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Application of surface‐enhanced Raman spectroscopy to biological systems

Cotton, Therese M., Kim, Jae‐Ho, Chumanov, George D.·1991·Journal of Raman Spectroscopy

Abstract

This review summarizes the literature relating to the application of surface‐enhanced Raman scattering (SERS) and surface‐enhanced resonance Raman scattering (SERRS) techniques to the study of biological molecules. The emphasis is on publications that have appeared during the period from 1985 to 1991. The review is divided into six major parts. First, a brief overview of the current understanding of the mechanistic aspects of SERS/SERRS is given, with an emphasis on the relationship between theoretical predictions and experimental results. The most common experimental systems (colloids, metal island films, and electrodes) are described. Studies of biological systems are described in the second (small molecules), third (DNA and proteins) and fourth (membranes proteins and membrane preparations) sections. In the fifth or conclusion section, the potential use of SERS or SERRS as a method for obtaining spectra of native biological molecules is evaluated. Finally, the sixth section describes advances in Raman instrumentation in terms of their possible impact on future applications of SERS/SERRS techniques to biological molecules.

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Metadata

Authors
Cotton, T. M., Kim, J., & Chumanov, G. D.
Venue
Journal of Raman Spectroscopy
Publisher
Wiley
Published
1991-12
Volume
22
Issue
12
Pages
729-742
ISSN
  • 0377-0486 (ISSN-L)
  • 1097-4555
OpenAlex
W2061543438
Cited by
200
References
2
FWCI
5.93
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Application of surface‐enhanced Raman spectroscopy to biological systems. https://app.cochat.ai/papers/10.1002/jrs.1250221203
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Cotton, T. M., Kim, J., & Chumanov, G. D. (1991). Application of surface‐enhanced Raman spectroscopy to biological systems. Journal of Raman Spectroscopy. https://doi.org/10.1002/jrs.1250221203

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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