5‐ALA in the management of malignant glioma

Cited by (234)

Items 101–200 of 234

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2. Spectral library and method for sparse unmixing of hyperspectral images in fluorescence guided resection of brain tumors
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3. Intraoperative fluorescence redefining neurosurgical precision
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4. Predictors of therapeutic efficacy of 5-aminolevulinic acid-based photodynamic therapy in human prostate cancer
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5. Interrelation between Spectral Online Monitoring and Postoperative T1-Weighted MRI in Interstitial Photodynamic Therapy of Malignant Gliomas
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6. Development and validation of a triple-LED surgical loupe device for fluorescence-guided resections with 5-ALA
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7. The Combined Use of 5-ALA and Chlorin e6 Photosensitizers for Fluorescence-Guided Resection and Photodynamic Therapy under Neurophysiological Control for Recurrent Glioblastoma in the Functional Motor Area after Ineffective Use of 5-ALA: Preliminary Results
   Elizaveta I. Kozlikina, И. С. Трифонов, Mikhail Vladimirovich Sinkin, Vladimir V. Krylov, Victor B. Loschenov · 2022 · Bioengineering
8. A Data-Driven Approach to Predicting 5-Aminolevulinic Acid–Induced Fluorescence and World Health Organization Grade in Newly Diagnosed Diffuse Gliomas
   Michael Müther, Mohammed Jaber, Timothy D. Johnson, Daniel A. Orringer, Walter Stummer · 2022 · Neurosurgery
9. The role of Shikonin in improving 5-aminolevulinic acid-based photodynamic therapy and chemotherapy on glioblastoma stem cells
   Maxim Werner, Chen Lyu, Birgit Stadlbauer, Isabel Schrader, Alexander Büchner, Herbert G. Stepp, Ronald C Sroka, Heike Pohla · 2022 · Photodiagnosis and Photodynamic Therapy
10. Technical Pearls to Effectively Use 5-ALA in Fluorescence-Guided Tumor Resection—5 Lessons from the Operating Room
    Giuseppe Maria Della Pepa, Grazia Menna, Alessandro Olivi · 2023 · Brain Sciences
11. Immunomodulatory Effects by Photodynamic Treatment of Glioblastoma Cells In Vitro
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12. The Dilemma of Cure and Damage in Oligodendroglioma: Ways to Tip the Balance Away from the Damage
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13. Elevated cellular PpIX potentiates sonodynamic therapy in a mouse glioma stem cell-bearing glioma model by downregulating the Akt/NF-κB/MDR1 pathway
    Kenji Shono, Yoshifumi Mizobuchi, Izumi Yamaguchi, Kohei Nakajima, Yuri Fujiwara, Toshitaka Fujihara, Keiko T. Kitazato, Kazuhito Matsuzaki, Yoshihiro Uto, Oltea Sampetrean et al. · 2021 · Scientific Reports
14. The NXDC-MEN-301 Study on 5-ALA for Meningiomas Surgery: An Innovative Study Design for the Assessing the Benefit of Intra-Operative Fluorescence Imaging
    Walter Stummer, Markus Holling, Bernard R. Bendok, Michael A. Vogelbaum, Ashley Cox, Sara L. Renfrow, Georg Widhalm, Alan M. Ezrin, Salvatore DeSena, Murray L. Sackman et al. · 2022 · Brain Sciences
15. 5-Aminolevulinic acid-mediated photodynamic activity in patient-derived cholangiocarcinoma organoids
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16. Cerebral Taenia crassiceps larvae infection in a 71-year-old immunocompetent male
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17. Raman and autofluorescence spectroscopy for in situ identification of neoplastic tissue during surgical treatment of brain tumors
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18. Preoperative 5-aminolevulinic acid administration for brain tumor surgery is associated with an increase in postoperative liver enzymes: a retrospective cohort study
    Jun Hyun Kim, Hyun‐Kyu Yoon, Hyung‐Chul Lee, Hee‐Pyoung Park, Chul‐Kee Park, Yun‐Sik Dho, Jung‐Won Hwang · 2019 · Acta Neurochirurgica
19. 5-Aminolevulinic acid for fluorescence-guided surgery in pancreatic cancer: Cellular transport and fluorescence quantification studies
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20. Enhance Fluorescence Imaging and Remove Motion Artifacts by Combining Pixel Tracking, Interleaved Acquisition, and Temporal Gating
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21. Efficacy of interstitial photodynamic therapy using talaporfin sodium and a semiconductor laser for a mouse allograft glioma model
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22. Innovations in the Diagnosis and Surgical Management of Low-Grade Gliomas
    Rafael Uribe-Cardenas, Alexandra Giantini-Larsen, Andrew L. A. Garton, Rupa Gopalan Juthani, Theodore H. Schwartz · 2022 · World Neurosurgery
23. Laser-induced fluorescence diagnosis of stomach tumor
    Maxim V. Loshchenov, V.V. Levkin, Nina A. Kalyagina, Kirill G. Linkov, Sergey S. Kharnas, Kanamat T. Efendiev, Pavel Kharnas, Victor B. Loschenov · 2020 · Lasers in Medical Science
24. Unraveling of Functional Activity of Primary Hippocampal Neuron-Glial Networks in Photodynamic Therapy Based on Tetracyanotetra(aryl)porphyrazines
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25. Compact and contactless reflectance confocal microscope for neurosurgery
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26. TCGA mRNA Expression Analysis of the Heme Biosynthesis Pathway in Diffusely Infiltrating Gliomas: A Comparison of Typically 5-ALA Fluorescent and Non-Fluorescent Gliomas
    Mario Mischkulnig, Barbara Kiesel, Daniela Lötsch, Thomas Roetzer-Pejrimovsky, Martin Borkovec, Lisa I. Wadiura, Petra Andreea Mercea, Florian J. Jaklin, Shawn L. Hervey‐Jumper, Karl Rössler et al. · 2020 · Cancers
27. A novel PDT: 5-aminolevulinic acid combined 450 nm blue laser photodynamic therapy significantly promotes cell death of HR-HPV infected cells
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28. A review of biomodified or biomimetic polymer dots for targeted fluorescent imaging and disease treatments
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29. Epidemiología y caracterización general de los tumores cerebrales primarios en el adulto
    María Isabel Ocampo-Navia, Juan Carlos Gómez Vega, Oscar Hernando Feo Lee · 2018 · Universitas Médica
30. Optical Methods for Brain Tumor Detection: A Systematic Review
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31. 5-aminolevulinic acid induced photodynamic reactions in diagnosis and therapy for female lower genital tract diseases
    Yuqing Chen, Peng Guo, Lihong Chen, Dalin He · 2024 · Frontiers in Medicine
32. Lipoprotein-inspired in situ activatable photo-theranostic nitrobenzoselenadiazole-cholesterol for overcoming glioblastoma
    Jong Min An, Yeon Jin Lim, Jiho Rhim, Kyung Oh Jung, Dokyoung Kim · 2025 · Biomaterials
33. Detection improvement of gliomas in hyperspectral imaging of protoporphyrin IX fluorescence – in vitro comparison of visual identification and machine thresholds
    Samu J.R. Lehtonen, Hana Vrzáková, Jussi J. Paterno, Sami Puustinen, Roman Bednarik, Markku Hauta‐Kasari, Hideaki Haneishi, Arto Immonen, Juha E. Jääskeläinen, Olli‐Pekka Kämäräinen et al. · 2022 · Cancer Treatment and Research Communications
34. Integrating clinical access limitations into iPDT treatment planning with PDT-SPACE
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35. Fully Implantable and Retrievable Upconversion Waveguides for Photodynamic Therapy in Deep Tissue
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36. Investigation of the therapeutic effect of 5-aminolevulinic acid based photodynamic therapy on hepatocellular carcinoma
    Özge Özten, Gamze Güney Eskiler, Fatih Sönmez, Mustafa Zahid Yıldız · 2021 · Lasers in Medical Science
37. Suppression of tumour growth from transplanted astrocytoma cells transfected with luciferase in mice by bioluminescence mediated, systemic, photodynamic therapy
    Jane Ng, Nico V. Henriquez, Neil D. Kitchen, Norman R. Williams, Marco R. Novelli, Dahmane Oukrif, Alexander John MacRobert, Stephen G. Bown · 2023 · Photodiagnosis and Photodynamic Therapy
38. Sodium fluorescein and 5-aminolevulinic acid fluorescence- guided biopsy in brain lesions: a systematic review and meta-analysis
    Fernando Cotrim Gomes, Márcio Yuri Ferreira, Anna Laura Lima Larcipretti, Bruna Carolina Barbosa Freitas, Filipi Fim Andreão, Justin Turpin, Raphael Bertani, Souvik Singha, Allan Dias Polverini, Christian Candido Ferreira et al. · 2024 · Journal of Neuro-Oncology
39. Machine and Deep Learning in Hyperspectral Fluorescence-Guided Brain Tumor Surgery
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40. Towards Optical Biopsy in Glioma Surgery
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41. Next-generation laser-based photodynamic endoscopic diagnosis using 5-aminolevulinic acid for early gastric adenocarcinoma and gastric adenoma
    Takuki Sakaguchi · 2020 · Annals of Gastroenterology
42. Photodynamic therapy in glioblastoma: Detection of intraoperative inadvertent 5-ALA mediated photodynamic therapeutical effect after gross total resection
    Abel Ferrés, Alberto Di Somma, Alejandra Mosteiro, Thomaz Eduardo Topczewski, Pedro Roldán, Leire Pedrosa, Diouldé Diao, Estela Pineda, Àngels Sierra, Joaquim Enseñat et al. · 2022 · Frontiers in Oncology
43. Clinical application of the mirror irradiation technique in photodynamic therapy for malignant glioma
    Shinjiro Fukami, Jiro Akimoto, Kenta Nagai, Megumi Ichikawa, Emiyu Ogawa, Tsunenori Arai, Michihiro Kohno · 2020 · Photodiagnosis and Photodynamic Therapy
44. Protein 4.1R affects photodynamic therapy for B16 melanoma by regulating the transport of 5-aminolevulinic acid
    Bowen Li, Xiaolin Zhang, Yu Lu, Luyang Zhao, Yaxin Guo, Shuangshuang Guo, Qiaozhen Kang, Jingjing Liu, Liping Dai, Liguo Zhang et al. · 2020 · Experimental Cell Research
45. In Vitro Sonodynamic Therapy Using a High Throughput 3D Glioblastoma Spheroid Model with 5‐ALA and TMZ Sonosensitizers
    Priyankan Datta, Nan Sook Lee, Sreejesh Moolayadukkam, Rakesh P. Sahu, Xi Yu, Tianze Guo, Qifa Zhou, Y Wang, Ishwar K. Puri · 2024 · Advanced Healthcare Materials
46. Agents for Fluorescence-Guided Glioblastoma Surgery
    Eleni Romeo, Andreas G. Tzakos, Timothy Crook, Nelofer Syed, Spyridon Voulgaris, George Α. Alexiou · 2025 · Pharmaceutics
47. Effects of preoperative 5-aminolevulinic acid administration on postoperative liver enzymes after brain tumor surgery in patients with elevated preoperative liver enzymes
    Hyongmin Oh, Jung‐Bin Park, Hyun‐Kyu Yoon, Hyung‐Chul Lee, Chul‐Kee Park, Hee‐Pyoung Park · 2019 · Journal of Clinical Neuroscience
48. Ciprofloxacin enhances phototoxicity of 5-aminolevulinic acid mediated photodynamic treatment for chordoma cell lines
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49. Classification of intracranial tumors based on optical-spectral analysis
    Igor D. Romanishkin, Tatiana A. Savelieva, Anuar Ospanov, Kirill G. Linkov, S V Shugai, Sergey A. Goryajnov, Galina Valerievna Pavlova, Igor Pronin, Victor B. Loschenov · 2023 · Biomedical Photonics
50. Fluorescence lifetime imaging unravels the pathway of glioma cell death upon hypericin-induced photodynamic therapy
    Miriam C. Bassler, Jonas L. Hiller, Frank Wackenhut, Sven zur Oven‐Krockhaus, Philipp Frech, Felix F. Schmidt, Christoph Kertzscher, Tim Rammler, Rainer Ritz, Kai Braun et al. · 2024 · RSC Chemical Biology
51. Quantifying the Photochemical Damage Potential of Contrast‐Enhanced Fluorescence Imaging Products: Singlet Oxygen Production
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52. Lighthouses illuminating tumor metastasis: The application of fluorescent probes in the localization and imaging metastatic lymph nodes across various tumors
    Qi Dang, Linhao Zhang, Huipeng Ma, Xiaoshan Sun, Anguo Ren, Jiuyang Chen, Xiaohua Huang, Boyu Zhang, Wen Ce Sun · 2024 · Biomaterials
53. Protoporphyrin IX Beyond Conventional Applications: A Review of Emerging Research Directions
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54. Sources, sustainability and directions in the chemical synthesis of δ-aminolevulinic acid
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55. Relationship between the sodium fluorescein yellow fluorescence boundary and the actual boundary of high-grade gliomas during surgical resection
    Ze-Bo Chen, Xiaopeng Zhu, Wei Zheng, Yan X, Yong-Kai Huang, Hong-Jun Fang, Ai-Jun Deng, Fu-Rong Yi, Hui‐Wei Chen, Deqing Han et al. · 2021 · British Journal of Neurosurgery
56. Excision combined with photodynamic therapy for scrotal Paget’s disease in patients aged over 60 years
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57. Protoporphyrin IX Analysis from Blood and Serum in the Context of Neurosurgery of Glioblastoma
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58. Heme Biosynthesis mRNA Expression Signature: Towards a Novel Prognostic Biomarker in Patients with Diffusely Infiltrating Gliomas
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59. Possibilities of interstitial photodynamic therapy in the treatment of brain glioblastoma
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60. Immunological Insights into Photodynamic Therapy of Glioblastoma Multiforme
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61. Optical express-biopsy of gliomas using macroscopic fluorescence lifetime imaging
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62. A Tumor‐Activatable Liposomal Nanoprobe for Selective Visualization of Metastatic Lymph Nodes
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63. 5-Aminolevulinic acid (5-ALA) in paediatric brain tumour surgery—a systematic review and exploration of fluorophore alternatives
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64. Improved Protoporphyrin IX-Guided Neurosurgical Tumor Detection with Frequency-Domain Fluorescence Lifetime Imaging
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65. A Pilot Study of Fluorescence-Guided Resection of Pituitary Adenomas with Chlorin e6 Photosensitizer
    Elizaveta I. Kozlikina, Kanamat T. Efendiev, Andrey Yu. Grigoriev, Olesia Y. Bogdanova, И. С. Трифонов, Vladimir V. Krylov, Victor B. Loschenov · 2022 · Bioengineering
66. PINPOINT® can be used for photodynamic diagnosis based on 5-aminolevulinic acid-induced protoporphyrinIX in gastric cancer surgery
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67. Video-Mosaicked Handheld Dual-Axis Confocal Microscopy of Gliomas: An ex vivo Feasibility Study in Humans
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68. Lasers in Live Cell Microscopy
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69. 5-Aminolevulinic acid-mediated protoporphyrin IX accumulation in the tumor microenvironment of glioma and its implications for 5-aminolevulinic acid-based local tumor therapies: A review of the literature
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70. Does 5-ALA Fluorescence Microscopy Improve Complete Resectability in Cerebral/Cerebellar Metastatic Surgery? A Retrospective Data Analysis from a Cranial Center
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71. Cytocidal Effects of Interstitial Photodynamic Therapy Using Talaporfin Sodium and a Semiconductor Laser in a Rat Intracerebral Glioma Model
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72. Three Decades of Photodynamic Therapy for Glioblastoma: A Comprehensive Scientometric Analysis
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73. Analysis of corticosteroid and antiepileptic drug treatment effects on heme biosynthesis mRNA expression in lower-grade gliomas: Potential implications for 5-ALA metabolization
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74. Minimally invasive surgical treatment of glioblastomas using interstitial photodynamic therapy
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80. Illuminate Resection Pathways with Fluorescence Guidance in Glioma Surgery: Case Reports and Systematic Review
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82. 5-Aminolevulinic acid improves spatial recognition memory in mice
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84. Efficacy and safety of bevacizumab combined with temozolomide in the treatment of recurrent malignant gliomas and its influence on serum tumor markers.
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85. Alteration of Mesenchymal Stem Cells Isolated from Glioblastoma Multiforme under the Influence of Photodynamic Treatment
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87. Solubilization of Hexyl Aminolevulinate by Surfactants for Tumor Fluorescence Detection
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88. Influence of oxy-, deoxy- and met-hemoglobin absorption in interstitial photodynamic therapy
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89. 5-ALA localises to the autophagy compartment and increases its fluorescence upon autophagy enhancement through caloric restriction and spermidine treatment in human glioblastoma
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90. Advancement of fluorescent aminopeptidase probes for rapid cancer detection–current uses and neurosurgical applications
    Takenori Shimizu, Shota Tanaka, Yosuke Kitagawa, Yusuke Sakaguchi, Mako Kamiya, Shunsaku Takayanagi, Hirokazu Takami, Yasuteru Urano, Nobuhito Saito · 2024 · Frontiers in Surgery
91. Surgical identification of brain tumour margins through impedance monitoring and electrocorticography and the potential for their combined use: A systematic review
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92. Spinal cordectomy for the management of thoracic malignant intraspinal tumors in paraplegic or irreversibly, severely paraparetic patients: A technical remark
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93. Photodynamic Treatment Using a Small Diameter Diffused Light Irradiation Probe Made of Plastic Optical Fiber
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94. Achievements and prospects for further development of photodynamic therapy technology in the treatment of cerebral tumors
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95. Study of possibility of cell recognition in brain tumors
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96. Protoporphyrin IX purification from blood and serum for mass analysis – Considerations with respect to neurosurgery
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97. Label-free fluorescence lifetime imaging for real-time guidance of stereotactic biopsy: A feasibility study in brain cancer patients
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