The DOI matches its Crossref record.
Dopamine transporters, D2 receptors, and glucose metabolism in corticobasal degeneration
Abstract
Alterations in presynaptic and postsynaptic dopaminergic system and cerebral glucose metabolism in corticobasal degeneration (CBD) were assessed to evaluate the potential usefulness of different imaging methods for CBD. 123 I‐FP‐CIT/123 I‐β‐CIT SPECT and 123 I‐IBZM SPECT as well as 18 F‐FDG PET were performed in eight CBD patients. Decreased presynaptic dopamine transporter binding was found in all CBD patients while D2 receptor binding was reduced in only one patient. 18 F‐FDG PET displayed a contralateral hypometabolism in cortical and subcortical areas in seven out of eight patients. Our results demonstrate that glucose metabolism and DAT are reduced, while D2 receptors may be frequently preserved in CBD. © 2006 Movement Disorder Society
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Dopaminergic imaging can be abnormal in other neurodegenerative disorders where dopaminergic transmission is affected, such as FTD, CBD, PSP, and MSA.
“Dopaminergic imaging can be abnormal in other neurodegenerative disorders where dopaminergic transmission is affected, such as FTD, CBD, PSP and MSA [148–150].”
From The use of neuroimaging techniques in the early and differential diagnosis of dementia (2023) · cites this paper as [148]
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 15
- 10.1001/archneur.1993.00540050063017 · DOI
- Plotkin M, 2005, Combined 123I‐FP‐CIT and 123I‐IBZM SPECT for the diagnosis of parkinsonian syndromes: study on 72 patients, J Neural Transm, 211, 667
- Schwarz J, 1993, 123I‐iodobenzamide‐SPECT in 83 patients with de novo parkinsonism, Neurology, 43, 17
- 10.1016/S1474-4422(04)00936-6 · DOI
- 10.1212/01.WNL.0000149403.14458.7F · DOI
- Plotkin M, 2003, Use of statistical parametric mapping of 18F‐FDG‐PET in frontal lobe epilepsy, Nuklearmedizin, 42, 190, 10.1055/s-0038-1625189 · DOI
- 10.1046/j.1440-1789.2001.00403.x · DOI
- 10.1159/000117090 · DOI
- 10.1002/mds.870130107 · DOI
- 10.1093/brain/112.5.1171 · DOI
- 10.1007/s00401-003-0711-4 · DOI
- 10.1136/jnnp.54.10.856 · DOI
- 10.1016/S0022-510X(02)00102-8 · DOI
- 10.1016/j.neulet.2005.03.057 · DOI
- Shiozawa M, 2000, Corticobasal degeneration: an autopsy case clinically diagnosed as progressive supranuclear palsy, Clin Neuropathol, 54, 1029
Cited by
Sorted by citations
The use of neuroimaging techniques in the early and differential diagnosis of dementia
Chouliaras, L., & O’Brien, J. T. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02215-8 · Cited by 221
“Dopaminergic imaging can be abnormal in other neurodegenerative disorders where dopaminergic transmission is affected, such as FTD, CBD, PSP and MSA [148 – 150].”
Background
Metadata
- Authors
- Klaffke, S., Kuhn, A. A., Plotkin, M., Amthauer, H., Harnack, D., Felix, R., & Kupsch, A.
- Affiliations
- Charité – Universitätsmedizin Berlin (DE)
- Corresponding author
- Kupsch, Andreas
- Venue
- Movement Disorders
- Publisher
- Wiley
- Published
- 2006-06-13
- Volume
- 21
- Issue
- 10
- Pages
- 1724-1727
- ISSN
- 0885-3185 (ISSN-L)
- 1531-8257
- OpenAlex
- W2030027599
- Cited by
- 87
- References
- 0
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 5 · 2022: 4 · 2021: 6 · 2020: 5 · 2019: 3 · 2018: 5 · 2017: 4 · 2016: 7 · 2015: 4 · 2014: 11 · 2013: 5 · 2012: 6
- FWCI
- 1.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Movement Disorders (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Berlin Neuroscience Imaging Center (BMBF 01GO0201)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Keywords
- corticobasal degeneration, dopamine transporter, dopamine D2 receptor, brain glucose metabolism, 123I-FP-CIT, [123I]beta-CIT, [123I]IBZM, 18F-FDG PET, SPECT imaging
- MeSH terms
- Aged, Benzamides, Blood Glucose, Brain, Cerebral Cortex, Cocaine, Corpus Striatum, Dominance, Cerebral, Female, Humans, Male, Middle Aged, Parietal Lobe, Pyrrolidines, Tropanes, Tomography, Emission-Computed, Single-Photon, Receptors, Dopamine D2, Fluorodeoxyglucose F18, Parkinsonian Disorders, Positron-Emission Tomography
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
