Sudden sensorineural hearing loss is correlated with an increased risk of acute myocardial infarction: A population-based cohort study
Abstract
Objectives/hypothesis Previous studies have indicated that hypercholesterolemia and a high burden of cardiovascular risk factors are associated with the development of sudden sensorineural hearing loss (SSHL). The purpose of this study was to test the hypothesis that SSHL is a risk factor for the development of myocardial infarction (MI). Study design A retrospective cohort study. Methods Using the Taiwan Longitudinal Health Insurance Database, we compared patients diagnosed with SSHL between January 1, 2001, and December 31, 2006, (N = 44,830) with age-matched controls (1:1) (N = 44,830). We followed up on each patient until the end of 2009 to evaluate the incidence of MI for a minimum period of 3 years after their initial SSHL diagnosis. Results We found that after adjusting for potential confounds with an adjusted hazard ratio (HR) of 1.254 (95% confidence interval, 1.092-1.440, P Conclusions SSHL may confer an independent risk of MI. This observation may prompt the early detection and timely treatment of patients at a high risk of MI.
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Several studies have reported an association between ISSNHL and DM.
“Several studies have reported an association between ISSNHL and DM [25-29]”
From Prognostic Factors Associated with Recovery from Recurrent Idiopathic Sudden Sensorineural Hearing Loss: Retrospective Analysis and Systematic Review (2022) · cites this paper as [26]
ISSNHL has been reported to be associated with a history of hypertension, chronic kidney disease, diabetes mellitus, hypercholesterolemia, and stroke.
“ISSNHL has been reported to be associated with a history of hypertension (HTN), chronic kidney disease, diabetes mellitus (DM), hypercholesterolemia, and stroke [25-29].”
From Prognostic Factors Associated with Recovery from Recurrent Idiopathic Sudden Sensorineural Hearing Loss: Retrospective Analysis and Systematic Review (2022) · cites this paper as [26]
Cited by
Sorted by citations
Jeon, S. Y., Kang, D. W., Kim, S. H., Byun, J. Y., & Yeo, S. G. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11051453 · Cited by 9 · see citing works
- Authors
- Lin, C., Lin, S., Lin, Y., Weng, S., & Lee, T.
- Affiliations
- University of California, Berkeley (US)
- University of British Columbia (CA)
- Chi Mei Medical Center (TW)
- Corresponding author
- Lin, Yung‐Song
- Venue
- The Laryngoscope
- Publisher
- Wiley
- Published
- 2013-07-08
- Volume
- 123
- Issue
- 9
- Pages
- 2254-2258
- ISSN
- 0023-852X (ISSN-L)
- 1531-4995
- OpenAlex
- W1487119466
- Cited by
- 49
- References
- 0
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 2 · 2023: 3 · 2022: 3 · 2021: 2 · 2020: 6 · 2019: 1 · 2018: 6 · 2017: 3 · 2016: 9 · 2015: 7 · 2014: 2 · 2013: 1
- FWCI
- 3.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Laryngoscope (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- sudden sensorineural hearing loss, acute myocardial infarction, cardiovascular risk, hypercholesterolemia, cardiovascular risk factors, incidence, age-stratified risk, Taiwan Longitudinal Health Insurance Database
- MeSH terms
- Aged, Hearing Loss, Sudden, Female, Hearing Loss, Sensorineural, Humans, Longitudinal Studies, Male, Middle Aged, Myocardial Infarction, Prognosis, Reference Values, Retrospective Studies, Risk Factors, Severity of Illness Index, Taiwan, Comorbidity, Prevalence, Survival Rate, Confidence Intervals, Poisson Distribution, Proportional Hazards Models, Case-Control Studies, Age Distribution, Sex Distribution, Statistics, Nonparametric, Kaplan-Meier Estimate
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