The DOI matches its Crossref record; 175 of the 175 references it cites were found in a registry or an index.
Biologically active quinoline and quinazoline alkaloids part I
Open accessAbstract
Quinoline and quinazoline alkaloids, two important classes of N‐based heterocyclic compounds, have attracted tremendous attention from researchers worldwide since the 19th century. Over the past 200 years, many compounds from these two classes were isolated from natural sources, and most of them and their modified analogs possess significant bioactivities. Quinine and camptothecin are two of the most famous and important quinoline alkaloids, and their discoveries opened new areas in antimalarial and anticancer drug development, respectively. In this review, we survey the literature on bioactive alkaloids from these two classes and highlight research achievements prior to the year 2008 (Part I). Over 200 molecules with a broad range of bioactivities, including antitumor, antimalarial, antibacterial and antifungal, antiparasitic and insecticidal, antiviral, antiplatelet, anti‐inflammatory, herbicidal, antioxidant and other activities, were reviewed. This survey should provide new clues or possibilities for the discovery of new and better drugs from the original naturally occurring quinoline and quinazoline alkaloids.
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Metadata
- Authors
- Shang, X., Morris‐Natschke, S. L., Liu, Y., Guo, X., Xu, X., Goto, M., Li, J., Yang, G., & Lee, K.
- Venue
- Medicinal Research Reviews
- Publisher
- Wiley
- Published
- 2017-09-13
- Volume
- 38
- Issue
- 3
- Pages
- 775-828
- ISSN
- 0198-6325 (ISSN-L)
- 1098-1128
- OpenAlex
- W2756098300
- Cited by
- 437
- References
- 175
- FWCI
- 9.40
- Type
- journal article
- Language
- en
- Open access
- green
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- Shang, X., Morris‐Natschke, S. L., Liu, Y., Guo, X., Xu, X., Goto, M., Li, J., Yang, G., & Lee, K. (2018). Biologically active quinoline and quinazoline alkaloids part I. Medicinal Research Reviews. https://doi.org/10.1002/med.21466
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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