle in brain

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Items 101–168 of 168

1. Development of a Model to Test Whether Glycogenolysis Can Support Astrocytic Energy Demands of Na+, K+-ATPase and Glutamate-Glutamine Cycling, Sparing an Equivalent Amount of Glucose for Neurons
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3. Neuronal α‐amylase is important for neuronal activity and glycogenolysis and reduces in presence of amyloid beta pathology
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4. Oxygen-glucose deprivation in neurons: implications for cell transplantation therapies
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5. Astrocyte-neuron metabolic crosstalk in ischaemic stroke
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6. Interactions of amyloidogenic proteins with mitochondrial protein import machinery in aging-related neurodegenerative diseases
   Ashley L. Reed, Wayne Mitchell, Andrei T. Alexandrescu, Nathan N. Alder · 2023 · Frontiers in Physiology
7. Persistent changes in extracellular lactate dynamics following synaptic potentiation
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8. Psychology and Pathophysiological Outcomes of Eating
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9. Membrane transporters in traumatic brain injury: Pathological, pharmacotherapeutic, and developmental implications
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10. Estradiol selectively regulates metabolic substrates across memory systems in models of menopause
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11. Taurine Increases Zinc Preconditioning‐Induced Prevention of Nitrosative Stress, Metabolic Alterations, and Motor Deficits in Young Rats following Intrauterine Ischemia
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12. Lactate and Ketone Bodies Act as Energy Substrates as Well as Signal Molecules in the Brain
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13. The Feud over Lactate and Its Role in Brain Energy Metabolism: An Unnecessary Burden on Research and the Scientists Who Practice It
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14. Lactate Transport via Glial MCT1 and Neuronal MCT2 Is Not Required for Synchronized Synaptic Transmission in Hippocampal Slices Supplied With Glucose
    Lennart Söder, Felipe Baeza‐Lehnert, Babak Khodaie, Amr Elgez, Lena Noack, Andrea Lewen, Stefan Hallermann, Gernot Poschet, Karin Borges, Oliver Kann · 2025 · Journal of Neurochemistry
15. Astrocyte Regulation of Neuronal Function and Survival in Stroke Pathophysiology
    Bridget R. Boyle, Andrea P. Berghella, Elena Blanco‐Suárez · 2024 · Advances in neurobiology
16. In vivo calibration of genetically encoded metabolite biosensors must account for metabolite metabolism during calibration and cellular volume
    Gerald A. Dienel, Douglas L. Rothman · 2023 · Journal of Neurochemistry
17. Multifactorial Distress, the Warburg Effect, and Respiratory and pH Imbalance in Cancer Development
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18. Untitled work
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19. Fluctuations of extracellular glucose and lactate in the mouse primary visual cortex during visual stimulation
    Alexandria Béland-Millar, Claude Messier · 2018 · Behavioural Brain Research
20. Glial metabolism versatility regulates mushroom body–driven behavioral output inDrosophila
    Ruchira Basu, Thomas Préat, Pierre-Yves Plaçais · 2024 · Learning & Memory
21. Functional activation of pyruvate dehydrogenase in human brain using hyperpolarized [ 1‐13C ]pyruvate
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22. The brain in flux: Genetic, physiologic, and therapeutic perspectives on transporters in the CNS
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23. Rebuttal from Lasse K. Bak and Anne B. Walls
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24. Monocarboxylate Transport in Drosophila Larval Brain during Low and High Neuronal Activity
    Andrés González‐Gutiérrez, Andrés Ibacache, Andrés Esparza, L. Felipe Barros, Jimena A. Sierralta · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
25. Brain Energy Metabolism
    Daniela Calvetti A, Erkki Somersalo · 2022 · Springer eBooks
26. Brain energetics and the connectionist concept in cognitive neuroscience
    Yuri I. Arshavsky · 2023 · Journal of Neurophysiology
27. Rapid and Stable Formation Method of Human Astrocyte Spheroid in a High Viscous Methylcellulose Medium and Its Functional Advantages
    Fumiya Tao, Keita Kitamura, Sanshiro Hanada, Kazuyuki Sugimoto, Tomomi Furihata, Nobuhiko Kojima · 2023 · Bioengineering
28. Relationship between increased serum neurofilament light chain and glial fibrillary acidic protein levels with non‐motor symptoms in patients with Parkinson's disease
    Peixiao Yin, Xuebin Niu, Chenyang Guan, Zixuan Zhang, Yuning Liu, Jinyu Li, Guiyun Cui, Kun Zan, Chuanying Xu · 2024 · Psychogeriatrics
29. Technological advancements to study cellular signaling pathways in inherited retinal degenerative diseases
    Akanksha Roy, Riet Hilhorst, John P. Groten, François Paquet‐Durand, Tushar Tomar · 2021 · Current Opinion in Pharmacology
30. Comparative Evaluation of Hyperpolarized [ 13 C]pyruvate and [ 13 C]lactate for Imaging Neuronal and Glioma Metabolism
    Jun Chen, Maheen Zaidi, Jaideep Chaudhary, Zohreh Erfani, Sarah Al Nemri, Erik J. Plautz, Xiaodong Wen, Erin H. Seeley, Brenda Bartnik‐Olson, Ian R. Corbin et al. · 2025 · ACS Sensors
31. Artificial neurovascular network (ANVN) to study the accuracy vs. efficiency trade-off in an energy dependent neural network
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32. Methods | 13C MRS Measurements of in Vivo Rates of the Glutamate/Glutamine and GABA/Glutamine Neurotransmitter Cycles
    Douglas L. Rothman, Henk M. De Feyter, Graeme F. Mason, Robin A. de Graaf, Fahmeed Hyder, Kevin L. Behar · 2021 · Elsevier eBooks
33. Brain Energy Metabolism
    Daniela Calvetti A, Erkki Somersalo · 2018 · Springer eBooks
34. [ 18 F]FDG functional PET revisited: A new perspective on the temporal dynamics of brain glucose metabolism
    Andreas Hahn, Pia Falb, Matej Murgaš, Sebastian Klug, Murray Bruce Reed, Godber Mathis Godbersen, Magdalena Ponce de León, Christian Milz, Marcus Hacker, Dan Rujescu et al. · 2026 · Journal of Cerebral Blood Flow & Metabolism
35. MGlu5 Dependent Mitochondrial Translocation of PKCδ : A Mechanism Raising Astrocytic Oxidative Metabolism in Response to Extracellular Glutamate
    Kiavasch Mohammad Nejad Farid, Rodrigo Lerchundi, Christine R. Rose, Amin Derouiche · 2025 · Journal of Neurochemistry
36. Voluntary Behavior and Training Conditions Modulate in vivo Extracellular Glucose and Lactate in the Mouse Primary Motor Cortex
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37. Astrocytes take the stage in a tale of signaling-metabolism coupling
    Lasse K. Bak · 2017 · Journal of Biological Chemistry
38. Fluxes of Lactate Into, From, and Among Gap Junction-Coupled Astroglia and Their Interaction With Noradrenaline
    Gerald A. Dienel · 2017 · Elsevier eBooks
39. Interplay between Energy Supply and Glutamate Toxicity in the Primary Cortical Culture
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40. Lactate Dehydrogenase Inhibition Reverts the Fatty Acid‐Induced Neurotoxic Phenotype of Astrocytes
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41. Possible mechanisms of HIV neuro-infection in alcohol use: Interplay of oxidative stress, inflammation, and energy interruption
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42. Starvation Induces Upregulation of Monocarboxylate Transport in Glial Cells at the Drosophila Blood–Brain Barrier
    Andrés González‐Gutiérrez, Jorge Gaete, Andrés Esparza, Andrés Ibacache, Esteban G. Contreras, Jimena A. Sierralta · 2025 · Glia
43. Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Male Mice Consuming Alcohol Attenuates Glycolysis
    Yann Ehinger, Sophie Laguesse, Khanhky Phamluong, Alexandra Salvi, Yoshitaka J. Sei, Zachary W. Hoisington, Drishti Soneja, Sowmya Gunasekaran, Ken Nakamura, Dorit Ron A · 2025 · Nature Communications
44. Effect of Diet as a Factor of Exposome on Brain Function
    Anna Fedotova, Alisa B. Tiaglik, Alexey V. Semyanov · 2021 · Journal of Evolutionary Biochemistry and Physiology
45. Hyperpolarized [1-13C]pyruvate Magnetic Resonance Spectroscopy Shows That Agmatine Increased Lactate Production in the Brain of Type 2 Diabetic Mice
    Young‐Suk Choi, Jae Eun Song, Eosu Kim, Chul Hoon Kim, Jong Eun Lee, Ho‐Taek Song · 2023 · Yonsei Medical Journal
46. Energy Metabolism | Brain Energy Metabolism
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47. Role of Astrocytic Serine in Learning and Memory and its Implications in Alzheimer's Disease.
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48. On consciousness in animals and in artificial intelligence
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49. Quantifying Compartment-Specific Protein Translocation in Astrocytes by Object-Oriented Image Analysis: Mitochondrial Translocation of PKCδ
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50. Die Bedeutung des Laktats im historischen Kontext
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51. Fructose 1,6-Bisphosphatase 2-Camk2 Interaction Is an Integral Mechanism of Long-Term Potentiation
    Przemysław Duda, Tomasz Wójtowicz, Jakub Janczara, Daniel Krowarsch, Aleksandra Anna Czyrek, Agnieszka Gizak, Dariusz Rakus · 2020 · Preprints.org
52. THE ROLE OF MEMBRANE TRANSPORTERS IN TRAUMATIC BRAIN INJURY: INTERVENTIONAL AND GENETIC INVESTIGATIONS
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53. Estudio de la regulación del metabolismo de la glucosa por la actividad sináptica
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54. Conductor of the Astrocyte-Neuron Metabolic Orchestra
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55. Putative role of cGMP-dependent protein kinase G in inherited retinal degeneration: modulators and biomarkers
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56. Neuro–glia communication and glycolysis
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57. Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Mice Consuming Alcohol Attenuates Glycolysis
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58. Optic Nerve Astrocytes
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59. Modifications métaboliques lors de l'activation cérébrale : suivi par spectroscopie de résonance magnétique nucléaire du proton et du carbone 13
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60. Study of vesicular glycolysis in health and Huntington's Disease
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61. Astrocytes in the visual layers of the superior colliculus : properties and role in visual processing
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62. Pentose Phosphate Pathway Is Critical for Providing Energy by Bypassing 6-Phosphofructo-1-Kinase (PFK1) During Increased Neuronal Activity
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65. Action potential-induced changes in O 2 consumption, NADH regeneration, and mitochondrial membrane potential in adult mouse spinal motor neurons
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66. Written in the Stars: Astrocyte Biology From Evolution to Disease
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68. Metabolic and redox modulation by 2-deoxy-D-glucose and sodium selenite protects against pentylenetetrazole-kindled seizures, neuroinflammation and cognitive dysfunction
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