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Systematic review of chorioamnionitis and cerebral palsy
Abstract
In a recent meta‐analysis evaluating the relationship between chorioamnionitis and cerebral palsy, we found that chorioamnionitis is a risk factor for both cerebral palsy and cystic periventricular leukomalacia (cPVL). The current paper extends the meta‐analysis by including studies published in the year 2000, and by further evaluating the causes of heterogeneity among individual study results. Using a random effects model, clinical chorioamnionitis was significantly associated with both cerebral palsy (RR 1.9, 95% CI 1.5–2.5) and cPVL (RR 2.6, 95% CI 1.7–3.9). Sources of heterogeneity included widely varying practices in the diagnosis of clinical chorioamnionitis, different gestational age characteristics, and varying study year. We conclude that based on the available literature, chorioamnionitis is a risk factor for both cerebral palsy and cPVL. MRDD Research Reviews 2002;8:25–29. © 2002 Wiley‐Liss, Inc.
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Cites
Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease
(1959) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/22.4.719 · Cited by 14,689
Cited by
Meyer, U., Nyffeler, M., Engler, A., Urwyler, A., Schedlowski, M., Knuesel, I., Yee, B. K., & Feldon, J. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.0099-06.2006 · Cited by 774
Boksa, P. (2010) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2010.03.005 · Cited by 603
Inder, T. E., Wells, S. J., Mogridge, N. B., Spencer, C., & Volpe, J. J. (2003) · The Journal of Pediatrics · doi:10.1067/s0022-3476(03)00357-3 · Cited by 521
The Consequences of Chorioamnionitis: Preterm Birth and Effects on Development
Galinsky, R., Polglase, G. R., Hooper, S. B., Black, M. J., & Moss, T. J. M. (2013) · Journal of Pregnancy · doi:10.1155/2013/412831 · Cited by 280
The complex aetiology of cerebral palsy
Korzeniewski, S. J., Slaughter, J., Lenski, M., Haak, P., & Paneth, N. (2018) · Nature Reviews Neurology · doi:10.1038/s41582-018-0043-6 · Cited by 264
Metadata
- Authors
- Wu, Y. W.
- Venue
- Mental Retardation and Developmental Disabilities Research Reviews
- Publisher
- Wiley
- Published
- 2002-01
- Volume
- 8
- Issue
- 1
- Pages
- 25-29
- ISSN
- 1080-4013 (ISSN-L)
- 1098-2779
- OpenAlex
- W2021558565
- Cited by
- 230
- References
- 1
- FWCI
- 2.71
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.