The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A dark brown roast coffee blend is less effective at stimulating gastric acid secretion in healthy volunteers compared to a medium roast market blend
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“This effect depends on the degree of roasting, with dark roasted coffee being less effective in stimulating gastric acid release, possibly because of the presence of a higher amount of N-methylpyridinium and smaller amounts of chlorogenic acids, trigonelline, and βN-alkanoyl-5-hydroxytryptamides (C5HTs).”
From Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update (2022) · cites this paper as [17]
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Citations
Cites
Coffee and Gastrointestinal Function: Facts and Fiction: A Review
J. Boekema, M. S. (1999) · Scandinavian Journal of Gastroenterology · doi:10.1080/003655299750025525 · Cited by 164
Rubach, M., Lang, R., Skupin, C., Hofmann, T., & Somoza, V. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf904493f · Cited by 31
Research works printed but not linked: 19
- Zheng, 2007, Lifestyle factors and risk for symptomatic gastro-esophageal reflux in monozygotic twins, Gastroenterology, 132, 87, 10.1053/j.gastro.2006.11.019 · DOI · Paper page
- Fehlau, 1990, [Effect of untreated and non-irritating purified coffee and carbonic acid hydroxytryptamides on the gastric mucosa in the rat], Z. Gastroenterol., 28, 234
- Pehl, 1997, The effect of decaffeination of coffee on gastro-oesophageal reflux in patients with reflux disease, Aliment. Pharmacol. Ther., 11, 483, 10.1046/j.1365-2036.1997.00161.x · DOI · Paper page
- Wendl, 1994, Effect of decaffeination of coffee or tea on gastro-oesophageal reflux, Aliment. Pharmacol. Ther., 8, 283, 10.1111/j.1365-2036.1994.tb00289.x · DOI · Paper page
- Ehrlich, 1999, Effect of processed and non-processed coffee samples on gastric potential difference-study with healthy male Helicobacter pylori-positive and Helicobacter pylori-negative volunteers, Arzneimittel-Forsch, 49, 626
- Darboven, 1997, Europäisches Patentblatt 1997/05, European Patent Office
- Lang, 2010, Quantitation of N-beta-alkanoyl-5-hydroxytryptamides in coffee by means of LC-MS/MS-SIDA and assessment of their gastric acid secretion potential using the HGT-1 cell assay, J. Agric. Food. Chem., 58, 1593, 10.1021/jf903612h · DOI
- Rubach, 2012, Multi-parametric approach to identify coffee components that regulate mechanisms of gastric acid secretion, Mol. Nutr. Food Res., 56, 325, 10.1002/mnfr.201100453 · DOI · Paper page
- Stadler, 2002, Alkylpyridiniums. 1. Formation in model systems via thermal degradation of trigonelline, J. Agric. Food Chem., 50, 1192, 10.1021/jf011234k · DOI
- Stadler, 2002, Alkylpyridiniums. 2. Isolation and quantification in roasted and ground coffees, J. Agric. Food Chem., 50, 1200, 10.1021/jf011235c · DOI
- Somoza, 2003, Activity-guided identification of a chemopreventive compound in coffee beverage using in vitro and in vivo techniques, J. Agric. Food Chem., 51, 6861, 10.1021/jf034750e · DOI
- Boettler, 2011, Coffees rich in chlorogenic acid or N-methylpyridinium induce chemopreventive phase II-enzymes via the Nrf2/ARE pathway in vitro and in vivo, Mol. Nutr. Food Res., 55, 798, 10.1002/mnfr.201100115 · DOI
- Boettler, 2011, Coffee constituents as modulators of Nrf2 nuclear translocation and ARE (EpRE)-dependent gene expression, J. Nutr. Biochem., 22, 426, 10.1016/j.jnutbio.2010.03.011 · DOI
- Rubach, 2008, Time-dependent component-specific regulation of gastric acid secretion-related proteins by roasted coffee constituents, Ann. N. Y. Acad. Sci., 1126, 310, 10.1196/annals.1433.061 · DOI · Paper page
- Weiss, 2010, Measurement of the intracellular pH in human stomach cells: a novel approach to evaluate the gastric acid secretory potential of coffee beverages, J. Agric. Food. Chem., 58, 1976, 10.1021/jf903614d · DOI
- Liszt, 2012, Identification of organic acids in wine that stimulate mechanisms of gastric acid secretion, J. Agric. Food. Chem., 60, 7022, 10.1021/jf301941u · DOI
- Rubach, 2010, Activity-guided fractionation to characterize a coffee beverage that effectively down-regulates mechanisms of gastric acid secretion as compared to regular coffee, J. Agric. Food. Chem., 58, 4153, 10.1021/jf904493f · DOI · Paper page
- Brzozowski, 2008, Therapeutic potential of 1-methylnicotinamide against acute gastric lesions induced by stress: role of endogenous prostacyclin and sensory nerves, J. Pharmacol. Exp. Ther., 326, 105, 10.1124/jpet.108.136457 · DOI
- Nebesny, 2002, Effect of the roasting method on the content of 5-hydroxytryptamides of carboxylic acids in roasted coffee beans, Die Nahrung, 46, 279, 10.1002/1521-3803(20020701)46:4<279::AID-FOOD279>3.0.CO;2-R · DOI
Cited by
Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update
Nehlig, A. (2022) · Nutrients · doi:10.3390/nu14020399 · Cited by 158
Metadata
- Authors
- Rubach, M., Lang, R., Bytof, G., Stiebitz, H., Lantz, I., Hofmann, T., & Somoza, V.
- Affiliations
- German Research Center for Food Chemistry; Freising Germany
- Chair of Food Chemistry and Molecular and Sensory Science; Technische Universität München; Freising Germany
- Tchibo GmbH; Hamburg Germany
- Venue
- Molecular Nutrition & Food Research
- Publisher
- Wiley
- Published
- 2014-02-08
- Volume
- 58
- Issue
- 6
- Pages
- 1370-1373
- ISSN
- 1613-4125
- Cited by
- 28
- References
- 2
- Language
- en
- Licence
- doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 570 d)
- Funders
- FEI (Forschungskreis der Ernährungsindustrie e.V., Bonn, Germany) the AiF (Arbeitsgemeinschaft industrieller Forschung)
- German Ministry of Economics (14042 N)
- German Academic Exchange Service (DAAD)
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- CoChat. (2026). Citation check: A dark brown roast coffee blend is less effective at stimulating gastric acid secretion in healthy volunteers compared to a medium roast market blend. https://app.cochat.ai/papers/10.1002/mnfr.201300890
- The paper
- Rubach, M., Lang, R., Bytof, G., Stiebitz, H., Lantz, I., Hofmann, T., & Somoza, V. (2014). A dark brown roast coffee blend is less effective at stimulating gastric acid secretion in healthy volunteers compared to a medium roast market blend. Molecular Nutrition & Food Research. https://doi.org/10.1002/mnfr.201300890
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.