The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Correlations between mechanical stress history and tissue differentiation in initial fracture healing
Abstract
A general theory for the role of intermittently imposed stresses in the differentiation of mesenchymal tissue is presented and then applied to the process of fracture healing. Two‐dimensional finite element models of a healing osteotomy in a long bone were generated and the stress distributions were calculated throughout the early callus tissue under various loading conditions. These calculations were used in formulating theoretical predictions of tissue differentiation that were consistent with the biochemical and morphological observations of previous investigators. The results suggest that intermittent hydrosatic (dilatational) stresses may play an important role in influencing revascularization and tissue differentiation and determining the morphological patterns of initial fracture healing.
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Citations
Cites
Regulation of bone formation by applied dynamic loads.
Rubin, C. T., & Lanyon, L. E. (1984) · The Journal of Bone & Joint Surgery · doi:10.2106/00004623-198466030-00012 · Cited by 1,558
The influence of induced micromovement upon the healing of experimental tibial fractures
Goodship, A., & Kenwright, J. (1985) · The Journal of Bone and Joint Surgery. British volume · doi:10.1302/0301-620x.67b4.4030869 · Cited by 903
Physical and biological aspects of fracture healing with special reference to internal fixation.
Sm, P. (1979) · PubMed · Cited by 678
Pauwels, F. (1980) · Springer eBooks · doi:10.1007/978-3-642-67138-8 · Cited by 643
Carter, D. R., Fyhrie, D. P., & Whalen, R. T. (1987) · Journal of Biomechanics · doi:10.1016/0021-9290(87)90058-3 · Cited by 518
Self-citationThe Biochemistry and Physiology of Bone
Chalmers, J. (1973) · The Journal of Bone and Joint Surgery. British volume · doi:10.1302/0301-620x.55b2.444 · Cited by 354
Gesammelte Abhandlungen über Entwickelungsmechanik der Organismen / von Wilhelm Roux.
Roux, W. (1895) · W. Engelmann eBooks · doi:10.5962/bhl.title.9169 · Cited by 336
Current concepts of internal fixation of fractures
Tubbs, N. (1981) · Injury · doi:10.1016/0020-1383(81)90078-4 · Cited by 326
On the mathematical analysis of stress in the human femur
Rybicki, E. F., Simonen, F. A., & Weis, E. B. (1972) · Journal of Biomechanics · doi:10.1016/0021-9290(72)90056-5 · Cited by 286
Influences of Mechanical Stress on Prenatal and Postnatal Skeletal Development
CARTER, D. R., ORR, T. E., FYHRIE, D. P., & SCHURMAN, D. J. (1987) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-198706000-00034 · Cited by 268
Self-citation
Cited by
Modelling bone tissue fracture and healing: a review
Doblaré, M., Garcı́a, J. M., & Gómez, M. J. (2004) · Engineering Fracture Mechanics · doi:10.1016/j.engfracmech.2003.08.003 · Cited by 504
Pobloth, A.-M., Checa, S., Razi, H., Petersen, A., Weaver, J. C., Schmidt-Bleek, K., Windolf, M., Tatai, A. Á., Roth, C. P., Schaser, K.-D., et al. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aam8828 · Cited by 312
Glatt, V., Evans, C. H., & Tetsworth, K. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2016.00678 · Cited by 194
Finite Element Method (FEM), Mechanobiology and Biomimetic Scaffolds in Bone Tissue Engineering
Boccaccio, A., Ballini, A., Pappalettere, C., Tullo, D., Cantore, S., & Desiate, A. (2011) · International Journal of Biological Sciences · doi:10.7150/ijbs.7.112 · Cited by 178
Numerical simulation of callus healing for optimization of fracture fixation stiffness
Steiner, M., Claes, L., Ignatius, A., Simon, U., & Wehner, T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0101370 · Cited by 58
Metadata
- Authors
- Carter, D. R., Blenman, P. R., & Beaupré, G. S.
- Venue
- Journal of Orthopaedic Research
- Publisher
- Wiley
- Published
- 1988-09
- Volume
- 6
- Issue
- 5
- Pages
- 736-748
- ISSN
- 0736-0266 (ISSN-L)
- 1554-527X
- OpenAlex
- W2059107467
- Cited by
- 406
- References
- 19
- FWCI
- 1.39
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Correlations between mechanical stress history and tissue differentiation in initial fracture healing. https://app.cochat.ai/papers/10.1002/jor.1100060517
- The paper
- Carter, D. R., Blenman, P. R., & Beaupré, G. S. (1988). Correlations between mechanical stress history and tissue differentiation in initial fracture healing. Journal of Orthopaedic Research. https://doi.org/10.1002/jor.1100060517
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
