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Cited by 237

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Mitochondrial complex I and IV activities in leukocytes from patients with parkin mutations

Müftüoglu, Meltem, Elibol, Bülent, Dalmızrak, Özlem, Ercan, Ayse, Kulaksız, Gülnihal, Ögüs, Hamdi, Dalkara, Turgay, Özer, Nazmi·2004·Movement Disorders

Abstract

The parkin protein functions as a RING‐type ubiquitin protein ligase. Considering the possibility that impaired ubiquitin‐proteosomal system activity may impair antioxidant defenses and enhance oxidative stress, we have investigated the activity of mitochondrial respiratory enzymes in patients with parkin gene mutations. A significant decrease in the leukocyte complex I activity was found both in patients with parkin mutations (62.5%) and idiopathic PD (64.5%) compared with age‐matched controls (P < 0.001). Complex IV activity was also decreased significantly in idiopathic PD patients (60%), but no difference was detected between controls and patients with parkin mutations. © 2003 Movement Disorder Society

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Crossref · 10.1002/mds.10695

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Metadata

Authors
Müftüoglu, M., Elibol, B., Dalmızrak, Ö., Ercan, A., Kulaksız, G., Ögüs, H., Dalkara, T., & Özer, N.
Venue
Movement Disorders
Publisher
Wiley
Published
2003-12-15
Volume
19
Issue
5
Pages
544-548
ISSN
  • 0885-3185 (ISSN-L)
  • 1531-8257
OpenAlex
W2166263915
Cited by
237
References
4
FWCI
3.52
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Mitochondrial complex I and IV activities in leukocytes from patients with parkin mutations. https://app.cochat.ai/papers/10.1002/mds.10695
The paper
Müftüoglu, M., Elibol, B., Dalmızrak, Ö., Ercan, A., Kulaksız, G., Ögüs, H., Dalkara, T., & Özer, N. (2004). Mitochondrial complex I and IV activities in leukocytes from patients with parkin mutations. Movement Disorders. https://doi.org/10.1002/mds.10695

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