The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Long‐term results of a multicenter study on subthalamic and pallidal stimulation in Parkinson's disease
Open accessAbstract
We report the 5 to 6 year follow‐up of a multicenter study of bilateral subthalamic nucleus (STN) and globus pallidus internus (GPi) deep brain stimulation (DBS) in advanced Parkinson's disease (PD) patients. Thirty‐five STN patients and 16 GPi patients were assessed at 5 to 6 years after DBS surgery. Primary outcome measure was the stimulation effect on the motor Unified Parkinson's Disease Rating Scale (UPDRS) assessed with a prospective cross‐over double‐blind assessment without medications (stimulation was randomly switched on or off). Secondary outcomes were motor UPDRS changes with unblinded assessments in off‐ and on‐medication states with and without stimulation, activities of daily living (ADL), anti‐PD medications, and dyskinesias. In double‐blind assessment, both STN and GPi DBS were significantly effective in improving the motor UPDRS scores (STN, P < 0.0001, 45.4%; GPi, P = 0.008, 20.0%) compared with off‐stimulation, regardless of the sequence of stimulation. In open assessment, both STN‐ and GPi‐DBS significantly improved the off‐medication motor UPDRS when compared with before surgery (STN, P < 0.001, 50.5%; GPi, P = 0.002, 35.6%). Dyskinesias and ADL were significantly improved in both groups. Anti‐PD medications were significantly reduced only in the STN group. Adverse events were more frequent in the STN group. These results confirm the long‐term efficacy of STN and GPi DBS in advanced PD. Although the surgical targets were not randomized, there was a trend to a better outcome of motor signs in the STN‐DBS patients and fewer adverse events in the GPi‐DBS group. © 2010 Movement Disorder Society
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Cites
Unified Parkinson's Disease Rating Scale
(2012) · SpringerReference · doi:10.1007/springerreference_184495 · Cited by 3,066
A Randomized Trial of Deep-Brain Stimulation for Parkinson's Disease
Deuschl, G., Schade-Brittinger, C., Krack, P., Volkmann, J., Schäfer, H., Bötzel, K., Daniels, C., Deutschländer, A., Dillmann, U., Eisner, W., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa060281 · Cited by 2,944
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Self-citation(2001) · New England Journal of Medicine · doi:10.1056/nejmoa000827 · Cited by 1,514
Bilateral deep brain stimulation in Parkinson's disease: a multicentre study with 4 years follow-up
Rodriguez-Oroz, M. C., Obeso, J. A., Lang, A. E., Houeto, J.-L., Pollak, P., Rehncrona, S., Kulisevsky, J., Albanese, A., Volkmann, J., Hariz, M. I., et al. (2005) · Brain · doi:10.1093/brain/awh571 · Cited by 1,057
Self-citationDeep brain stimulation for Parkinson’s disease
Benabid, A. L. (2003) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2003.11.001 · Cited by 1,046
Self-citationCore assessment program for intracerebral transplantations (CAPIT)
Langston, J. W., Widner, H., Goetz, C. G., Brooks, D., Fahn, S., Freeman, T., & Watts, R. (1992) · Movement Disorders · doi:10.1002/mds.870070103 · Cited by 1,008
Subthalamic nucleus deep brain stimulation: Summary and meta-analysis of outcomes
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Self-citationCore assessment program for surgical interventional therapies in Parkinson's disease (CAPSIT-PD)
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Self-citationClosed-Loop Deep Brain Stimulation Is Superior in Ameliorating Parkinsonism
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Metadata
- Authors
- Moro, E., Lozano, A. M., Pollak, P., Agid, Y., Rehncrona, S., Volkmann, J., Kulisevsky, J., Obeso, J. A., Albanese, A., Hariz, M. I., Quinn, N. P., Speelman, J. D., Benabid, A. L., Fraix, V., Mendes, A., Welter, M., Houeto, J., Cornu, P., Dormont, D., Tornqvist, A. L., Ekberg, R., Schnitzler, A., Timmermann, L., Wojtecki, L., Gironell, A., Rodriguez‐Oroz, M. C., Guridi, J., Bentivoglio, A. R., Contarino, M. F., Romito, L., Scerrati, M., Janssens, M., & Lang, A. E.
- Venue
- Movement Disorders
- Publisher
- Wiley
- Published
- 2010-04-15
- Volume
- 25
- Issue
- 5
- Pages
- 578-586
- ISSN
- 0885-3185 (ISSN-L)
- 1531-8257
- OpenAlex
- W2169661540
- Cited by
- 468
- References
- 26
- FWCI
- 25.01
- Type
- journal article
- Language
- en
- Open access
- green
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- Moro, E., Lozano, A. M., Pollak, P., Agid, Y., Rehncrona, S., Volkmann, J., Kulisevsky, J., Obeso, J. A., Albanese, A., Hariz, M. I., Quinn, N. P., Speelman, J. D., Benabid, A. L., Fraix, V., Mendes, A., Welter, M., Houeto, J., Cornu, P., Dormont, D., . . . Lang, A. E. (2010). Long‐term results of a multicenter study on subthalamic and pallidal stimulation in Parkinson's disease. Movement Disorders. https://doi.org/10.1002/mds.22735
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