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Quantitative 1H magnetization transfer imaging in vivo
Abstract
A major factor contributing to proton (1 H) spin‐lattice relaxation in biological tissues is believed to be magnetization transfer between 'H in free bulk water and 1 H in restricted motion associated with macromolecules. We have shown recently that saturation transfer is an effective approach for studying this magnetization transfer process. Herein the determination of magnetization transfer rates in biological tissues is further analyzed by considering the time and power dependencies of saturation transfer. Following these analyses, quantitative magnetization transfer rate constant image maps were collected from the kidney in vivo. These rate constant images may prove useful in quantitative tissue characterization and in the determination of tissue‐specific 1 H relaxation mechanisms. © 1991 Academic Press, Inc.
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Cited by
Quantitative interpretation of magnetization transfer
Henkelman, R. M., Huang, X., Xiang, Q., Stanisz, G. J., Swanson, S. D., & Bronskill, M. J. (1993) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910290607 · Cited by 734
Mole, J. P., Fasano, F., Evans, J., Sims, R., Hamilton, D. A., Kidd, E., & Metzler-Baddeley, C. (2020) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2020.06.014 · Cited by 20
APOE-ε4-related differences in left thalamic microstructure in cognitively healthy adults
Mole, J. P., Fasano, F., Evans, J., Sims, R., Kidd, E., Aggleton, J. P., & Metzler-Baddeley, C. (2020) · Scientific Reports · doi:10.1038/s41598-020-75992-9 · Cited by 15
Magnetic Resonance Imaging of the Common Marmoset Head
Lee, V.-M., Burdett, N. G., Carpenter, T. A., Herrod, N. J., James, M. F., & Hall, L. D. (1998) · Alternatives to Laboratory Animals · doi:10.1177/026119299802600309 · Cited by 5
Metadata
- Authors
- Eng, J., Ceckler, T. L., & Balaban, R. S.
- Venue
- Magnetic Resonance in Medicine
- Publisher
- Wiley
- Published
- 1991-02
- Volume
- 17
- Issue
- 2
- Pages
- 304-314
- ISSN
- 0740-3194 (ISSN-L)
- 1522-2594
- OpenAlex
- W1753277309
- Cited by
- 236
- References
- 0
- FWCI
- 20.81
- Type
- journal article
- Language
- en
- Open access
- closed
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