An Evaluation of the Utility of Physiologically Based Models of Pharmacokinetics in Early Drug Discovery

Parrott, Neil, Paquereau, Nicolas, Coassolo, Philippe, Lavé, Thierry·2005·Journal of Pharmaceutical Sciences

Cited by (108)

Items 101–108 of 108

  1. Application of Physiologically Based Pharmacokinetic Modeling In Predicting Drug-Drug Interactions For Sarpogrelate Hydrochloride In Humans
    Jee Sun Min, D. Kim, J.B. Park, H Heo, Soo Hyeon Bae, Jae Hong Seo, Euichaul Oh, Soo Kyung Bae · 2016 · Clinical Therapeutics
  2. CHARACTERIZATION OF RENAL SECRETION IN RENAL TRANSPLANT PATIENTS
    Hari Varun Kalluri · 2018 · D-Scholarship@Pitt (University of Pittsburgh)
  3. Putting it All Together
    Pamela Berry, Neil John Parrott, Micaela B. Reddy, Pascale David‐Pierson, Thierry Lavé · 2009 · Methods and principles in medicinal chemistry
  4. Computational Modeling of Drug Oral Bioavailability
    Lon Wolf R. Fong, Beibei Huang, Rajan R. Chaudhari, Shuxing Zhang · 2023 · Wiley eBooks
  5. Correlation between cell- and tissue-based in vitro models for drug permeability screening with in vivo situation: modeling and functional extrapolation
    Paulo Jorge Pereira Alves Paixão, Luís F. Gouveia, José Morais, Nuno Elvas Silva · 2024 · Elsevier eBooks
  6. Integrated Pharmacokinetic Analysis in Discovery
    Emile P. Chen · 2025
  7. Prediction variability in physiologically based pharmacokinetic modeling of tissue disposition under deep uncertainty
    Mustafa Farahat, D T Flaherty, Zachary Fox, Belinda Sena Akpa · 2026 · npj Systems Biology and Applications
  8. BindingDB Entry 50044281: Reductions in log P improved protein binding and clearance predictions enabling the prospective design of cannabinoid receptor (CB1) antagonists with desired pharmacokinetic properties.
    BindingDB · 2015 · UC San Diego