Emerging roles of allosteric modulators in the regulation of protein‐protein interactions (PPIs): A new paradigm for PPI drug discovery

Cites (227)

Items 201–227 of 227

1. The chemical diversity and structure-based discovery of allosteric modulators for the PIF-pocket of protein kinase PDK1
   Xinyuan Xu, Yingyi Chen, Qiang Fu, Duan Ni, Jian Zhang, Xiaolong Li, Shaoyong Lu · 2019 · Journal of Enzyme Inhibition and Medicinal Chemistry
2. Clinical Development of Anti-mitotic Drugs in Cancer
   Anna-Maria Olziersky, Sana Intidhar Labidi‐Galy · 2017 · Advances in experimental medicine and biology
3. EcID. A database for the inference of functional interactions in E. coli
   Eduardo Andrés‐León, Iakes Ezkurdia, Beatriz García-Jiménez, Alfonso Valencia, David Juan · 2008 · Nucleic Acids Research
4. Use of BRET to Study Protein–Protein Interactions In Vitro and In Vivo
   Shalini Dimri, Soumya Basu, Abhijit De · 2016 · Methods in molecular biology
5. Small Molecule Targeting of Protein–Protein Interactions through Allosteric Modulation of Dynamics
   Benjamin P. Cossins, Alastair D. G. Lawson · 2015 · Molecules
6. Detection of Protein–Protein Interactions and Posttranslational Modifications Using the Proximity Ligation Assay: Application to the Study of the SUMO Pathway
   Marko Ristic, Frédérique Brockly, Marc Piechaczyk, Guillaume Bossis · 2016 · Methods in molecular biology
7. Toward an understanding of the sequence and structural basis of allosteric proteins
   Xiao‐Bai Li, Yingyi Chen, Shaoyong Lu, Zhimin Huang, Xinyi Liu, Qi Wang, Ting Shi, Jian Zhang · 2013 · Journal of Molecular Graphics and Modelling
8. Are there physicochemical differences between allosteric and competitive ligands?
   Smith, Richard D., Lu, Jing, Carlson, Heather A. · 2017 · PLOS Computational Biology
9. Computational Insights into the Interactions between Calmodulin and the c/nSH2 Domains of p85α Regulatory Subunit of PI3Kα: Implication for PI3Kα Activation by Calmodulin
   Duan Ni, Dingyu Liu, Jian Zhang, Shaoyong Lu · 2018 · International Journal of Molecular Sciences
10. Temsirolimus
    Michael Schulze, Christian Stock, Massimo Zaccagnini, Doğu Teber, Jens Jochen Rassweiler · 2014 · Recent results in cancer research/Recent Results in Cancer Research
11. Mapping Protein–Protein Interactions Using Affinity Purification and Mass Spectrometry
    Chin‐Mei Lee, Christopher Adamchek, Ann Feke, Dmitri A. Nusinow, Joshua M. Gendron · 2017 · Methods in molecular biology
12. Are the Apo Proteins Suitable for the Rational Discovery of Allosteric Drugs?
    Xiaoli An, Shaoyong Lu, Kun Song, Qiancheng Shen, Meilan Huang, Xiaojun Yao, Huanxiang Liu, Jian Zhang · 2018 · Journal of Chemical Information and Modeling
13. Docetaxel for the treatment of bladder cancer
    Costantine Albany, Guru Sonpavde · 2015 · Expert Opinion on Investigational Drugs
14. Twenty years of protein interaction studies for biological function deciphering
    Pierre Legrain, Jean‐Christophe Rain · 2014 · Journal of Proteomics
15. Protein-Protein Interaction Detection Via Mass Spectrometry-Based Proteomics
    Benedetta Turriziani, Alex von Kriegsheim, Stephen R. Pennington · 2016 · Advances in experimental medicine and biology
16. Using the Yeast Two-Hybrid System to Identify Protein–Protein Interactions
    Edgar Antonio Rodríguez‐Negrete, Eduardo R. Bejarano, Araceli G. Castillo · 2013 · Methods in molecular biology
17. MoNetFamily: a web server to infer homologous modules and module–module interaction networks in vertebrates
    Chun‐Yu Lin, Yi-Wei Lin, Shang-Wen Yu, Yu‐Shu Lo, Jinn‐Moon Yang · 2012 · Nucleic Acids Research
18. The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex
    Nicola Salvi, Evangelos Papadopoulos, Martin J Blackledge, Gerhard Wagner · 2016 · Angewandte Chemie International Edition
19. Can emerging drug classes improve R&D productivity?
    Christoph Meier, Sarah Cairns‐Smith, Ulrik Schulze · 2013 · Drug Discovery Today
20. Novel Histone H3 Binding Protein ORF158L from the Singapore Grouper Iridovirus
    Bích Ngọc Trần, Liming Chen, Yang Liu, Jinlu Wu, Adrián Velázquez‐Campoy, Jayaraman Sivaraman, Choy L. Hew · 2011 · Journal of Virology
21. PRISM-EM: template interface-based modelling of multi-protein complexes guided by cryo-electron microscopy density maps
    Guray Kuzu, Özlem Keskin, Ruth Nussinov, Attila Gürsoy · 2016 · Acta Crystallographica Section D Structural Biology
22. The Hans Neurath Award lecture of The Protein Society: Proteins—A testament to physics, chemistry, and evolution
    Janet M. Thornton · 2001 · Protein Science
23. Path2PPI: an R package to predict protein–protein interaction networks for a set of proteins
    Oliver Philipp, Heinz Dieter Osiewacz, Ina Koch · 2016 · Bioinformatics
24. Detection of Protein-Protein Interaction Using Bimolecular Fluorescence Complementation Assay
    Cau D. Pham · 2015 · Methods in molecular biology
25. Measuring NLR Oligomerization V: In Situ Proximity Ligation Assay
    Yung‐Hsuan Wu, Ming‐Zong Lai · 2016 · Methods in molecular biology
26. The autophagy interaction network of the aging model Podospora anserina
    Oliver Philipp, Andréa Hamann, Heinz Dieter Osiewacz, Ina Koch · 2017 · BMC Bioinformatics
27. The computational prediction of protein assemblies
    Anna Luna Tramontano · 2017 · Current Opinion in Structural Biology