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Mass spectrometry in bioinorganic analytical chemistry

Open access
Łobiński, Ryszard, Schaumlöffel, Dirk, Szpunar, Joanna·2006·Mass Spectrometry Reviews

Abstract

A considerable momentum has recently been gained by in vitro and in vivo studies of interactions of trace elements in biomolecules due to advances in inductively coupled plasma mass spectrometry (ICP MS) used as a detector in chromatography and capillary and planar electrophoresis. The multi‐isotopic (including non‐metals such as S, P, or Se) detection capability, high sensitivity, tolerance to matrix, and large linearity range regardless of the chemical environment of an analyte make ICP MS a valuable complementary technique to electrospray MS and MALDI MS. This review covers different facets of the recent progress in metal speciation in biochemistry, including probing in vitro interactions between metals and biomolecules, detection, determination, and structural characterization of heteroatom‐containing molecules in biological tissues, and protein monitoring and quantification via a heteroelement (S, Se, or P) signal. The application areas include environmental chemistry, plant and animal biochemistry, nutrition, and medicine. © 2005 Wiley Periodicals, Inc. Mass Spec Rev 25:255–289, 2006

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Metadata

Authors
Łobiński, R., Schaumlöffel, D., & Szpunar, J.
Venue
Mass Spectrometry Reviews
Publisher
Wiley
Published
2005-11-04
Volume
25
Issue
2
Pages
255-289
ISSN
  • 0277-7037 (ISSN-L)
  • 1098-2787
OpenAlex
W1974235044
Cited by
212
References
6
FWCI
8.24
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Mass spectrometry in bioinorganic analytical chemistry. https://app.cochat.ai/papers/10.1002/mas.20069
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Łobiński, R., Schaumlöffel, D., & Szpunar, J. (2006). Mass spectrometry in bioinorganic analytical chemistry. Mass Spectrometry Reviews. https://doi.org/10.1002/mas.20069

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