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Measurement of translational displacement probabilities by NMR: An indicator of compartmentation
Abstract
We introduce and demonstrate an NMR pulsed gradient stimulated echo method of directly obtaining the molecular translational displacement probability (displacement profile) of a liquid. The temporal development of the displacement profile reflects the presence of diffusion, restrictions to diffusion (e.g., walls, membranes), flow, and spatially dependent relaxation sinks. This approach allows the study of compartments which are too small to be observed by conventional NMR imaging methods. The distribution of spatial properties of compartments can be characterized over a spatial field of about 0.1 to 25 μm, completely independent of the absolute spatial location of the individual compartments. © 1990 Academic Press, Inc.
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Cited by
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Basser, P. J., Mattiello, J., & LeBihan, D. (1994) · Biophysical Journal · doi:10.1016/s0006-3495(94)80775-1 · Cited by 5,970
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Beaulieu, C. (2002) · NMR in Biomedicine · doi:10.1002/nbm.782 · Cited by 4,628
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Jones, D. K., Knösche, T. R., & Turner, R. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2012.06.081 · Cited by 2,402
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Assaf, Y., & Pasternak, O. (2008) · Journal of Molecular Neuroscience · doi:10.1007/s12031-007-0029-0 · Cited by 1,537
Metadata
- Authors
- Cory, D. G.
- Venue
- Magnetic Resonance in Medicine
- Publisher
- Wiley
- Published
- 1990-06
- Volume
- 14
- Issue
- 3
- Pages
- 435-444
- ISSN
- 0740-3194 (ISSN-L)
- 1522-2594
- OpenAlex
- W2056232814
- Cited by
- 429
- References
- 0
- FWCI
- 4.76
- Type
- journal article
- Language
- en
- Open access
- closed
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